IBC - Publications

2024

Bianca Kerschbaumer, Massimo G. Totaro, Michael Friess, Rolf Breinbauer, Aleksandar Bijelic and Peter Macheroux Loop 6 and the β-hairpin flap are structural hotspots that determine cofactor specificity in the FMN-dependent family of ene-reductases Publikation in PURE anzeigen

Tanja Knaus, Peter Macheroux and Francesco G. Mutti Fus-SMO Publikation in PURE anzeigen

Michael Friess, Amit Singh Sahrawat, Bianca Kerschbaumer, Silvia Wallner, Ana Torvisco, Roland Fischer, Karl Gruber, Peter Macheroux and Rolf Breinbauer Asymmetric Synthesis of Chiral 2-Cyclohexenones with Quaternary Stereocenters via Ene-Reductase Catalyzed Desymmetrization of 2,5-Cyclohexadienones Publikation in PURE anzeigen

Bianca Kerschbaumer, Peter Macheroux and Aleksandar Bijelic Analysis of homodimer formation in 12-oxophytodienoate reductase 3 in solutio and crystallo challenges the physiological role of the dimer Publikation in PURE anzeigen

Aleksandar Bijelic, Bianca Kerschbaumer, Peter Macheroux and Hannah Gasser Unveiling the coenzyme specificity in ene-reducatses Publikation in PURE anzeigen

2023

Thomas Boehm, Cristina Martin-Higueras, Eva Friesser, Clara Zitta, Silvia Wallner, Adam Walli, Katarina Kovacevic, Holger Hubmann, Kristaps Klavins, Peter Macheroux, Bernd Hoppe and Bernd Jilma Simple, fast and inexpensive quantification of glycolate in the urine of patients with primary hyperoxaluria type 1 Publikation in PURE anzeigen

Oriol Gracia Carmona, Majd Lahham, Peter Poliak, Dominic Goj, Eva Maria Frießer, Silvia Wallner, Peter Macheroux and Chris Oostenbrink Understanding the riddle of amine oxidase flavoenzyme reactivity on the stereoisomers of N-methyl-dopa and N-methyl-tyrosine Publikation in PURE anzeigen

2022

Harald Podversnik, Shalinee Jha, Peter Macheroux and Rolf Breinbauer Design and synthesis of efficient fluororethylene-peptidomimetic inhibitors of dipeptidyl peptidase III (DPP3) Publikation in PURE anzeigen

Fatemeh Saadat, Peter Macheroux, Houshang Alizadeh and Seyed Hadi Razavi Economic purification of recombinant uricase by artificial oil bodies Publikation in PURE anzeigen

Reinmar Stefan Eggers and Peter Macheroux From Alcohol to Aldehyde: Characterization of Monolignol Oxidoreductases in Arabidopsis thaliana and Their Possible Involvement in the Extracellular Phenolics Pool Publikation in PURE anzeigen

Michael Frieß, Rolf Breinbauer, Kathrin Heckenbichler, Anna Katharina Schweiger, Lea Alexandra Brandner, Alexandra Binter, Marina Toplak, Peter Macheroux and Karl Gruber Small ring synthesis via ene-reductasemediated reductive cyclization Publikation in PURE anzeigen

Maria Degli Innocenti, Rolf Breinbauer, Katharina Fuchs, Aleksandar Bijelic and Peter Macheroux Studies towards the Developement of Small Molecule Inhibitors of Chorismate Synthase Publikation in PURE anzeigen

Katharina Fuchs, Aleksandar Bijelic and Peter Macheroux Investigating the inhibitory effect of azo-dyes on the activity of chorismate synthases from various organisms Publikation in PURE anzeigen

Katharina Fuchs, Aleksandar Bijelic and Peter Macheroux Chorismate synthase as drug target Publikation in PURE anzeigen

Bianca Kerschbaumer, Aleksandar Bijelic and Peter Macheroux Flavofun: Exploration of fungal flavoproteomes Publikation in PURE anzeigen

Eleni Skourti and Peter Macheroux In conversation with Peter Macheroux Publikation in PURE anzeigen

Bettina Eggbauer, Joerg H. Schrittwieser, Bianca Kerschbaumer, Peter Macheroux and Wolfgang Kroutil Regioselective Biocatalytic C4-Prenylation of Unprotected Tryptophan Derivatives Publikation in PURE anzeigen

2021

Igor Asanović, Emilia Strandback, Alena Kroupova, Djurdja Pasajlic, Anton Meinhart, Pai Tsung-Pin, Nemanja Djokovic, Dorothea Anrather, Thomas Schuetz, Marcin Józef Suskiewicz, Sirelin Sillamaa, Thomas Köcher, Rebecca Beveridge, Katarina Nikolic, Alexander Schleiffer, Martin Jinek, Markus Hartl, Tim Clausen, Josef Penninger, Peter Macheroux, Stefan Weitzer and Javier Martinez The oxidoreductase PYROXD1 uses NAD(P)+ as an antioxidant to sustain tRNA ligase activity in pre-tRNA splicing and unfolded protein response Publikation in PURE anzeigen

Jakov Ivkovic, Shalinee Jha, Christian Lembacher-Fadum, Johannes Puschnig, Prashant Kumar, Viktoria Reithofer, Karl Gruber, Peter Macheroux and Rolf Breinbauer Efficient Entropy-Driven Inhibition of Dipeptidyl Peptidase III by Hydroxyethylene Transition-State Peptidomimetics Publikation in PURE anzeigen

Bianca Kerschbaumer and Peter Macheroux Oxidative C-H activation for C-C bond formation: Characterization of EasC/EasE and comparison to CnsA/CnsD Publikation in PURE anzeigen

Katharina Fuchs, Aleksandar Bijelic and Peter Macheroux Investigating the inhibitory effect of azo-dyes on the activity of chorismate synthases from various organisms Publikation in PURE anzeigen

Marjeta Gregorc, Bettina Hierzberger, Grazia Malovan, Silvia Wallner and Peter Macheroux Understanding biochemical properties of glucose oxidase for enhanced sensor development Publikation in PURE anzeigen

Sami Ullah Khan, Silvia Wallner and Peter Macheroux Flavin cofactor modifications reveal effect on electron transfer in human electron transferring flavoprotein Publikation in PURE anzeigen

Julia Messenlehner, Michael Hetman, Adrian Tripp, Silvia Wallner, Peter Macheroux, Karl Gruber and Bastian Daniel The catalytic machinery of the FAD-dependent AtBBE-like protein 15 for alcohol oxidation Publikation in PURE anzeigen

2020

Emilia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Benjamin Bourgeois, Anja Högler, Daniel Waltenstorfer, Andreas Winkler, Klaus Zangger, Tobias Madl, Karl Gruber and Peter Macheroux A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro Publikation in PURE anzeigen

Reinmar Stefan Eggers, Alexandra Jammer, Karl Gruber, Peter Macheroux and Silvia Wallner Characterization of Monolignol Oxidoreductases from the Berberine Bridge Enzyme-like Protein Family in Arabidopsis thaliana Publikation in PURE anzeigen

Shalinee Jha, Ulrike Taschler, Oliver Domenig, Marko Poglitsch, Benjamin Bourgeois, Marion Pollheimer, Tobias Madl, Karl Gruber, Robert Zimmermann and Peter Macheroux Dipeptidyl peptidase 3 modulates the renin-angiotensin-aldosterone system Publikation in PURE anzeigen

Shalinee Jha, Robert C. Speth and Peter Macheroux The possible role of a bacterial aspartate β-decarboxylase in the biosynthesis of alamandine Publikation in PURE anzeigen

Sara Matić, Ivana Kekez, Marko Tomin, Ferenc Bogár, Filip Šupljika, Saša Kazazić, Maja Hanić, Shalinee Jha, Hrvoje Brkić, Benjamin Bourgeois, Tobias Madl, Karl Gruber, Peter Macheroux, Dubravka Matković-Čalogović, Mihaela Matovina and Sanja Tomić Binding of dipeptidyl peptidase III to the oxidative stress cell sensor Kelch-like ECH-associated protein 1 is a two-step process Publikation in PURE anzeigen

Shalinee Jha, Ulrike Taschler, Oliver Domenig, Marko Poglitsch, Benjamin Bourgeois, Marion Pollheimer, Lisa M Pusch, Grazia Malovan, Saša Frank, Tobias Madl, Karl Gruber, Robert Zimmermann and Peter Macheroux Dipeptidyl peptidase 3 modulates the renin-angiotensin system in mice Publikation in PURE anzeigen

Leen Assil-Companioni, Hanna C. Büchsenschütz, Dániel Solymosi, Nina G. Dyczmons-Nowaczyk, Kristin K.F. Bauer, Silvia Wallner, Peter MacHeroux, Yagut Allahverdiyeva, Marc M. Nowaczyk and Robert Kourist Engineering of NADPH Supply Boosts Photosynthesis-Driven Biotransformations Publikation in PURE anzeigen

Eveline Brodl, Alexandra Csamay, Christina Horn, Johannes Niederhauser, Hansjörg Weber and Peter Macheroux The impact of LuxF on light intensity in bacterial bioluminescence Publikation in PURE anzeigen

2019

Marina Toplak, Julia Brunner, Julia Schmidt and Peter Macheroux Biochemical characterization of human D-2-hydroxyglutarate dehydrogenase and two disease related variants reveals the molecular cause of D-2 hydroxyglutaric aciduria Publikation in PURE anzeigen

Marina Toplak, Julia Brunner, Chaitanya R. Tabib and Peter Macheroux Closing the gap Publikation in PURE anzeigen

Somayyeh Gandomkar, Etta Jost, Doris Loidolt, Alexander Swoboda, Mathias Pickl, Wael Elaily, Bastian Daniel, Marco W. Fraaije, Peter Macheroux and Wolfgang Kroutil Biocatalytic Enantioselective Oxidation of Sec-Allylic Alcohols with Flavin-Dependent Oxidases Publikation in PURE anzeigen

Karin Koch, Emilia Strandback, Shalinee Jha, Gesa Richter, Benjamin Bourgeois, Tobias Madl and Peter Macheroux Oxidative stress-induced structural changes in the microtubule-associated flavoenzyme Irc15p from Saccharomyces cerevisiae Publikation in PURE anzeigen

Paulo S.A. Bueno, Franciele A.V. Rodrigues-Vendramini, Marina Toplak, Peter Macheroux, Érika S. Kioshima and Flavio A.V. Seixas New inhibitors of chorismate synthase present antifungal activity against Paracoccidioides brasiliensis Publikation in PURE anzeigen

Linda Rehfeld, Eugenia Funk, Shalinee Jha, Peter Macheroux, Olle Melander and Andreas Bergmann Novel Methods for the Quantification of Dipeptidyl Peptidase 3 (DPP3) Concentration and Activity in Human Blood Samples Publikation in PURE anzeigen

Grazia Malovan, Ulrike Taschler, Jelena Gagic and Peter Macheroux Effect of DPP3 expression on oxidative stress in MEFs Publikation in PURE anzeigen

2018

Kathrin Heckenbichler, Anna Katharina Schweiger, Lea Alexandra Brandner, Alexandra Binter, Marina Toplak, Peter Macheroux, Karl Gruber and Rolf Breinbauer Asymmetric Reductive Carbocyclization Using Engineered Ene Reductases Publikation in PURE anzeigen

Kathrin Heckenbichler, Anna Katharina Schweiger, Lea Alexandra Brandner, Alexandra Binter, Marina Toplak, Peter Macheroux, Karl Gruber and Rolf Breinbauer Asymmetrische reduktive Carbocyclisierung durch modifizierte En‐Reduktasen Publikation in PURE anzeigen

Eveline Brodl, Johannes Niederhauser and Peter Macheroux In Situ Measurement and Correlation of Cell Density and Light Emission of Bioluminescent Bacteria Publikation in PURE anzeigen

Marina Toplak, Julia Brunner and Peter Macheroux Tight product binding is the key for efficient electron transfer from D-lactate dehydrogenase 2 to the electron transferring flavoprotein of Saccharomyces cerevisiae Publikation in PURE anzeigen

Eveline Brodl, Christina Horn, Johannes Niederhauser and Peter Macheroux LuxF and its various roles in bacterial bioluminescence Publikation in PURE anzeigen

Bastian Daniel, Julia Messenlehner, Jörg H Schrittwieser, Sabine Pils, Wolfgang Kroutil and Peter Macheroux The monolignol oxidoreductase AtBBE-like protein 15: Characterization, rational engineering and biocatalytic applications. Publikation in PURE anzeigen

Marina Toplak, Gertrud Wiedemann, Jelena Ulićević, Bastian Daniel, Sebastian N W Hoernstein, Jennifer Kothe, Johannes Niederhauser, Ralf Reski, Andreas Winkler and Peter Macheroux The single berberine bridge enzyme homolog of Physcomitrella patens is a cellobiose oxidase Publikation in PURE anzeigen

Naseem Iqbal, Jon D. Stewart, Peter Macheroux, Florian Rudroff and Marko D. Mihovilovic Novel concurrent redox cascades of (R)- and (S)-carvones enables access to carvo-lactones with distinct regio- and enantioselectivity Publikation in PURE anzeigen

Majd Lahham, Tea Pavkov-Keller, Michael Fuchs, Johannes Niederhauser, Gabriel Chalhoub, Bastian Daniel, Wolfgang Kroutil, Karl Gruber and Peter Macheroux Oxidative cyclization of N-methyl-dopa by a fungal flavoenzyme of the amine oxidase family Publikation in PURE anzeigen

Franciele Abigail Vilugron Rodrigues-Vendramini, Cidnei Marschalk, Marina Toplak, Peter Macheroux, Patricia de Souza Bonfim-Mendonca, Terezinha Inez Estivalet Svidzinski, Flavio Augusto Vicenter Seixas and Erika Seki Kioshima Promising New Antifungal Treatment Targeting Chorismate Synthase from Paracoccidioides brasiliensis Publikation in PURE anzeigen

2017

Eveline Brodl, Chaitanya Tabib and Peter Macheroux Bacterial bioluminescence: the in vitro formation of myrFMN Publikation in PURE anzeigen

Chanakan Tongsook, Johannes Niederhauser, Elena Kronegger, Grit Daniela Straganz and Peter Macheroux Leucine 208 in human histamine N-methyltransferase emerges as a hotspot for protein stability rationalizing the role of the L208P variant in intellectual disability Publikation in PURE anzeigen

Eveline Brodl, Jakov Ivkovic, Chaitanya Tabib, Rolf Breinbauer and Peter Macheroux Synthesis of α,β-unsaturated aldehydes as potential substrates for bacterial luciferases Publikation in PURE anzeigen

Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer-Augustin, Altijana Hromic, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Mink Daniel, Schürmann Martin, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica Publikation in PURE anzeigen

Chaitanya Tabib, Eveline Brodl and Peter Macheroux Evidence for the generation of myristylated FMN by bacterial luciferase Publikation in PURE anzeigen

Eveline Brodl, Stefan Schild and Peter Macheroux Genomic integration of luxF into the Vibrio harveyi lux operon Publikation in PURE anzeigen

Marina Toplak, Jelena Ulicevic, Bastian Daniel, Silvia Wallner and Peter Macheroux Studying the role of the only berberine bridge enzyme-like protein in Physcomitrella patens Publikation in PURE anzeigen

Marina Toplak, Gertrud Wiedemann, Jelena Ulicevic, Bastian Daniel, Sebastian Hoernstein, Jennifer Kothe, Ralf Reski, Andreas Winkler and Peter Macheroux The origin of the berberine bridge enzyme-like protein family in plants Publikation in PURE anzeigen

Kathrin Heckenbichler, Anna Katharina Schweiger, Karl Gruber, Peter Macheroux and Rolf Breinbauer New “old yellow enzyme”: a reductive C-C bond formation using engineered enoate reductase Publikation in PURE anzeigen

Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer, Hromic Altijana, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Daniel Mink, Martin Schürmann, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler Application of hydratases for flavour and fragrance synthesis Publikation in PURE anzeigen

Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer, Altijana Hromic, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Mink Daniel, Martin Schürmann, Silvia Wallner, Peter Macheroux, Harald Pichler and Karl Gruber Application of hydratases for flavor and fragrance synthesis Publikation in PURE anzeigen

Maximilian Aigner, Patricia Preissegger, Kurt Kalcher, Eda Mehmeti, Peter Macheroux, Dale Edmondson and Astrid Ortner Biosensor for the characterisation of hMAO B inhibitors and the quantification of selegiline Publikation in PURE anzeigen

Wolf Dieter Lienhart, Emilia Strandback, Venugopal Gudipati, Karin Koch, Alexandra Binter, Michael K. Uhl, David M. Rantasa, Benjamin Bourgeois, Tobias Madl, Klaus Zangger, Karl Gruber and Peter Macheroux Catalytic competence, structure and stability of the cancer-associated R139W variant of the human NAD(P)H Publikation in PURE anzeigen

Karin Koch, Altijana Hromic, Marija Sorokina, Emilia Strandback, Manuel Reisinger, Karl Gruber and Peter Macheroux Structure, biochemical and kinetic properties of recombinant Pst2p from Saccharomyces cerevisiae, a FMN-dependent NAD(P)H Publikation in PURE anzeigen

Igor Sabljic, Nevenka Meštrović Radan, Bojana Vukelić, Peter Macheroux, Karl Gruber, Marija Luić and Marija Abramic Crystal structure of dipeptidyl peptidase III from the human gut symbiont Bacteroides theraiotaomicron Publikation in PURE anzeigen

Shalinee Jha, Jakov Ivkovic, Prashant Kumar, Ulrike Taschler, Robert Zimmermann, Karl Gruber, Rolf Breinbauer and Peter Macheroux Kinetic studies of inhibition of hDPP3 by hydroxyethylene transition state peptidomimetics Publikation in PURE anzeigen

Shalinee Jha, Jakov Ivkovic, Prashant Kumar, Ulrike Taschler, Robert Zimmermann, Karl Gruber, Rolf Breinbauer and Peter Macheroux Peptidomimetic transition state inhibitors as chemical probes to explore in-vivo role of dipeptidyl peptidase 3 Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Anja Högler, Daniel Waltenstorfer, Andreas Winkler, Klaus Zangger, Nadia Dandachi, Ellen Heitzer, Benjamin Bourgeois, Tobias Madl, Rolf Breinbauer, Karl Gruber and Peter Macheroux Stabilization of a cancer associated variant of human NQO1 by the use of small-molecular chaperones Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Anja Högler, Andreas Winkler, Klaus Zangger, Nadia Dandachi, Ellen Heitzer, Benjamin Bourgeois, Tobias Madl, Rolf Breinbauer, Karl Gruber and Peter Macheroux Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones Publikation in PURE anzeigen

2016

Chanakan Tongsook, Michael K. Uhl, Frank Jankowitsch, Matthias Mack, Karl Gruber and Peter Macheroux Structural and kinetic studies on RosA, the enzyme catalyzing the methylation of 8-demethyl-8-amino-D-riboflavin to the antibiotic roseoflavin Publikation in PURE anzeigen

Prashant Kumar, Viktoria Reithofer, Manuel Reisinger, Tea Pavkov-Keller, Silvia Wallner, Peter Macheroux and Karl Gruber Substrate complexes of human dipeptidyl peptidase III reveal the mechanism of enzyme inhibition Publikation in PURE anzeigen

Peter Andreas Augustin, Michael Haider, Anika Stracke, Nathalie Meier-Allard, Andreas Meinitzer, Beate Rinner, Peter Macheroux and Robert Fuchs The role of the enzyme dimethylglycine dehydrogenase in sarcosine metabolism of human prostate cancer cell lines Publikation in PURE anzeigen

Karin Koch, Altijana Hromic, Marija Sorokina, Manuel Reisinger, Karl Gruber and Peter Macheroux The flavodoxin-like proteins Pst2 and Ycp4 from Saccharomyces cerevisiae belong to the FMN-dependent NAD(P)H:quinone oxidoreductases Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Venugopal Gudipati and Peter Macheroux Investigation of the Reasons for the Destabilization of a Natural Variant of NAD(P)H:quinone oxidoreductase 1 Publikation in PURE anzeigen

Chanakan Tongsook, Michael K Uhl, Frank Jankowitsch, Matthias Mack, Karl Gruber and Peter Macheroux Structure and mechanism of RosA, the enzyme catalysing the methylation of 8-demethyl-8-amino-D-riboflavin to the antibiotic roseoflavin Publikation in PURE anzeigen

Eveline Brodl, Chaitanya Tabib, Jakov Ivkovic, Rolf Breinbauer and Peter Macheroux Role of enzymes involved in Bacterial Bioluminescence Publikation in PURE anzeigen

Bastian Daniel, Silvia Wallner, Barbara Steiner, Gustav Oberdorfer, Prashant Kumar, Eric van der Graaff, Thomas Roitsch, Christoph W Sensen, Karl Gruber and Peter Macheroux Structure of a Berberine Bridge Enzyme-Like Enzyme with an Active Site Specific to the Plant Family Brassicaceae Publikation in PURE anzeigen

Eveline Brodl, Chaitanya Tabib and Peter Macheroux New insights in bacterial bioluminescence: in vitro myrFMN production Publikation in PURE anzeigen

Kathrin Heckenbichler, Anna Katharina Schweiger, Alexandra Binter, Peter Macheroux, Karl Gruber and Rolf Breinbauer New “old yellow enzyme”: Reductive C-C bond formation using an engineered enoate reductase Publikation in PURE anzeigen

Bastian Daniel, Peter Macheroux, Silvia Wallner, Barbara Steiner, Karl Gruber and Tea Pavkov-Keller The family of berberine bridge enzyme-like proteins from Arabidopsis thaliana Publikation in PURE anzeigen

Bastian Daniel, Barbara Steiner, Tea Pavkov-Keller, Karl Gruber, Eric van der Graaff, Thomas Roitsch, Silvia Wallner and Peter Macheroux Berberine bridge enzyme-like proteins: a multi-gene family from vascular plants Publikation in PURE anzeigen

Marina Toplak, Bastian Daniel, Silvia Wallner, Gertrud Wiedemann, Ralf Reski and Peter Macheroux The Berberine bridge enzyme-like enzyme from Physcomitrella patens Publikation in PURE anzeigen

Marina Toplak, Silvia Wallner and Peter Macheroux EasC and EasE – what is their role in chanoclavine I formation? Publikation in PURE anzeigen

Marina Toplak, Bastian Daniel, Silvia Wallner, Gertrud Wiedemann, Ralf Reski and Peter Macheroux PpBBE – the ancestor of berberine bridge enzyme-like enzymes in plants? Publikation in PURE anzeigen

Barbara Steiner, Bastian Daniel, Silvia Wallner, Karl Gruber, Tea Pavkov, Eric van der Graaff, Thomas Roitsch and Peter Macheroux Monolignol oxidoreductases from the berberine bridge enzyme-like protein family Publikation in PURE anzeigen

Barbara Steiner, Bastian Daniel, Alexandra Jammer, Silvia Wallner, Karl Gruber, Tea Pavkov, Eric van der Graaff, Maria Müller , Thomas Roitsch and Peter Macheroux Function of monolignol oxidoreductases from the berberine bridge enzyme-like protein family in Arabidopsis thaliana Publikation in PURE anzeigen

Eveline Brodl, Chaitanya Tabib and Peter Macheroux In vitro bioluminescence: an enzyme cascade producing myrFMN Publikation in PURE anzeigen

Bastian Daniel, Sabine Pils, Barbara Steiner, Silvia Wallner, Tea Pavkov-Keller, Karl Gruber, Jörg Schrittwieser, Michael Fuchs, Wolfgang Kroutil and Peter Macheroux Berberine bridge enzyme-like proteins: From characterization to application Publikation in PURE anzeigen

Karin Koch and Peter Macheroux The protective/regulative role of the antioxidant enzyme Irc15 on the microtubule network of S. cerevisiae Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic, Jakob Pletz, Christoph Köberl, Venugopal Gudipati, Karl Gruber, Rolf Breinbauer and Peter Macheroux Novel insights into structural destabilization of a cancer associated variant of human NQO1 Publikation in PURE anzeigen

Eveline Brodl, Chaitanya Tabib and Peter Macheroux Towards in vitro bioluminescence: exploiting bacterial luciferases Publikation in PURE anzeigen

Marina Toplak, Jelena Ulićević, Bastian Daniel, Silvia Wallner and Peter Macheroux PpBBE-studying the origine of BBE-like enzymes in plants Publikation in PURE anzeigen

Sabine Pils, Kordula Schnabl, Silvia Wallner, Marko Kljajic, Nina Kupresanin, Rolf Breinbauer, Jörg Schrittwieser, Michael Fuchs, Wolfgang Kroutil, Bastian Daniel and Peter Macheroux Characterization of the monolignol oxidoreductase AtBBE-like protein 15 L182V for biocatalytic applications Publikation in PURE anzeigen

Peter Augustin, Altijana Hromic, Tea Pavkov-Keller, Karl Gruber and Peter Macheroux Structure and biochemical properties of recombinant human dimethylglycine dehydrogenase and comparison to the disease-related H109R variant Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Christoph Köberl, Altijana Hromic, Jakob Pletz, Venugopal Gudipati, Karl Gruber, Rolf Breinbauer and Peter Macheroux Towards understanding the structural destabilization of a cancer associated variant of human NQO1 Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Christoph Köberl, Altijana Hromic, Jakob Pletz, Venugopal Gudipati, Klaus Zangger, Karl Gruber, Rolf Breinbauer and Peter Macheroux On the way to rescue the stability and activity of a cancer associated variant of human NQO1 Publikation in PURE anzeigen

Peter Macheroux Bacterial bioluminescence: the mystery of myristylated flavins Publikation in PURE anzeigen

Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer-Augustin, Hromic Altijana, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Mink Daniel, Martin Schurmann, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica Publikation in PURE anzeigen

Peter Macheroux, Wolf-Dieter Lienhart, Silvia Wallner, Maximilian Aigner, Astrid Ortner, Kurt Kalcher and Dale Edmondson Determination of Total Monoamines in Rat Brain via Nanotubes Based Human Monoamine Oxidase B Biosensor Publikation in PURE anzeigen

Shalinee Jha, Ulrike Taschler, Jakov Ivkovic, Rolf Breinbauer, Karl Gruber, Robert Zimmermann and Peter Macheroux Characterization and therapeutic exploitation of human dipeptidyl peptidase III (hDPPIII): an enzyme with multifaceted functionality Publikation in PURE anzeigen

Shalinee Jha, Jakov Ivkovic, Ulrike Taschler, Prashant Kumar, Robert Zimmermann, Karl Gruber, Rolf Breinbauer and Peter Macheroux Targeting human dipeptidyl peptidase III (hDPPIII): a therapeutic potential for safer pain management Publikation in PURE anzeigen

2015

Maximilian Aigner, Dietlind Telsnig, Kurt Kalcher, Christian Teubl, Peter Macheroux, Silvia Wallner, Dale Edmondson and Astrid Ortner Amperometric biosensor for total monoamines using a glassy carbon paste electrode modified with human monoamine oxidase B and manganese dioxide particles Publikation in PURE anzeigen

Wolf-Dieter Lienhart, Emilia Sofia Strandback, Venugopal Gudipati, Michael Karl Uhl, Alexandra Binter, Klaus Zangger, Rolf Breinbauer, Karl Gruber and Peter Macheroux NAD(P)H:quinone oxidoreductase 1 as a crucial enzyme in human cancer development and treatment Publikation in PURE anzeigen

Wolf-Dieter Lienhart, Emilia Sofia Strandback, Klaus Zangger, Rolf Breinbauer, Karl Gruber and Peter Macheroux NAD( P)H:quinone oxidoreductase 1 as a crucial enzyme in human cancer development and treatment Publikation in PURE anzeigen

Thomas Bergner, Chaitanya Tabib, Andreas Winkler, Steve Stipsits, Heidemarie Kayer, John Lee, Stephen Mayhew, Jonathan Malthouse, Franz Müller, Karl Gruber and Peter Macheroux Structural and biochemical properties of LuxF from Photobacterium leiognathi Publikation in PURE anzeigen

Altijana Hromic, Nina Jajcanin-Jozic, Prashant Kumar, Silvia Wallner, Peter Macheroux, Marija Abramic and Karl Gruber Structural and biochemical characterization of dipeptidyl peptidase III from Porphyromonas gingival is Publikation in PURE anzeigen

Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer, Altijana Hromic, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Daniel Mink, Martin Schürmann, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler ON THE REACTION MECHANISM OF THE ELIZABETHKINGIA MENINGOSEPTICA OLEATE HYDRATASE Publikation in PURE anzeigen

Shalinee Jha, Peter Macheroux, Jakov Ivkovic, Ulrike Taschler, Prashant Kumar, Karl Gruber and Robert Zimmermann Characterization of DPPIII knockout mice Publikation in PURE anzeigen

Eveline Brodl, Chaitanya Tabib, Jakov Ivkovic, Rolf Breinbauer and Peter Macheroux The mystery of myrFMN production by bioluminescent bacteria Publikation in PURE anzeigen

Chaitanya Tabib, Eveline Brodl, Thomas Bergner, Jakov Ivkovic, Silvia Wallner, Rolf Breinbauer and Peter Macheroux A luciferous surprise: A new natural aldehyde substrate for bacterial bioluminescence Publikation in PURE anzeigen

Karin Koch and Peter Macheroux Biochemical and structural characterization of the microtubule-associated protein Irc15 Publikation in PURE anzeigen

Jakov Ivkovic, Prashant Kumar, Silvia Wallner, Peter Macheroux, Karl Gruber and Rolf Breinbauer Structure-Based Design and Synthesis of Inhibitors of Dipeptidylpeptidase III (DPP3) Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Venugopal Gudipati and Peter Macheroux Structural and Biochemical Investigation of New NAD(P)H:quinone oxidoreductase 1 (NQO1) P187X Variants Publikation in PURE anzeigen

Altijana Hromic, Prashant Kumar, K.M.P. Das, Nina Jajcanin-Jozic, Silvia Wallner, Marija Abramic, Peter Macheroux, Monika Oberer and Karl Gruber Structural and biochemical characterization of dipeptidyl peptidase III from Porphyromonas gingival is Publikation in PURE anzeigen

Thomas Bergner, Tea Pavkov-Keller, Katharina Kreuzer, Jakob Kowaliuk, Markus Plank, Kathrin Runggatscher, Nikolaus G. Turrini, Benjamin Zucol, Silvia Wallner, Kurt Faber, Karl Gruber and Peter Macheroux Anthranoyl-CoA monooxygenase/reductase from Azoarcus evansii possesses both FMN and FAD in two distinct and independent active sites Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Venugopal Gudipati and Peter Macheroux Structural and biochemical investigation of new NAD(P)H:quinone oxidoreductase 1 (NQO1) P187X variants Publikation in PURE anzeigen

Igor Sabljic, Karl Gruber, Peter Macheroux, Marjia Abramic and Marjia Luic The first X-ray structure of prokaryotic dipeptidyl peptidase III Publikation in PURE anzeigen

Bastian Daniel, Barbara Steiner, Tea Pavkov-Keller, Andela Dordic, Alexander Gutmann, Bernd Nidetzky, Christoph Wilhelm Sensen, Eric van der Graaff, Silvia Wallner, Karl Gruber and Peter Macheroux The berberine bridge enzyme-like superfamily: A multi gene family involved in lignification, drought and pathogen response Publikation in PURE anzeigen

Kathrin Heckenbichler, Alexandra Binter, Tea Pavkov-Keller, Georg Steinkellner, Kerstin Steiner, Karl Gruber and Peter Macheroux Identification and characterization of Tth-X and Pho-Y, novel members of the OYE family Publikation in PURE anzeigen

Eveline Brodl, Chaitanya Tabib, Thomas Bergner, Jakov Ivkovic, Rolf Breinbauer and Peter Macheroux The role of luciferase in myrFMN formation Publikation in PURE anzeigen

Bastian Daniel, Tea Pavkov-Keller, Barbara Steiner, Angela Dodic, Alexander Gutmann, Bernd Nidetzky, Christoph Wilhelm Sensen, Eric van der Graaff, Silvia Wallner, Karl Gruber and Peter Macheroux Oxidation of monolignols by members of the berberine bridge enzyme family suggests a role in plant cell wall metabolism Publikation in PURE anzeigen

Marie Bernkopf, Christian Windpassinger, W Kranewitter, S Schwarz, M Baumgartner, H Duba, V Pilshofer, E Kugler, Chanakan Tongsook, Peter Macheroux, John Vincent and G Webersinke Methyltransferases and intellectual disability - an NGS-Gene-Panel approach Publikation in PURE anzeigen

Christian Lembacher-Fadum, Jakov Ivkovic, Shalinee Jha, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III Publikation in PURE anzeigen

Chanakan Tongsook, Michael K Uhl, Karl Gruber and Peter Macheroux Exploration of the catalytic function and structure of N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA) Publikation in PURE anzeigen

Somayyeh Gandomkar, Eva-Maria Fischereder, Jörg Schrittwieser, Silvia Wallner, Zohreh Habibi, Peter Macheroux and Wolfgang Kroutil Enantioselective oxidative aerobic dealkylation of N-ethylbenzylisoquinolines employing the berberine bridge enzyme Publikation in PURE anzeigen

Jakov Ivkovic, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and Synthesis of Inhibitors of DPP3 Publikation in PURE anzeigen

Domen Zafred, Barbara Steiner, Andrea R. Teufelberger, Altijana Hromic, Andrew P. Karplus, Christopher J. Schofield, Silvia Wallner and Peter Macheroux Rationally engineered flavin-dependent oxidase reveals steric control of dioxygen reduction Publikation in PURE anzeigen

Samayyeh Gandomkar, Eva-Maria Fischereder, Joerg H. Schrittwieser, Silvia Wallner, Zohreh Habibi, Peter Macheroux and Wolfgang Kroutil Enantioselektive oxidative aerobe Desalkylierung von N-Ethylbenzyl-isochinolinen mithilfe des Berberin-Brücken-Enzyms Publikation in PURE anzeigen

Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer, Hromic Altijana, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Mink Daniel, Schürmann Martin, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler Structure-based mechanism of oleate hydratase from Elizabethkingia meningoseptica Publikation in PURE anzeigen

Prashant Kumar, Henning Seidel, Young-Hwa Song, Christian Hübner, Peter Macheroux and Karl Gruber Solution studies of human dipeptidyl peptidase III (hDPPIII) reveals dynamic equilibrium between different substrates Publikation in PURE anzeigen

Bastian Daniel, Tea Pavkov-Keller, Barbara Steiner, Andela Dordic, Alexander Gutmann, Bernd Nidetzky, Christoph Wilhelm Sensen, Eric van der Graaff, Silvia Wallner, Karl Gruber and Peter Macheroux Structural and biochemical characterization of a monolignol oxidoreductase from A. thaliana implies a link between the berberine bridge enzyme-like family and cell wall metabolism Publikation in PURE anzeigen

Shalinee Jha, U Taschler, Jakov Ivkovic, Prashant Kumar, Karl Gruber, Robert Zimmermann and Peter Macheroux Characterization of DPP III knockout mice Publikation in PURE anzeigen

Abolfazl Heidari, Chanakan Tongsook, Reza Najafipour, Luciana Musante, Nasium Vasli, Masoud Garshasbi, Hao Hu, Kirti Mittal, Amy McNaughton, Kumudesh Sritharan, Melissa Hudson, Henning Stehr, Saeid Talebi, Mohammad Moradi, Hossein Darvish, Muhammad Arshad Rafiq, Hossein Mozhdehipanah, Christian Windpassinger, Gabriele Gillessen-Kaesbach, Andreas Tzschach, Iltaf Ahmed, Anna Mikhailov, James Stavropoulos, Melissa Carter, Soraya Keshavarz, Muhammad Ayub, Hossein Najmabadi, Xudong Liu, Hans Hilger Ropers, Peter Macheroux and John Vincent Mutations in the histamine N-methyltransferase gene, HNMT, are associated with non-syndromic autosomal recessive intellectual disability Publikation in PURE anzeigen

Karin Koch and Peter Macheroux Biochemical and structural characterization of the microtubule-associated protein Irc15 Publikation in PURE anzeigen

Peter Andreas Augustin, Eva Gerstmann, Altijana Hromic, Karl Gruber and Peter Macheroux Biochemical investigations on the human dimethylglycine dehydrogenase Publikation in PURE anzeigen

Shalinee Jha, Ulrike Taschler, Jakov Ivkovic, Rolf Breinbauer, Robert Zimmermann and Peter Macheroux Characterization and therapeutic potential of DPP III knockout mice Publikation in PURE anzeigen

2014

Wolf-Dieter Lienhart, Venugopal Gudipati, Michael K. Uhl, Alexandra Binter, Sergio Pulido, Robert Saf, Klaus Zangger, Karl Gruber and Peter Macheroux Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase Publikation in PURE anzeigen

Peter Andreas Augustin, Eva Gerstmann, Altijana Hromic, Karl Gruber and Peter Macheroux Biochemical investigations on recombinant human dimethlyglycine dehydrogenase Publikation in PURE anzeigen

Jörg Schrittwieser, B. Groenendaal, Verena Resch, D. Ghislieri, Silvia Wallner, E. Fischereder, E. Fuchs, B. Grischek, J. Sattler, Peter Macheroux, Nick J. Turner and Wolfgang Kroutil Transformation of rac-benzylisoquinolines into (S)-berberines by simultaneous bio-oxidative kinetic resolution and stereoinversion Publikation in PURE anzeigen

Tea Pavkov-Keller, Alexandra Binter, Georg Steinkellner, Christian C. Gruber, Kerstin Steiner, Christoph Winkler, Helmut Schwab, Kurt Faber, Peter Macheroux and Karl Gruber Structural and biochemical characterization of two novel enzymes with promiscuous ene-reductase activity Publikation in PURE anzeigen

Chaitanya Tabib, Thomas Bergner, Silvia Lang, Karl Gruber, Ellen Zechner and Peter Macheroux A luciferous surprise: A new natural aldehyde substrate for bacterial bioluminescence Publikation in PURE anzeigen

Chanakan Tongsook, Christian Windpassinger, John B. Vincent and Peter Macheroux Effect of a single amino acid exchange in human histamine N-methyltransferase Publikation in PURE anzeigen

Wolf-Dieter Lienhart, Emilia Sofia Strandback, Venugopal Gudipati, Michael K. Uhl, Alexandra Binter, Sergio Pulido, Klaus Zangger, Karl Gruber and Peter Macheroux Insight into the structural behaviour of a natural variant of NAD(P)H:quinone oxidoreductase 1 (NQO1) Publikation in PURE anzeigen

Georg Steinkellner, Christian C. Gruber, Tea Pavkov-Keller, Alexandra Binter, Kerstin Steiner, Christoph Winkler, Andrzej Lyskowski, Orsolya Schwamberger, Monika Oberer, Helmut Schwab, Kurt Faber, Peter Macheroux and Karl Gruber Identification of promiscuous ene-reductase activity by mining structural databases using active site constellations Publikation in PURE anzeigen

Julia Koop, Stefanie Monschein, E. Pauline Macheroux, Tanja Knaus and Peter Macheroux Determination of free and bound riboflavin in cow's milk using a novel flavin-binding protein Publikation in PURE anzeigen

Chanakan Tongsook, Michael K. Uhl, Karl Gruber, Matthias Mack and Peter Macheroux Exploration of the catalytic function and structure of N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA) Publikation in PURE anzeigen

Wolf-Dieter Lienhart, Emilia Sofia Strandback, Venugopal Gudipati, Michael K. Uhl, Alexandra Binter, Sergio Pulido, Klaus Zangger, Karl Gruber and Peter Macheroux Insight into the structural behavior of a natural variant of NAD(P)H:quinone oxidoreductase 1 (NQO1) Publikation in PURE anzeigen

Domen Zafred, Barbara Steiner, Andrea R. Teufelberger, Bastian Daniel, Altijana Hromic, Christopher J. Schofield, Silvia Wallner and Peter Macheroux Engineered oxidase reveals steric control of oxygen reduction Publikation in PURE anzeigen

Venugopal Gudipati, Karin Koch, Wolf-Dieter Lienhart and Peter Macheroux The flavoproteome of the yeast Saccharomyces cerevisiae Publikation in PURE anzeigen

Marie Bernkopf, Gerald Webersinke, Chanakan Tongsook, Chintan N. Koyani, Muhammed Arshad, Muhammed Ayaz, Doris Müller, Christian Enzinger, Muhammed Aslam, Farooq Naeem, Kurt Schmidt, Karl Gruber, Michael R. Speicher, Ernst Malle, Peter Macheroux, Muhammed Ayub, John B. Vincent, Christian Windpassinger and Hans-Christoph Duba Disruption of the methyltransferase-like 23 gene METTL23 causes mild autosomal recessive intellectual disability Publikation in PURE anzeigen

Jörg H. Schrittwieser, Bas Groenendaal, Verena Resch, Diego Ghislieri, Silvia Wallner, Eva-Maria Fischereder, Elisabeth Fuchs, Barbara Grischek, Johann H. Sattler, Peter Macheroux, Nicholas J. Turner and Wolfgang Kroutil Deracemization by Simultaneous Bio-oxidative Kinetic Resolution and Stereoinversion Publikation in PURE anzeigen

Jörg H. Schrittwieser, Bas Groenendaal, Verena Resch, Diego Ghislieri, Silvia Wallner, Eva-Maria Fischereder, Elisabeth Fuchs, Barbara Grischek, Johann H. Sattler, Peter Macheroux, Nicholas J. Turner and Wolfgang Kroutil Deracemisierung durch simultane bio-oxidative Racematspaltung und Stereoinversion Publikation in PURE anzeigen

Tanja Knaus, Michael K. Uhl, Stefanie Monschein, Sabrina Moratti, Karl Gruber and Peter Macheroux Structure and stability of an unusual zinc-binding protein from Bacteroides thetaiotaomicron Publikation in PURE anzeigen

Chaitanya Tabib, Thomas Bergner, Silvia Lang, Karl Gruber, Ellen Zechner and Peter Macheroux Mechanistic Understanding of the bacterial bioluminescence Publikation in PURE anzeigen

G. Webersinke, Marie Bernkopf, Chanakan Tongsook, C. N. Koyani, M. Arshad, M. Ayaz, D. Müller, C. Enzinger, M. Aslam, F. Naeem, M. Speicher, E. Malle, Peter Macheroux, M. Ayub, John B. Vincent, Christian Windpassinger and H. C. Duba Disruption of the methyltransferase-like 23 gene METTL23 causes mild autosomal recessive intellectual disability Publikation in PURE anzeigen

Bastian Daniel, Barbara Steiner, Silvia Wallner, Tea Pavkov-Keller, Karl Gruber and Peter Macheroux Role of berberine bridge enzyme as a novel player in lignin biosynthesis Publikation in PURE anzeigen

Chaitanya Tabib, Thomas Bergner, Silvia Lang, Karl Gruber, Ellen Zechner and Peter Macheroux Mechanistic understanding of the bacterial bioluminescence Publikation in PURE anzeigen

Emilia Sofia Strandback, Wolf-Dieter Lienhart, Venugopal Gudipati, Michael K. Uhl, Alexandra Binter, Sergio Pulido, Klaus Zangger, Karl Gruber and Peter Macheroux Insight into the structural behaviour of a natural variant of NAD(P)H:quinone oxidoreductase 1 (NQO1) Publikation in PURE anzeigen

Chanakan Tongsook, Christian Windpassinger, John B. Vincent and Peter Macheroux Effect of a single amino acid exchange in human histamine N-methyltransferase Publikation in PURE anzeigen

Karin Koch, Johannes Repelnig and Peter Macheroux New insights in flavodoxin-like proteins from S. cerevisiae Publikation in PURE anzeigen

Silvia Wallner, Bastian Daniel, Barbara Steiner, Karl Gruber and Peter Macheroux The family of BBE-like enzymes in the plant kingdom Publikation in PURE anzeigen

Barbara Steiner, Bastian Daniel, Silvia Wallner, Karl Gruber and Peter Macheroux Structure and function of bicovalent flavoenzymes from Arabidopsis thaliana Publikation in PURE anzeigen

Chaitanya Tabib, Thomas Bergner, Silvia Lang, Karl Gruber, Ellen Zechner and Peter Macheroux Mechanistic understanding of the bacterial bioluminescence International Symposium on Bioluminescence and Chemiluminescence 99-99 Publikation in PURE anzeigen

Prashant Kumar, Y Song, C. Hübner, Karl Gruber and Peter Macheroux Investigating conformational heterogeneity in human DPPIII through single molecule FRET and MD simulation Publikation in PURE anzeigen

Peter Macheroux, Bastian Daniel, Barbara Steiner, Domen Zafred, Altijana Hromic, Silvia Wallner and Karl Gruber Functional and structural characterisation of BBE-like enzymes in plants Publikation in PURE anzeigen

Bastian Daniel, Silvia Wallner, Altijana Hromic, Barbara Steiner, Prashant Kumar, Karl Gruber and Peter Macheroux Structural and phylogenetic analysis of putative flavin-dependent oxidases from Arabidopsis thaliana Publikation in PURE anzeigen

Wolf-Dieter Lienhart, Venugopal Gudipati, Michael K. Uhl, Alexandra Binter, Sergio A. Pulido, Robert Saf, Klaus Zangger, Karl Gruber and Peter Macheroux Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase1 Publikation in PURE anzeigen

2013

Bianca Derrer, Peter Macheroux and Barbara Kappes The shikimate pathway in apicomplexan parasites: Implications for drug development Publikation in PURE anzeigen

Prashant Kumar, Gustavo A. Bezerra, Elena Dobrovetsky, Roland Viertlmayer, Alexandra Binter, Maria Abramic, Peter Macheroux, Sirano Dhe-Paganon and Karl Gruber Entropy-driven binding of an ovoid peptide induces a large domain motion in human DPPIII Publikation in PURE anzeigen

Chaitanya Tabib, Thomas Bergner, Silvia Lang, Karl Gruber, Ellen Zechner and Peter Macheroux Mechanistic understanding of the bacterial bioluminescence Publikation in PURE anzeigen

Thomas Bergner, Tea Pavkov-Keller, Katharina Lukas, Jakob Kowaliuk, Markus Plank, Karl Gruber and Peter Macheroux Structural characterization of 2-aminobenzoyl-CoA monooxygenase/reductase from Azoarcus evansii regarding its substrate binding ability Publikation in PURE anzeigen

Wolf-Dieter Lienhart, Venugopal Gudipati and Peter Macheroux The human flavoproteome Publikation in PURE anzeigen

Chanakan Tongsook, Marie Bernkopf, C. Windpassinger and Peter Macheroux Exploration of the function of human methyltransferase like 23 (METTL23) Publikation in PURE anzeigen

Desiree Pressnitz, Christine S. Fuchs, Johann H. Sattler, Tanja Knaus, Peter Macheroux, Francesco G. Mutti and Wolfgang Kroutil Asymmetric amination of tetralone and chromanone derivatives employing omega-transaminases Publikation in PURE anzeigen

Michael Toesch, Markus Schober, Tanja Knaus, Kurt Faber and Peter Macheroux Development of stereocomplentary sec-alkylsulfatases Publikation in PURE anzeigen

Chaitanya Tabib, Thomas Bergner, Silvia Lang, Karl Gruber, Ellen Zechner and Peter Macheroux Mechanistic understanding of the bacterial bioluminescence Publikation in PURE anzeigen

Thomas Bergner, Tea Pavkov-Keller, Jakob Kowaliuk, Markus Plank, Karl Gruber and Peter Macheroux Substrate binding to 2-aminobenzoyl-CoA monooxygenase/reductase from Azoarcus evansii Publikation in PURE anzeigen

Markus Schober, Michael Toesch, Tanja Knaus, Gernot Strohmeier, Bert van Loo, Michael Fuchs, Florian Hollfelder, Peter Macheroux and Kurt Faber One-pot deracemization of sec-alcohols: enantioconvergent enzymatic hydrolysis of alkyl sulfates using stereo complementary sulfatases Publikation in PURE anzeigen

Karin Koch, Karin Athenstaedt, Venugopal Gudipati and Peter Macheroux A novel role for the yeast bZIP transcription factor Yap4p in the regulation of sterol biosynthesis Publikation in PURE anzeigen

Markus Schober, Michael Toesch, Tanja Knaus, Gernot Strohmeier, Bert van Loo, Michael Fuchs, Florian Hollfelder, Peter Macheroux and Kurt Faber One-Pot Deracemization of sec-Alcohols: Enantioconvergent Enzymatic Hydrolysis of Alkyl Sulfates Using Stereocomplementary Sulfatases Publikation in PURE anzeigen

Jakov Ivkovic, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and synthesis of inhibitors of dipeptidyl peptidase-III Publikation in PURE anzeigen

Alexandra Binter, Tea Pavkov-Keller, Georg Steinkellner, Kerstin Steiner, Karl Gruber and Peter Macheroux Enzymatic characterization of two novel enzymes with enone-reductase activity Publikation in PURE anzeigen

Silvia Wallner, Bastian Daniel, Domen Zafred, Altijana Hromic, Barbara Steiner, Prashant Kumar, Karl Gruber and Peter Macheroux Structure and function of bicovalent flavoenzymes from Arabidopsis thaliana Publikation in PURE anzeigen

Georg Steinkellner, Christian Gruber, Kerstin Steiner, C. Winkler, Tea Pavkov-Keller, Alexandra Binter, A. Lyskowski, O. Schwamberger, Monika Oberer, Helmut Schwab, Kurt Faber, Peter Macheroux and Karl Gruber Novel enone-reductases identified by database mining for catalytic promiscuity Publikation in PURE anzeigen

Barbara Steiner, Bastian Daniel, Silvia Wallner, Domen Zafred, Altijana Hromic, Prashant Kumar, Karl Gruber and Peter Macheroux Structure and function of bicovalent flavoenzymes from Arabidopsis thaliana Publikation in PURE anzeigen

Gustav Oberdorfer, Alexandra Binter, Silvia Wallner, Katharina Durchschein, Melanie Hall, Kurt Faber, Peter Macheroux and Karl Gruber The structure of glycerol trinitrate reductase NerA from Agrobacterium radiobacter reveals the molecular reason for nitro- and ene-reductase activity in OYE homologues Publikation in PURE anzeigen

Wolf-Dieter Lienhart, Venugopal Gudipati, Michael K. Uhl, Klaus Zangger, Karl Gruber and Peter Macheroux The role of NAD(P)H:quinone oxidoreductase 1 in human cancer development Publikation in PURE anzeigen

Simone Langer, Shinobu Nakanishi, Tilo Mathes, Tanja Knaus, Alexandra Binter, Peter Macheroux, Tomoko Mase, Takuya Miyakawa, Masaru Tanokura and Matthias Mack The flavoenzyme azobenzene reductase AzoR from Escherichia coli binds roseoflavin mononucleotide (RoFMN) with high affinity and is less active in its RoFMN form Publikation in PURE anzeigen

Peter Macheroux, Venugopal Gudipati, Michael K. Uhl, Klaus Zangger, Karl Gruber and Wolf-Dieter Lienhart The role of NAD(P)H:quinone oxidoreductase 1 (NQO1) in human cancer development Publikation in PURE anzeigen

Chanakan Tongsook, M. Bernkopf, C Windpassinger and Peter Macheroux Exploration of the function of human methyltransferase like 23 (METTL23) Publikation in PURE anzeigen

Silvia Wallner, Andreas Winkler, Corinna Dully, Stefanie Horvath, Rosemarie Trenker, Karl Gruber and Peter Macheroux Further insights into the bicovalent flavinylation of berberine bridge enzyme Proceedings of the 17th International Symposium on Flavins and Flavoproteins 133-138 Publikation in PURE anzeigen

Joerg H. Schrittwieser, Verena Resch, Eva-Maria Fischereder, Alejandro Orden, Johann Sattler, Wolf-Dieter Lienhart, Silvia Wallner, Karl Gruber, Peter Macheroux and Wolfgang Kroutil Chemo-enzymatic access to novel berbine derivatives employing the berberine bridge enzyme Proceedings of the 17th International Symposium on Flavins and Flavoproteins 129-132 Publikation in PURE anzeigen

Katharina Durchschein, Klaus Zangger, Peter Macheroux, Silvia Wallner and Kurt Faber Unusual pathways in the reductive biotransformation of nitro-compounds catalyzed by flavoenzymes Proceedings of the 17th International Symposium on Flavins and Flavoproteins 437-451 Publikation in PURE anzeigen

Peter Macheroux, Prashant Kumar, Gustavo A. Bezerra and Karl Gruber Peptide binding and cleavage by human dipeptidylpeptidase III Publikation in PURE anzeigen

Prashant Kumar, Gustavo A. Bezerra, Elena Dobrovetsky, Roland Viertlmayr, Alexandra Binter, Marija Abramic, Peter Macheroux, Sirano Dhe-Paganon and Karl Gruber Entropy-driven binding of an opioid peptide induces a large domain motion in human DPPIII Publikation in PURE anzeigen

Bastian Daniel, Silvia Wallner, Altijana Hromic, Prashant Kumar, Karl Gruber and Peter Macheroux Structure and phylogenetics of bicovalent flavoenzymes from Arabidopsis thaliana Publikation in PURE anzeigen

Reinmar Stefan Eggers, Peter Macheroux, Tomas Werner and Maaz Anwar Bridging the Gap: Berberine Bridge Enzyme-like Proteins in Arabidopsis thaliana Publikation in PURE anzeigen

2012

Tanja Knaus, Markus Schober, Bernhard Kepplinger, Martin Mario Faccinelli, Julia Pitzer, Kurt Faber, Peter Macheroux and Ulrike Wagner Structure and mechanism of the first inverting alkylsulfatase specific for secondary alkyl sulfates Publikation in PURE anzeigen

Silvia Wallner, Altijana Hromic, Andreas Winkler, Karl Gruber and Peter Macheroux Catalytic and structural role of a conserved active site histidine in berberine bridge enzyme Publikation in PURE anzeigen

Michael Toesch, Markus Schober, Tanja Knaus, Peter Macheroux, Ulrike Wagner and Kurt Faber A two-step enantioconvergent process for the deracemisation of sec-alcohols via inverting and retaining alkylsulfatases Publikation in PURE anzeigen

Katharina Durchschein, W. Schwab, W. Hummel, Harald Gröger, Silvia Wallner, Peter Macheroux, Klaus Zangger and Kurt Faber Non-flavin ene-reductases for the reduction of activated C=C-double bonds Publikation in PURE anzeigen

Katharina Durchschein, Silvia Wallner, Peter Macheroux, Klaus Zangger, Walter Fabian and Kurt Faber Unusual C=C-bond isomerization of an alpha,beta-unsaturated gamma-butyrolactone catalyzed by flavoproteins from the Old Yellow Enzyme family Publikation in PURE anzeigen

Joanna M. Krysiak, Johannes Kreuzer, Peter Macheroux, Albin Hermetter, Stephan A. Sieber and Rolf Breinbauer Activity-Based Probes for Studying the Activity of Flavin-Dependent Oxidases and for the Protein Target Profiling of Monoamine Oxidase Inhibitors Publikation in PURE anzeigen

Katharina Durchschein, Silvia Wallner, Peter Macheroux, Wilfried Schwab, Thorsten Winkler, Wolfgang Kreis and Kurt Faber Nicotinamide-dependent ene reductases as alternative biocatalysts for the reduction of activated alkenes Publikation in PURE anzeigen

Verena Resch, Horst Lechner, Jörg H. Schrittwieser, Silvia Wallner, Karl Gruber, Peter Macheroux and Wolfgang Kroutil Inverting the regioselectivity of berberine bridge enzyme employing customized fluorine-containing substrates Publikation in PURE anzeigen

Markus Schober, Tanja Knaus, Michael Toesch, Peter Macheroux, Ulrike Wagner and Kurt Faber The substrate spectrum of the inverting sec-alkylsulfatase Pisa1 Publikation in PURE anzeigen

Tanja Knaus, Elisabeth Eger and Peter Macheroux An unusual flavin binding site in a putative protease from Bacteroides thetaiotaomicron Publikation in PURE anzeigen

Bastian Daniel, Silvia Wallner, Gustav Oberdorfer, Altijana Hromic, [No Value] Dully Corinna, Karl Gruber and Peter Macheroux Berberine bridge enzyme and the family of bicovalent flavoenzymes Publikation in PURE anzeigen

Bastian Daniel, Silvia Wallner, Altijana Hromic, Corinna Dully and Peter Macheroux Berberine bridge enzyme and the family of bicovalent flavoenzymes Publikation in PURE anzeigen

Tea Pavkov-Keller, Alexandra Binter, Georg Steinkellner, Kerstin Steiner, Peter Macheroux and Karl Gruber Enzymatic characterization of two novel enzymes with enone-reductase activity Publikation in PURE anzeigen

Tamara Wriessnegger, Peter Augustin, Anita Emmerstorfer, Monika Müller, Ivona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler (+)-Nootkatone production in yeasts Publikation in PURE anzeigen

Eva Fischereder, Jörg Schrittwieser, Verena Resch, Peter Macheroux and Wolfgang Kroutil Proposal of reaction pathway for the transformation of N-ethyl benzylisoquinolines by the berberine bridge enzyme BBE Publikation in PURE anzeigen

Venugopal Gudipati, Wolf-Dieter Lienhart, Karin Koch, Jürgen Dohmen and Peter Macheroux Yeast quinone reductase Lot6p mediates the degradation of transcription factor Yap4p by the 20S proteasome Publikation in PURE anzeigen

Tamara Wriessnegger, Peter Andreas Augustin, M. Müller, I. Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler The yeast Pichia pastors as whole cell biocatalyst for the production of terpenoid compounds Publikation in PURE anzeigen

Gustav Oberdorfer, Georg Steinkellner, Silvia Wallner, Katharina Durchschein, Peter Macheroux, Kurt Faber and Karl Gruber Stereopreferences of Old Yellow Enzymes: Structure correlations and sequence patterns in enoate reductases Publikation in PURE anzeigen

Gustav Oberdorfer, Alexandra Binter, Cristian Ginj, Peter Macheroux and Karl Gruber Structural and functional characterization of NikO, an enolpyruvyl transferase essential in nikkomycin biosynthesis Publikation in PURE anzeigen

Tanja Knaus, Elisabeth Eger, Julia Koop, Steve Stipsits, Cynthia L. Kinsland, Steven E. Ealick and Peter Macheroux Reverse structural genomics: An unusual flavin binding site in a putative protease from Bacteroides thetaiotaomicron Publikation in PURE anzeigen

Markus Schober, Michael Toesch, Tanja Knaus, Ulrike Wagner, Peter Macheroux and Kurt Faber Stereocomplementary sec-alkylsulfatases for the deracemization of sec-alcohols Publikation in PURE anzeigen

Jörg H. Schrittwieser, Bas Groenendaal, Verena Resch, Diego Ghislieri, Silvia Wallner, Eva-Maria Fischereder, Elisabeth Fuchs, Barbara Grischek, Johann H. Sattler, Peter Macheroux, Nicholas J. Turner and Wolfgang Kroutil Chemo/bi-enzymatic redox cascade for the enantioconvergent transformation of rac-benzylisoquinolines into (S)-berines Publikation in PURE anzeigen

Chaitanya Tabib, Thomas Bergner, Silvia Lang, Karl Gruber, Ellen Zechner and Peter Macheroux Mechanistic understanding of the bacterial bioluminescence Publikation in PURE anzeigen

Gustavo Arruda Bezerra, Elena Dobrovetsky, Roland Viertlmayer, Aiping Dong, Alexandra Binter, Marija Abramic, Peter Macheroux, Sirano Dhe-Paganon and Karl Gruber Entropy-driven binding of opioid peptides induces a large domain motion in human dipeptidyl peptidase III Publikation in PURE anzeigen

Joanna Maria Krysiak, Johannes Kreuzer, Peter Macheroux, Albin Hermetter, Stephan A. Sieber and Rolf Breinbauer Aktivitätsbasierte Sondenmoleküle zur Untersuchung der Aktivität Flavin-abhängiger Oxidasen und zum Zielprotein-Profiling von Monoaminooxidase-Inhibitoren Publikation in PURE anzeigen

Thomas Bergner, Tea Pavkov-Keller, Katharina Lukas, Jakob Kowaliuk, Markux Plank, Karl Gruber and Peter Macheroux Structural characterization of 2-aminobenzoyl-CoA monooxygenase/reductase from Azoarcus evansii regarding its substrate binding ability Publikation in PURE anzeigen

Nina Jajcanin-Jozic, Peter Macheroux and Maja Abramic Yeast ortholog of peptidase family M49: The role of invariant glutamic acid 461 and tyrosine 327 Publikation in PURE anzeigen

Silvia Wallner, Altijana Hromic, Barbara Steiner, Bastian Daniel, Andreas Winkler, Karl Gruber and Peter Macheroux Role of a conserved active site histidine in berberine bridge enzyme Publikation in PURE anzeigen

Tea Pavkov-Keller, Alexandra Binter, Georg Steinkellner, K. Steiner, Peter Macheroux and Karl Gruber Enzymatic characterization of two novel enzymes with enone-reductase activity Publikation in PURE anzeigen

Venugopal Gudipati, Wolf-Dieter Lienhart, Karin Koch and Peter Macheroux Yeast quinone reductase Lot6p and its interactions with 20S proteasome and Yap4p Publikation in PURE anzeigen

Bastian Daniel, Silvia Wallner, Altijana Hromic, Corinna Dully and Peter Macheroux Novel patterns of bicovalent flavinylation in flavoenzymes Publikation in PURE anzeigen

Silvia Wallner, Andreas Winkler, Sabrina Riedl, Corinna Dully, Stefanie Horvath, Karl Gruber and Peter Macheroux Catalytic and structural role of a conserved active site histidine in berberine bridge enzyme Publikation in PURE anzeigen

Verena Resch, Horst Lechner, Jörg Schrittwieser, Silvia Wallner, Katharina Gruber, Peter Macheroux and Wolfgang Kroutil Controlling the regioselectivity of the berberine bridge enzyme by reaction and substrate engineering Publikation in PURE anzeigen

Tea Pavkov-Keller, Katharina Lukas, Thomas Bergner, Peter Macheroux and Karl Gruber Towards the structural characterization of 2-aminobenzoyl-CoA monooxygenase/reductase, a flavoprotein from Azoarcus evansii Publikation in PURE anzeigen

Anita Emmerstorfer, M. Müller, I. Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler Saccharomyces cerevisiae as whole-cell biocatalyst for terpenoid production Publikation in PURE anzeigen

Peter Macheroux Technik bewegt: Mit dem TU Graz-Rad von Prag nach Berlin Publikation in PURE anzeigen

Markus Schober, Michael Toesch, Tanja Knaus, Peter Macheroux, Ulrike Wagner and Kurt Faber Stereocomplementary sec-alkylsulfatases for the deracemization of sec-alcohols Publikation in PURE anzeigen

Peter Macheroux, Tanja Knaus, Bastian Daniel, Alexandra Binter, Tea Pavkov-Keller and Karl Gruber Reverse structural flavogenomics: Discovery of function for uncharacterized flavoproteins Publikation in PURE anzeigen

Domen Zafred, Andy Nandy, Silvia Wallner, Andrea Camattari, Peter Macheroux and Walter Keller Phl p 4, an exciting allergen Publikation in PURE anzeigen

Tamara Wriessnegger, Peter Augustin, Anita Emmerstorfer, Ariane Fankl, Monika Müller, Iwona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler Pichia pastoris as whole-cell biocatalyst for (+)-nootkatone production Publikation in PURE anzeigen

Gustavo A. Bezarra, Marija Abramic, Peter Macheroux, Sirano Dhe-Paganon and Karl Gruber Substrate binding to dipeptidyl peptidase III: conformational changes and thermodynamics Publikation in PURE anzeigen

Elina Siirola, Eva-Maria Fischereder, Aashrita Rajagopalan, Katharina Cristin Tauber, Horst Lechner, Francesco Mutti, Christine Fuchs, Desiree Pressnitz, Robert Christian Simon, Jörg Schrittwieser, Verena Resch, Johann Sattler, Karl Gruber, Peter Macheroux and Wolfgang Kroutil Biocatalytic approaches to novel alkaloids Publikation in PURE anzeigen

Robert Christina Simon, Johann Sattler, Katharina Christin Tauber, Elina Siirola, Jörg Schrittwieser, Verena Resch, Eva-Maria Fischereder, Horst Lechner, Francesco Mutti, Christine Fuchs, Desiree Pressnitz, Peter Macheroux, Nick Turner and Wolfgang Kroutil Cascade reactions to access optically pure prim-, sec- and test-amines Publikation in PURE anzeigen

Markus Schober, Michael Toesch, Tanja Knaus, Ulrike Wagner, Peter Macheroux and Kurt Faber Stereocomplementary sec-alkylsulfatases for the deracemization of sec-alcohols Publikation in PURE anzeigen

Jörg H. Schrittwieser, Verena Resch, E.-M. Fischereder, Horst Lechner, D. Pressnitz, J. H. Sattler, Karl Gruber, Peter Macheroux and Wolfgang Kroutil The berberine bridge enzyme enables access to novel berbine alkaloids Publikation in PURE anzeigen

Wolf-Dieter Lienhart, Venugopal Gudipati and Peter Macheroux The role of NAD(P)H:quinone oxidoreductase 1 in human cancer development Publikation in PURE anzeigen

Bastian Daniel, Silvia Wallner, Altijana Hromic, Prashant Kumar, Karl Gruber and Peter Macheroux Expression and characterization of bicovalent flavoenzymes from Arabidopsis thaliana Publikation in PURE anzeigen

Petra Gadler, Markus Schober, Michael Toesch, Ulrike Wagner, C. Gülly, Ruth Birner-Grünberger, Tanja Knaus, Peter Macheroux and Kurt Faber Stereo- & enantio-complementary enzymes: alkyl sulfatases Publikation in PURE anzeigen

Silvia Wallner, Corinna Dully, Bastian Daniel and Peter Macheroux Berberine bridge enzyme and the family of bicovalent flavoenzymesHandbook of Flavoproteins, Volume 11-30 Publikation in PURE anzeigen

2011

Tamara Wriessnegger, Peter Augustin, Anita Emmerstorfer, Monika Müller, Iwona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler Pichia pastoris as Whole-Cell Biocatalyst for (+)-Nootkatone Production Publikation in PURE anzeigen

Katharina Durchschein, Walter M. F. Fabian, Peter Macheroux, Klaus Zangger, Gregor Trimmel and Kurt Faber Reductive biotransformation of nitroalkenes via nitroso-intermediates to oxazetes catalyzed by xenobiotic reductase (XenA) Publikation in PURE anzeigen

Thomas Bergner, Steve Stipsits, Andreas Winkler, Heidemarie Kayer, John Lee, Steve Mayhew, Franz Müller, Karl Gruber and Peter Macheroux Structure and properties of recombinant LuxF from Photobacterium leiognathi Publikation in PURE anzeigen

Alexandra Binter, Gustav Oberdorfer, Stefanie Nerstheimer, Sebastian Hofzumahaus, Georg Altenbacher, Karl Gruber and Peter Macheroux Characterisation of the PLP-dependent aminotransferase NikK from Streptomyces tendae and its putative role in nikkomycin biosynthesis Publikation in PURE anzeigen

Markus Schober, Tanja Knaus, M. Toesch, Peter Macheroux, Ulrike Wagner and Kurt Faber A stereoselective inverting sec-alkylsulfatase for the deracemisation of sec-alcohols Publikation in PURE anzeigen

Tanja Knaus, Markus Schober, Ullrike Wagner, Kurt Faber and Peter Macheroux Structural and molecular characterisation of the first inverting sec-alkylsulfatase (pisa1) from Pseudomonas sp. Publikation in PURE anzeigen

Verena Resch, Jörg Schrittwieser, Silvia Wallner, Peter Macheroux and Wolfgang Kroutil Biocatalytic oxidative C-C bond formation catalysed by berberine bridge enzyme: optimal reaction conditions Publikation in PURE anzeigen

Tanja Knaus, Elisabeth Eger, Steve Stipsits and Peter Macheroux A putative protease from Bacteroides thetaiotaomicron - the first zinc-dependent flavoprotein Publikation in PURE anzeigen

Anita Emmerstorfer, Tamara Wriessnegger, Peter Augustin, Monika Müller, Iwona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler Heterologous Expression of CYP71D55 in S. cerevisiae for (+)-Nootkatone Production Publikation in PURE anzeigen

Frank Jankowitsch, Christian Kühm, Roland Kellner, Jörn Kalinowski, Stefan Pelzer, Peter Macheroux and Matthias Mack A novel N,N-8-amino-8-demethyl-D-riboflavin dimethyltransferase (RosA) catalyzing the two terminal steps of roseoflavin biosynthesis in Streptomyces davawensis Publikation in PURE anzeigen

Jörg H Schrittwieser, Verena Resch, Silvia Wallner, Wolf-Dieter Lienhart, Johann H Sattler, Jasmin Resch, Peter Macheroux and Wolfgang Kroutil Biocatalytic organic synthesis of optically pure (S)-scoulerine and novel berbine and benzylisoquinoline alkaloids Publikation in PURE anzeigen

Silvia Wallner, Andreas Winkler, Corinna Dully, Rosemarie Trenker-El-Toukhy and Peter Macheroux Further insights into the bicovalent flavinylation of berberine bridge enzyme Publikation in PURE anzeigen

Verena Resch, Jörg Schrittwieser, Silvia Wallner, Peter Macheroux and Wolfgang Kroutil Optimisation of the reaction conditions of the carbon-carbon-bond forming berberine bridge enzyme for the use in organic chemistry Publikation in PURE anzeigen

Peter Macheroux, Barbara Kappes and Steve E. Ealick Flavogenomics - A genomic and structural view on flavin-dependent proteins Publikation in PURE anzeigen

Matthias Schittmayer, Anton Glieder, Michael Karl Uhl, Andreas Winkler, Simone Zach, Jörg Schrittwieser, Wolfgang Kroutil, Peter Macheroux, Karl Gruber, Spiros Kambourakis, J. David Rozzell and Margit Winkler Old Yellow Enzyme catalyzed dehydrogenation of saturated ketones Publikation in PURE anzeigen

Peter Macheroux, Barbara Kappes and Steven E. Ealick A genomic and structural view of flavin-dependent proteins Publikation in PURE anzeigen

Katharina Durchschein, W. M. F. Fabian, Klaus Zangger, Peter Macheroux and Kurt Faber Unusual reactions catalysed by OYEs: bio-Nef-reaction, oxazete-formation and C=C-bond isomerisation Publikation in PURE anzeigen

Andreas Gesell, Maria Luisa Diaz Chavez, Robert Kramell, Markus Piotrowski, Peter Macheroux and Toni M Kutchan Heterologous expression of two FAD-dependent oxidases with (S)-tetrahydroprotoberberine oxidase activity from Argemone mexicana and Berberis wilsoniae in insect cells Publikation in PURE anzeigen

Jörg H. Schrittwieser, Verena Resch, Johann Sattler, Wolf-Dieter Lienhart, Katharina Durchschein, Andreas Winkler, Karl Gruber, Peter Macheroux and Wolfgang Kroutil Biocatalytic enantioselective oxidative C-C coupling by aerobic C-H activation of N-CH3 to yield novel berberine alkaloid derivatives Publikation in PURE anzeigen

Markus Schober, Tanja Knaus, Michael Toesch, Petra Gadler, Ulrike Wagner, Peter Macheroux and Kurt Faber Development of an enantioconvergent process for the deracemisation of secondary alcohols with the first inverting sec-alkylsulfatase (PISA1) from Pseudomonas sp. Publikation in PURE anzeigen

Silvia Wallner, Stefanie Horvath, Sabrina Tatzl, Rosemarie Trenker-El-Toukhy and Peter Macheroux Use of a fluorescent screening system for the heterologous expression of STOX, a new bi-covalently flavinylated oxidase Publikation in PURE anzeigen

Markus Schober, Tanja Knaus, Peter Macheroux, Ullrike Wagner and Kurt Faber A stereoselective inverting sec-alkylsulfatase for the deracemisation of sec-alcohols Publikation in PURE anzeigen

Markus Schober, Tanja Knaus, Michael Tösch, Peter Macheroux, Ulrike Wagner and Kurt Faber A stereoselective inverting sec-alkylsulfatase for the deracemisation of sec-alcohols Publikation in PURE anzeigen

Chieh-Yi Shen, Silvia Wallner, Shih-Huan Peng, Tsung-Lin Li, Peter Macheroux and Shwu-Huey Liaw Novel roles of the 6-S-cysteinyl, 8alpha-N1-histidyl FAD in glycopeptide hexose oxidase Dbv29 Publikation in PURE anzeigen

Jörg H. Schrittwieser, Verena Resch, Johann Sattler, Wolf-Dieter Lienhart, Katharina Durchschein, Andreas Winkler, Karl Gruber, Peter Macheroux and Wolfgang Kroutil Biokatalytische enantioselektive oxidative C-C-Kupplung durch C-H-Aktivierung mit molekularem Sauerstoff Publikation in PURE anzeigen

Katharina Durchschein, Peter Macheroux, Silvia Wallner, A.S. Bommarius, Y. Yanto and Kurt Faber Unusual reactions catalyzed by OYEs: Bio-Nef-reaction, oxazete-formation and C=C-bond isomerisation Publikation in PURE anzeigen

Barbara Kappes, Ivo Tews, Alexandra Binter and Peter Macheroux PLP-dependent enzymes as potential drug targets for protozoan diseases Publikation in PURE anzeigen

Markus Schober, Petra Gadler, Tanja Knaus, Heidemarie Kayer, Ruth Birner-Grünberger, Christian Gülly, Peter Macheroux, Ulrike Wagner and Kurt Faber A stereoselective inverting sec-alkylsulfatase for the deracemisation of sec-alcohols Publikation in PURE anzeigen

Jörg H. Schrittwieser, Verena Resch, Johann H. Sattler, Wolf-Dieter Lienhart, E.-M. Fischereder, Silvia Wallner, Peter Macheroux and Wolfgang Kroutil Berberine bridge enzyme: from biochemical studies to preparative-scale kinetic resolution and beyond Publikation in PURE anzeigen

Wolfgang Kroutil, Francesco Mutti, C. S. Fuchs, Desiree Presnitz, R. C. Simon, Jörg Schrittwieser, Verena Resch, Johann Sattler, Eva-Maria Fischereder, Alejandro Orden and Peter Macheroux Biocatalytic approaches to achiral prim- and tert-amines Publikation in PURE anzeigen

Jörg Schrittwieser, Verena Resch, Eva-Maria Fischereder, Alejandro Orden, Silvia Wallner, Peter Macheroux and Wolfgang Kroutil Biocatalytic oxidative enantioselective C-C-formation as the key step in the chemoenzymatic synthesis of novel optically pure berbine alkaloids Publikation in PURE anzeigen

Jörg Schrittwieser, Verena Resch, Johann Sattler, Wolf-Dieter Lienhart, Andreas Winkler, Peter Macheroux and Wolfgang Kroutil Chemoenzymatic synthesis of enantiopure benzylisoquinoline and berbine alkaloids Publikation in PURE anzeigen

Gustavo A. Bezerra, Marija Abramic, Peter Macheroux, Sirano Dhe-Paganon and Karl Gruber Structure of human dipeptidyl peptidase III in complex with an opioid peptide unveils an unusual entropy-driven binding mode Publikation in PURE anzeigen

Peter Macheroux, Barbara Kappes and Steven E. Ealick A genomic and structural view on flavin-dependent proteins Publikation in PURE anzeigen

Peter Macheroux and Wolfgang Schütz Rot: Evolution Publikation in PURE anzeigen

Silvia Wallner and Peter Macheroux Effect of different modes of covalent flavinylation on the midpoint potential of flavoproteins Publikation in PURE anzeigen

Katharina Durchschein, W. M. F. Fabian, Klaus Zangger, Peter Macheroux and Kurt Faber Unusual reactions catalyzed by OYEs: Bio-Nef-reaction, oxazete-formation and C=C-bond isomerisation (Vincent Massey Award Lecture) Publikation in PURE anzeigen

Jörg H. Schrittwieser, Verena Resch, Johann Sattler, Wolf-Dieter Lienhart, Silvia Wallner, Karl Gruber, Peter Macheroux and Wolfgang Kroutil Access to novel berbine derivatives employing the berberine bridge enzyme Publikation in PURE anzeigen

Wolfgang Kroutil, Jörg Schrittwieser, Verena Resch, Johann Sattler, Birgit Seisser, Elina Siirola, Aashrita Rajagopalan and Peter Macheroux Biocatalytic C-C bond formation and C-C cleavage Publikation in PURE anzeigen

Alexandra Binter, Gustav Oberdorfer, Sebastian Hofzumahaus, Stefanie Nerstheimer, Georg Altenbacher, Karl Gruber and Peter MacHeroux Characterization of the PLP-dependent aminotransferase NikK from Streptomyces tendae and its putative role in nikkomycin biosynthesis Publikation in PURE anzeigen

2010

Alexandra Binter, Stefanie Nernstheimer, Georg Altenbacher, Gustav Oberdorfer, Karl Gruber and Peter Macheroux NikK: An aminotransferase involved in nikkomycin biosynthesis Publikation in PURE anzeigen

Silvia Wallner, Birgit Luef and Peter Macheroux STOX, a bi-covalently flavinylated oxidase with unknown function in alkaloid biosynthesis Publikation in PURE anzeigen

Silvia Wallner, Philipp Markolin, Rosemarie Trenker-El-Toukhy and Peter Macheroux Development of a screening system for the heterologous expression of STOX, a new bi-covalently flavinylated oxidoreductase Publikation in PURE anzeigen

Markus Schober, Petra Gadler, Tanja Knaus, Peter Macheroux and Kurt Faber Molecular characterisation of the first inverting sec-alkyl sulfatase (PISA1) from Pseudomonas sp. Publikation in PURE anzeigen

Katharina Durchschein, Silvia Wallner, Peter Macheroux, Klaus Zangger and Kurt Faber Enzyme-mediated transformation of a nitroalkene to an oxazete catalyzed by xenobiotic reductase A Publikation in PURE anzeigen

Silvia Wallner, Birgit Luef and Peter Macheroux STOX, a bi-covalently flavinylated oxidase with unknown function in alkaloid biosynthesis Publikation in PURE anzeigen

Gustavo A. Bezerra, Greg Wasney, Masoud Vedadi, Doug Cossar, Sirano Dhe-Paganon, Marija Abramic, Peter Macheroux and Karl Gruber Thermodynamic and structural studies of human dipeptidylpeptidase III with substrates and inhibitors Publikation in PURE anzeigen

Tanja Knaus, Petra Gadler, Markus Schober, Kurt Faber, Ulrike Wagner and Peter Macheroux PISA1 from Pseudomonas sp., the first inverting sec-alkyl sulfatase Publikation in PURE anzeigen

Katharina Durchschein, Bianca Ferreira-da Silva, Silvia Wallner, Peter Macheroux, Wolfgang Kroutil, Silvia M Glueck and Kurt Faber The flavoprotein-catalyzed reduction of aliphatic nitro-compounds represents a biocatalytic equivalent to the Nef-reaction Publikation in PURE anzeigen

Tanja Knaus, Petra Gadler, Markus Schober, M. Faccinelli, Ulrike Wagner, Peter Macheroux and Kurt Faber Site-directed mutagenesis of PISA1 reveals active site residues involved in enantio-preference Publikation in PURE anzeigen

Katharina Durchschein, Klaus Zangger, Silvia Wallner, Peter Macheroux and Klaus Faber Enzyme-mediated transformation of a nitroalkene to an oxazete catalyzed by xenobiotic reductase A Publikation in PURE anzeigen

Nina Jajcanin-Jozic, Sigrid Deller, Tea Pavkov, Peter Macheroux and Marija Abramic Identification of the reactive cysteine residues in yeast dipeptidyl peptidase III Publikation in PURE anzeigen

Peter Macheroux Email from Ithaca Publikation in PURE anzeigen

Verena Resch, Jörg Schrittwieser, Andreas Winkler, Peter Macheroux and Wolfgang Kroutil Enantioselective synthesis of natural and non natural isoquinoline alkaloids Publikation in PURE anzeigen

Tanja Knaus, Markus Schober, Kurt Faber and Peter Macheroux Active site characterisation of the first sec-alkyl sulfatase: towards the deracemisation of sec-alcohols Publikation in PURE anzeigen

Silvia Wallner and Peter Macheroux Development of a screening system for the heterologous expression of STOX - a new bi-covalently flavinylated oxidoreductase Publikation in PURE anzeigen

Contact

Univ-Prof. Dr. Peter Macheroux

Phone: (+43) (0)316 873 6451 E-Mail: peter.macherouxnoSpam@tugraz.at