Public sequence databases contain an ever growing collection of yet unexplored enzyme sequences that can be of great avail for biocatalysis. Using different database mining approaches, we have significantly increased the number of available halohydrin dehalogenases for the selective synthesis of ?-substituted alcohols, and ?-etherases for the selective cleavage of ?-O-4 aryl ether bonds in lignin. An overview on the in silico identification and biochemical characterization of those enzymes will be presented as well as examples for their biocatalytic application and protein engineering.
Institut für Molekulare Biotechnologie, Forum Technik & Gesellschaft, TU Graz, alumniTUGraz 1887
2. March 2018, 10:00 AM - 13:30
TU Graz, Neue Technik, Room E 3.1, Petersgasse 12, GF and Discussion Room BKEG053, Petersgasse 14, GF, 8010 Graz, Austria
Language: English
Patricia GÖTZ
alumniTUGraz 1887
teilnahme@TUGraz.at
Phone: +43 316 873 7191