IBC - Publications

2024

Quang Hieu Tran, Oliver Maximilian Eder and Andreas Winkler Dynamics-driven allosteric stimulation of diguanylate cyclase activity in a red light-regulated phytochrome Publikation in PURE anzeigen

2023

Ursula Vide, Dzenita Kasapovic, Maximilian Fuchs, Martin Paul Heimböck, Massimo Gregorio Totaro, Elfriede Zenzmaier and Andreas Winkler Illuminating the inner workings of a natural protein switch: Blue-light sensing in LOV-activated diguanylate cyclases Publikation in PURE anzeigen

2022

Cornelia Böhm, Geoffrey Gourinchas, Sophie Zweytick, Elvira Hujdur, Martina Reiter, Sara Trstenjak, Christoph Wilhelm Sensen and Andreas Winkler Characterisation of sequence–structure–function space in sensor–effector integrators of phytochrome-regulated diguanylate cyclases Publikation in PURE anzeigen

Moona Kurttila, Stefan Etzl, Jessica Rumfeldt, Heikki Takala, Nadine Galler, Andreas Winkler and Janne A Ihalainen The structural effect between the output module and chromophore-binding domain is a two-way street via the hairpin extension Publikation in PURE anzeigen

2021

Cornelia Böhm, Nikolina Todorovic, Marco Balasso, Geoffrey Gourinchas and Andreas Winkler The PHY domain dimer interface of bacteriophytochromes mediates cross-talk between photosensory modules and output domains Publikation in PURE anzeigen

Alexander Christiansen, Marie Weiel, Andreas Winkler, Alexander Schug and Jochen Reinstein The Trimeric Major Capsid Protein of Mavirus is stabilized by its Interlocked N-termini Enabling Core Flexibility for Capsid Assembly Publikation in PURE anzeigen

2020

David Buhrke, Geoffrey Gourinchas, Melanie Müller, Norbert Michael, Peter Hildebrandt and Andreas Winkler Distinct chromophore-protein environments enable asymmetric activation of a bacteriophytochrome activated diguanylate cyclase Publikation in PURE anzeigen

Emilia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Benjamin Bourgeois, Anja Högler, Daniel Waltenstorfer, Andreas Winkler, Klaus Zangger, Tobias Madl, Karl Gruber and Peter Macheroux A small molecule chaperone rescues the stability and activity of a cancer-associated variant of NAD(P)H:quinone oxidoreductase 1 in vitro Publikation in PURE anzeigen

2019

Geoffrey Gourinchas, Uršula Vide and Andreas Winkler Influence of the N-terminal segment and the PHY-tongue element on light-regulation in bacteriophytochromes Publikation in PURE anzeigen

2018

Peter Andreas Augustin, Marina Toplak, Anna Katharina Fuchs, Eva Gerstmann, Ruth Prassl and Andreas Winkler Oxidation of the FAD cofactor to the 8-formyl-derivative in human electron-transferring flavoprotein Publikation in PURE anzeigen

Stefan Etzl, Robert Lindner, Matthew D Nelson and Andreas Winkler Structure-guided design and functional characterization of an artificial red light-regulated guanylate/adenylate cyclase for optogenetic applications Publikation in PURE anzeigen

Geoffrey Gourinchas, Udo Heintz and Andreas Winkler Asymmetric activation mechanism of a homodimeric red light-regulated photoreceptor Publikation in PURE anzeigen

Marina Toplak, Gertrud Wiedemann, Jelena Ulićević, Bastian Daniel, Sebastian N W Hoernstein, Jennifer Kothe, Johannes Niederhauser, Ralf Reski, Andreas Winkler and Peter Macheroux The single berberine bridge enzyme homolog of Physcomitrella patens is a cellobiose oxidase Publikation in PURE anzeigen

2017

Geoffrey Simon Gourinchas, Stefan Etzl, Christoph Göbl, Ursula Vide, Tobias Madl and Andreas Winkler Long-Range Allosteric Signaling in Red Light-Regulated Diguanylyl Cyclases Publikation in PURE anzeigen

Robert Lindner, Elisabeth Hartmann, Miroslaw Tarnawski, Andreas Winkler, Daniel Frey, Jochen Reinstein, Anton Meinhart and Ilme Schlichting Photoactivation Mechanism of a Bacterial Light-Regulated Adenylyl Cyclase Publikation in PURE anzeigen

2016

Hui Wang, Marco Vilela, Andreas Winkler, Miroslaw Tarnawski, Ilme Schlichting, Hayretin Yumerefendi, Brian Kuhlman, Rihe Liu, Gaudenz Danuser and Klaus M Hahn LOVTRAP: an optogenetic system for photoinduced protein dissociation Publikation in PURE anzeigen

2015

Thomas Bergner, Chaitanya Tabib, Andreas Winkler, Steve Stipsits, Heidemarie Kayer, John Lee, Stephen Mayhew, Jonathan Malthouse, Franz Müller, Karl Gruber and Peter Macheroux Structural and biochemical properties of LuxF from Photobacterium leiognathi Publikation in PURE anzeigen

Robert Lindner, Udo Heintz and Andreas Winkler Applications of hydrogen deuterium exchange (HDX) for the characterization of conformational dynamics in light-activated photoreceptors Publikation in PURE anzeigen

Andreas Winkler, Thomas R.M. Barends, Anikó Udvarhelyi, Daniel Lenherr-Frey, Lukas Lomb, Andreas Menzel and Ilme Schlichting Structural Details of Light Activation of the LOV2-based Photoswitch PA-Rac1 Publikation in PURE anzeigen

Clara Brieke, Veronika Kratzig, Kristina Haslinger, Andreas Winkler and Max J. Cryle Rapid access to glycopeptide antibiotic precursor peptides coupled with cytochrome P450-mediated catalysis: towards a biomimetic synthesis of glycopeptide antibiotics Publikation in PURE anzeigen

2014

Robert Lindner, Xinghua Lou, Jochen Reinstein, Robert L. Shoeman, Fred A. Hamprecht and Andreas Winkler Hexicon 2: Automated Processing of Hydrogen-Deuterium Exchange Mass Spectrometry Data with Improved Deuteration Distribution Estimation Publikation in PURE anzeigen

Alhosna Benjdia, Korbinian Heil, Andreas Winkler, Thomas Carell and Ilme Schlichting Rescuing DNA repair activity by rewiring the H-atom transfer pathway in the radical SAM enzyme, spore photoproduct lyase Publikation in PURE anzeigen

Udo Heintz, Anton Meinhart and Andreas Winkler Multi-PAS domain-mediated protein oligomerization of PpsR from Rhodobacter sphaeroides Publikation in PURE anzeigen

Andreas Winkler, Anikó Udvarhelyi, Elisabeth Hartmann, Jochen Reinstein, Andreas Menzel, Robert L. Shoeman and Ilme Schlichting Characterization of Elements Involved in Allosteric Light Regulation of Phosphodiesterase Activity by Comparison of Different Functional BlrP1 States Publikation in PURE anzeigen

2013

Andreas Winkler, Udo Heintz, Robert Lindner, Jochen Reinstein, Robert L. Shoeman and Ilme Schlichting A ternary AppA-PpsR-DNA complex mediates light regulation of photosynthesis-related gene expression Publikation in PURE anzeigen

2012

Silvia Wallner, Andreas Winkler, Sabrina Riedl, Corinna Dully, Stefanie Horvath, Karl Gruber and Peter Macheroux Catalytic and structural role of a conserved active site histidine in berberine bridge enzyme Publikation in PURE anzeigen

2011

Jörg H. Schrittwieser, Verena Resch, Johann Sattler, Wolf-Dieter Lienhart, Katharina Durchschein, Andreas Winkler, Karl Gruber, Peter Macheroux and Wolfgang Kroutil Biocatalytic enantioselective oxidative C-C coupling by aerobic C-H activation of N-CH3 to yield novel berberine alkaloid derivatives Publikation in PURE anzeigen

Jörg H. Schrittwieser, Verena Resch, Johann Sattler, Wolf-Dieter Lienhart, Katharina Durchschein, Andreas Winkler, Karl Gruber, Peter Macheroux and Wolfgang Kroutil Biokatalytische enantioselektive oxidative C-C-Kupplung durch C-H-Aktivierung mit molekularem Sauerstoff Publikation in PURE anzeigen