Thomas Vogl, Thomas Kickenweiz, Julia Pitzer, Lukas Sturmberger, Astrid Weninger, Bradley W Biggs, Eva-Maria Köhler, Armin Baumschlager, Jasmin Elgin Fischer, Patrick Hyden, Marlies Wagner, Martina Baumann, Nicole Borth, Martina Geier, Parayil Kumaran Ajikumar and Anton Glieder
Engineered bidirectional promoters enable rapid multi-gene co-expression optimization
Nature Communications
9,
3589,
2018
DOI:
https://doi.org/10.1038/s41467-018-05915-w
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Elisa Lanfranchi, Birgit Grill, Zainab Raghoebar, Sander Van Pelt, Roger A Sheldon, Kerstin Steiner, Anton Glieder and Margit Winkler
Production of Hydroxynitrile Lyase from Davallia tyermannii (DtHNL) in Komagataella phaffii and Its Immobilization as a CLEA to Generate a Robust Biocatalyst
ChemBioChem
19,
312-316,
2018
DOI:
https://doi.org/10.1002/cbic.201700419
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Samiro Bojarra, Dennis Reichert, Marius Grote, Álvaro Gómez Baraibar, Alexander Dennig, Bernd Nidetzky, Carolin Mügge and Robert Kourist
Bio-based α,ω functionalized hydrocarbons from multi-step reaction sequences with bio- and metallo-catalysts based on the fatty acid decarboxylase OleTJE
ChemCatChem
10,
1192-1201,
2018
DOI:
https://doi.org/10.1002/cctc.201701804
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Thomas Kickenweiz, Anton Glieder and Jin Chuan Wu
Construction of a cellulose-metabolizing Komagataella phaffii (Pichia pastoris) by co-expressing glucanases and β-glucosidase
Applied Microbiology and Biotechnology
102,
1297-1306,
2018
DOI:
https://doi.org/10.1007/s00253-017-8656-z
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Sarah Waldie, Tania K Lind, Kathryn Browning, Martine Mouline, Michael Haertlein, Trevor Forsyth, Alessandra Luchini, Gernot Strohmeier, Harald Pichler, Selma Maric and Marité Cárdenas
Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine
Langmuir
34,
472-479,
2018
DOI:
https://doi.org/10.1021/acs.langmuir.7b02716
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Matthias Engleder, Melissa Horvat, Anita Emmerstorfer-Augustin, Tamara Wriessnegger, Stefanie Gabriel, Gernot Strohmeier, Hansjörg Weber, Monika Müller, Iwona Kaluzna, Daniel Mink, Martin Schürmann and Harald Pichler
Recombinant expression, purification and biochemical characterization of kievitone hydratase from Nectria haematococca
PLoS ONE
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2018
DOI:
https://doi.org/10.1371/journal.pone.0192653
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Sandy Schmidt, Mark Dörr and Uwe T. Bornscheuer Library growth and protein expressionMethods in Molecular Biology145-156
Alternative link: Link
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Martine Moulin, Gernot Strohmeier, Melanie Hirz, Katherine Thompson, Adrian Rennie, Richard A Campbell, Harald Pichler, Selma Maric, Trevor Forsyth and Michael Haertlein
Perdeuteration of cholesterol for neutron scattering applicatioins using recombinant Pichia pastoris
Chemistry and Physics of Lipids
212,
80-87,
2018
DOI:
https://doi.org/10.1016/j.chemphyslip.2018.01.006
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Robert Kourist, Anna Schweiger and Hanna Büchsenschütz Enzymatic Decarboxylation as a Tool for the Enzymatic Defunctionalization of Hydrophobic Bio-based Organic AcidsLipid Modification by Enzymes and Engineered Microbes89-118
Alternative link: Link
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Carolin Mügge and Robert Kourist Practical considerations regarding the choice of the best high-throughput assayMethods in Molecular Biology189-208
Alternative link: Link
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Holly Stolterfoht, Georg Steinkellner, Daniel Schwendenwein, Tea Pavkov-Keller, Karl Gruber and Margit Winkler
Identification of key residues for enzymatic carboxylate reduction
Frontiers in Microbiology
9,
2018
DOI:
https://doi.org/10.3389/fmicb.2018.00250
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Harald Pichler and Anita Emmerstorfer-Augustin
Modification of Membrane Lipid Compositions in single-celled organisms–from Basics to Applications
Methods
147,
50 - 65,
2018
DOI:
https://doi.org/10.1016/j.ymeth.2018.06.009
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Alessandra Luchini, Robin Delhom, Bruno Demé, Valérie Laux, Martine Mouline, Michael Haertlein, Harald Pichler, Gernot Strohmeier, Hanna Wacklin and Giovanna Fragneto
The Impact of Deuteration on Natural and Synthetic Lipids: a Neutron Diffraction Study
Colloids and Surfaces B: Biointerfaces
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126 - 133,
2018
DOI:
https://doi.org/10.1016/j.colsurfb.2018.02.009
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Melissa Horvat, Giuseppe Fiume, Holly Stolterfoht, Daniel Schwendenwein, Sandy Schmidt and Margit Winkler Small molecule Aldehydes from Carboxylic acid bioreduction
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JiaJia Dong, Elena Fernández-Fueyo, Frank Hollmann, Caroline Paul, Milja Pasic, Sandy Schmidt, Yonghua Wang, Sabry Younes and Wuyuan Zhang
Biocatalytic oxidation reactions - a Chemist's perspective
Angewandte Chemie - International Edition
57,
9238-9261,
2018
DOI:
https://doi.org/10.1002/anie.201800343
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Matthias Engleder and Harald Pichler
On the current role of hydratases in biocatalysis
Applied Microbiology and Biotechnology
102,
5841-5858,
2018
DOI:
https://doi.org/10.1007/s00253-018-9065-7
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Cyrill Grengg, Florian Mittermayr, Neven Ukrainczyk, Eddie Koenders, Guenther Koraimann, Sabine Kienesberger and Martin Dietzel MICROBIAL INDUCED ACID CORROSION FROM A FIELD PERSPECTIVE – ADVANCES IN PROCESS UNDERSTANDING AND CONSTRUCTION MATERIAL DEVELOPMENTProceedings of final conference of RILEM TC 253-MCI3-10
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Sandra Moser, Gernot A Strohmeier, Erich Leitner, Thomas J Plocek, Koenraad Vanhessche and Harald Pichler Whole-cell (+)-ambrein production in the yeast Pichia pastoris
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Margit Winkler, Daniel Schwendenwein, Robert Archer and Karl Rumbold Screening for new plant hydroxynitrile lyases
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Melissa Horvat, Julia Zabielska, Robert Kourist and Margit Winkler Fatty Alcohols: enzymatically from Free fatty Acids
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Florian Rudroff, Margit Winkler, Daniel Schwendenwein, Anna K. Ressmann, Marko D. Mihovilovic, Uwe T. Bornscheuer and Mark Dörr The ABAO assay, a new tool for Carboxylic Acid Reductase engineering
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Florian Rudroff, Margit Winkler, Marcello Entner, Daniel Schwendenwein, Anna K. Ressmann and Marko D. Mihovilovic Fragrance synthesis via a chemo- & multi enzyme cascade
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Sandra Moser, Gernot Strohmeier, Erich Leitner, Thomas J Plocek, Koenraad Vanhessche and Harald Pichler
Whole-cell (+)-ambrein production in the yeast Pichia pastoris
Metabolic Engineering Communications
7,
2018
DOI:
https://doi.org/10.1016/j.mec.2018.e00077
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Daniel Schwendenwein, Anna K. Ressmann, Marko D. Mihovilovic, Uwe T. Bornscheuer, Mark Dörr, Florian Rudroff and Margit Winkler A novel assay for the detection of carboxylic acid reductase (CAR) activity in whole cells
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Anna Katharina Migglautsch, Melissa Willim, Bettina Schweda, Anton Glieder, Rolf Breinbauer and Margit Winkler
Aliphatic hydroxylation and epoxidation of capsaicin by Cytochrome P450 CYP505X
Tetrahedron
74,
6199-6204,
2018
DOI:
https://doi.org/10.1016/j.tet.2018.08.049
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Yan Liu, Rong Gong, Xiaoqin Liu, Peichao Zhang, Qi Zhang, You-Sheng Cai, Zixin Deng, Margit Winkler, Jianguo Wu and Wenqing Chen
Discovery and characterization of the tubercidin biosynthetic pathway from Streptomyces tubercidicus NBRC 13090
Microbial Cell Factories
17,
2018
DOI:
https://doi.org/10.1186/s12934-018-0978-8
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Anna Katharina Schweiger, Junichi Enoki, Carolin Mügge and Robert Kourist Alternative Binding Mode impairs Enantioselectivity of Arylmalonate Decarboxylase
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Leen Assil Companioni, S Schmidt, Petra Heidinger, Helmut Schwab and Robert Kourist Hetero- and Autotrophically Driven Biotransformations in C.Necator
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Holly Stolterfoht, David Gradischnig and Margit Winkler Hybrid CARs (carboxylate reductases)
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Filippo Fiorentini, Anna-Maria Hatzl, S Schmidt, Simone Savino, Anton Glieder and Andrea Mattevi
The Extreme Structural Plasticity in the CYP153 Subfamily of P450s Directs Development of Designer Hydroxylases
Biochemistry
57,
6701-6714,
2018
DOI:
https://doi.org/10.1021/acs.biochem.8b01052
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Iker Irisarri, Pooja Singh, Stephan Koblmüller, Julián Torres-Dowdall, Frederico Henning, Paolo Franchini, Christoph Fischer, Alan R Lemmon, Emily Moriarty Lemmon, Gerhard G Thallinger, Christian Sturmbauer and Axel Meyer
Phylogenomics uncovers early hybridization and adaptive loci shaping the radiation of Lake Tanganyika cichlid fishes
Nature Communications
9,
2018
DOI:
https://doi.org/10.1038/s41467-018-05479-9
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Astrid Weninger, Anna Alkofer, Christian Schmid, Johannes Bitter, Antonia Volpini de Maestri, Monika Pranjic, Margit Winkler and Anton Glieder Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell
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Anna K. Ressmann, Daniel Schwendenwein, Simon Leonhartsberger, Mark Dörr, Marko D. Mihovilovic, Uwe T. Bornscheuer, Margit Winkler and Florian Rudroff Substrate independent high-throughput assay for the quantitative assessment of carboxylic acid reductase activity in living cells
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Florian Rudroff, Anna K. Ressmann, Daniel Schwendenwein, Simon Leonhartsberger, Mark Dörr, Marko D. Mihovilovic, Uwe T. Bornscheuer and Margit Winkler Synthesis of fragrance aldehydes by the combination of chemo and biocatalysis in microbial cell factories
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Sandra Moser, Gernot A. Strohmeier, Erich Leitner, Thomas J. Plocek, K. Vanhessche and Harald Pichler
Whole-cell (+)-ambrein production in the yeast Pichia pastoris
Metabolic Engineering Communications
7,
2018
DOI:
https://doi.org/10.1016/j.mec.2018.e00077
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Hanna Christiane Büchsenschütz, Fabian Schultes, S Schmidt and Robert Kourist A light-driven enzyme cascade reaction for the synthesis of lactones
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Hanna Christiane Büchsenschütz, Fabian Schultes, S Schmidt and Robert Kourist A light-driven enzyme cascade reaction for the synthesis of lactones.
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Raquel S. Correia Cordeiro, Junichi Enoki, Florian Busch, Carolin Mügge and Robert Kourist
Cloning and characterization of a new delta-specific L-leucine dioxygenase from Anabaena variabilis
Journal of Biotechnology
284,
68-74,
2018
DOI:
https://doi.org/10.1016/j.jbiotec.2018.07.038
Alternative link: Link
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Karim Aljakouch, Tatjana Lechtonen, Hesham K. Yosef, Mohamad K. Hammoud, Wissam Alsaidi, Carsten Kötting, Carolin Mügge, Robert Kourist, Samir F. El-Mashtoly and Klaus Gerwert
Raman Microspectroscopic Evidence for the Metabolism of a Tyrosine Kinase Inhibitor, Neratinib, in Cancer Cells
Angewandte Chemie - International Edition
57,
7250-7254,
2018
DOI:
https://doi.org/10.1002/anie.201803394
Alternative link: Link
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Kristin L. Leskoske, Françoise M. Roelants, Anita Emmerstorfer-Augustin, Christoph M. Augustin, Edward P. Si, Jennifer M. Hill and Jeremy Thorner
Phosphorylation by the stress-activated MAPK Slt2 down-regulates the yeast TOR complex 2
Genes and Development
32,
1576-1590,
2018
DOI:
https://doi.org/10.1101/gad.318709.118
Alternative link: Link
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Joseph Hosford, Morgane Valles, Florian W. Krainer, Anton Glieder and Lu Shin Wong
Parallelized biocatalytic scanning probe lithography for the additive fabrication of conjugated polymer structures
Nanoscale
10,
7185-7193,
2018
DOI:
https://doi.org/10.1039/c8nr01283k
Alternative link: Link
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Thorsten Bachler, Astrid Weninger, Anton Glieder and Margit Winkler Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients
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Kathrin Heckenbichler, Anna Katharina Schweiger, Karl Gruber, Peter Macheroux and Rolf Breinbauer New “old yellow enzyme”: a reductive C-C bond formation using engineered enoate reductase
Show publication in PURE
Thorsten Bachler, Astrid Weninger, Anton Glieder and Margit Winkler Cytochrome P450 CYP505 mutants for biooxidations of active pharmaceutical ingredients
Show publication in PURE
Melissa Horvat, Giuseppe Fiume, Holly Stolterfoht, Daniel Schwendenwein, Sandy Schmidt and Margit Winkler Small molecule Aldehydes from Carboxylic acid bioreduction
Show publication in PURE
Holly Stolterfoht, Daniel Schwendenwein, Florian Rudroff, Harald Pichler and Margit Winkler Identification of key residues in Neurospora crassa Carboxylate reductase (CAR)
Show publication in PURE
Birgit Grill, Tea Pavkov-Keller, Sarah Trunk, Barbara Darnhofer, Helmut Schwab, Margit Winkler, Melanie Hall and Kerstin Steiner Enzymatic alkene cleavage to Aldehydes and ketones
Show publication in PURE
H. Sprenger, S. Kienesberger, B. Pertschy, L. Pöltl, B. Konrad, P. Bhutada, D. Vorkapic, D. Atzmüller, F. Feist, C. Högenauer, G. Gorkiewicz and E.L. Zechner
Fic proteins of Campylobacter fetus subsp. venerealis form a network of functional toxin-antitoxin systems
Frontiers in Microbiology
,
2017
DOI:
https://doi.org/10.3389/fmicb.2017.01965
Alternative link: Link
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S Schmidt, Christoph K. Winkler, Hanna Christiane Büchsenschütz, Viktorija Vidimce-Risteski, Wolfgang Kroutil and Robert Kourist Photosynthesis-driven Asymmetric reduction of c=c double bonds
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S Schmidt, Wuyuan Zhang, Laura Leemans Martin, Elena Fernandez Fueyo, Milja Pesic, Rainer Wardenga, Wolfgang Kroutil and Frank Hollmann A ‘COMBINATORIAL EXPLOSION’ OF PRODUCTS THROUGH PHOTO-CHEMO-ENZYMATIC CASCADES
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Tiago Pedroso de Almeida, Sabry H.H. Younes, Elena Fernandez Fueyo, S Schmidt, Isabel W. C. E. Arends, Antonio Riul Jr. and Frank Hollmann SETUP AND CHARACTERIZATION OF A CASCADE TRANSFORMING ARYL ALCOHOLS INTO Β-NITRO-ARYL ALCOHOLS
Show publication in PURE
Christoph K. Winkler, S Schmidt, Hanna Christiane Büchsenschütz, Viktorija Vidimce-Risteski, Robert Kourist and Wolfgang Kroutil Photobiocatalytic Nicotinamide Recycling
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Daniel Schwendenwein, Florian Rudroff and Margit Winkler Cascade reactions for aldehyde generation in vivo
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Florian Rudroff, Anna K. Ressmann, Daniel Schwendenwein, Simon Leonhartsberger, Mark Dörr, Marko D. Mihovilovic, Uwe T. Bornscheuer, Margit Winkler, Michael J. Fink, Sofia Milker, Thomas Bayer, Thomas Wiesinger and Nikolin Oberleitner Catalytic Cascades – ‘En Route’ to Applied Biochemical Cell Factories
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Peter Ulz, Michael R. Speicher and Gerhard Thallinger Reconstruction of mitochondrial genotypes from diverse next generation sequencing datasetsProceedings of the 10th International joint conference on Biomedical Engineering Systems and Technologiesin press
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Jonathan Guyang Ling, Doris Huai-Xia Quay, Rozida Mohd. Khalid, Munir Abdul Murad, Margit Winkler and Farah Diba Abu Bakar S620A Mutation in Neurospora crassa Carboxylic acid Reductase abolishes Function
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Margit Winkler Plant Defense as a Biotech Tool
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Margit Winkler How to prepare flavors and fragrances by enzymes
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Rui M C Portela, Thomas Vogl, Katharina Ebner, Rui Oliveira and Anton Glieder
Pichia pastoris Alcohol Oxidase 1 (AOX1) Core Promoter Engineering by High Resolution Systematic Mutagenesis
Biotechnology Journal
,
2017
DOI:
https://doi.org/10.1002/biot.201700340
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Astrid Weninger, Jasmin Fischer, Hana Raschmanová, Claudia Kniely, Thomas Vogl and Anton Glieder
Expanding the CRISPR/Cas9 toolkit for Pichia pastoris with efficient donor integration and alternative resistance markers
Journal of Cellular Biochemistry
,
2017
DOI:
https://doi.org/10.1002/jcb.26474
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Kristína Markošová, Andrea Camattari, Michal Rosenberg, Anton Glieder, Nicholas J Turner and Martin Rebroš
Cloning and upscale production of monoamine oxidase N (MAO-N D5) by Pichia pastoris
Biotechnology Letters
,
2017
DOI:
https://doi.org/10.1007/s10529-017-2450-y
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Rui M C Portela, Thomas Vogl, Claudia Kniely, Jasmin E Fischer, Rui Oliveira and Anton Glieder
Synthetic Core Promoters as Universal Parts for Fine-Tuning Expression in Different Yeast Species
ACS Synthetic Biology
6,
471-484,
2017
DOI:
https://doi.org/10.1021/acssynbio.6b00178
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Uwe T. Bornscheuer and Robert Kourist Evolving Enzymes for BiocatalysisConsequences of Microbial Interactions with Hydrocarbons, Oils, and Lipids: Production of Fuels and Chemicals1-17
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Elisa Lanfranchi, Tea Pavkov-Keller, Eva-Maria Koehler, Matthias Diepold, Kerstin Steiner, Barbara Darnhofer, Jürgen Hartler, Tom Van Den Bergh, Henk-Jan Joosten, Mandana Gruber-Khadjawi, Gerhard G Thallinger, Ruth Birner-Gruenberger, Karl Gruber, Margit Winkler and Anton Glieder
Erratum
Scientific Reports
7,
2017
DOI:
https://doi.org/10.1038/srep46834
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Robert Kourist and Carolin Mügge Practical Considerions Regarding the Choice of High-Throughput-AssaysProtein Engineering- Methods and Protocols189-208
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Robert Kourist and Uwe T. Bornscheuer BiocatalysisApplied Homogeneous Catalysis with Organometallic Compounds
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Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer, Hromic Altijana, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Daniel Mink, Martin Schürmann, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler Application of hydratases for flavour and fragrance synthesis
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Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer, Altijana Hromic, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Mink Daniel, Martin Schürmann, Silvia Wallner, Peter Macheroux, Harald Pichler and Karl Gruber Application of hydratases for flavor and fragrance synthesis
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Sandra Moser, Tamara Wriessnegger, Anita Emmerstorfer-Augustin, Erich Leitner, Monika Müller, Iwona Kaluzna, Martin Schürmann, Mink Daniel and Harald Pichler Enhancing cytochrome P450-mediated conversions in P. pastoris
Show publication in PURE
Sandra Moser, Tamara Wriessnegger, Anita Emmerstorfer-Augustin, Miriam Wimmer-Teubenbacher, Erich Leitner, Matthias Engleder, Monika Müller, Martin Schürmann, Harald Pichler and Mink Daniel Enhancing (+)-nootkatone production in Pichia pastoris and Saccharomyces cerevisiae through cytochrome P450-mediated conversions
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Anton Glieder Chemicals made by Pichia pastoris
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Anton Glieder Heme Enzymes for Biocatalysis
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Anton Glieder Protein expression: Yeast or E. coli
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Sandra Moser, Tamara Wriessnegger, Anita Emmerstorfer-Augustin, Miriam Wimmer-Teubenbacher, Erich Leitner, Matthias Engleder, Monika Müller, Mink Daniel, Martin Schurmann and Harald Pichler Enhancing (+)-nootkatone production in P. pastoris and S. cerevisiae through CYP450-mediated conversions
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Aline Telzerow, Martin Schuermann, Helmut Schwab and Kerstin Steiner Crystal structure of a novel (R)-selective amine transaminase and approaches to broaden its substrate scope by rational engineering
Show publication in PURE
Alexander J A Deutsch, Beate Rinner, Martin Pichler, Katharina Prochazka, Katrin Pansy, Marco Bischof, Karoline Fechter, Stefan Hatzl, Julia Feichtinger, Kerstin Wenzl, Marie-Therese Frisch, Verena Stiegelbauer, Andreas Prokesch, Anne Krogsdam, Heinz Sill, Gerhard G Thallinger, Hildegard T Greinix, Chenguang Wang, Christine Beham-Schmid and Peter Neumeister
NR4A3 Suppresses Lymphomagenesis through Induction of Proapoptotic Genes
Cancer Research
77,
2375-2386,
2017
DOI:
https://doi.org/10.1158/0008-5472.CAN-16-2320
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Vicente Planells-Palop, Ali Hazazi, Julia Feichtinger, Jana Jezkova, Gerhard Thallinger, Naif O Alsiwiehri, Mikhlid Almutairi, Lee Parry, Jane A Wakeman and Ramsay J McFarlane
Human germ/stem cell-specific gene TEX19 influences cancer cell proliferation and cancer prognosis
Molecular Cancer
16,
2017
DOI:
https://doi.org/10.1186/s12943-017-0653-4
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Octavia N. Kracht, Ann-Christin Ammann, Julia Stockmann, D Wibberg, J Kalinowski, M Piotrowski, R Kerr, T. B. Brück and R. Kourist
Transcriptome Profiling of the Australian arid-land Plant Eremophila serrulata for the Identification of Monoterpene synthases
Phytochemistry
136,
15-22,
2017
DOI:
https://doi.org/10.1016/j.phytochem.2017.01.016
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Holly Stolterfoht, Daniel Schwendenwein, Christoph Wilhelm Sensen, Florian Rudroff and Margit Winkler
Four distinct types of E.C. 1.2.1.30 enzymes can catalyze the reduction of carboxylic acids to aldehydes
Journal of Biotechnology
257,
222-232,
2017
DOI:
https://doi.org/10.1016/j.jbiotec.2017.02.014
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Tea Pavkov-Keller, Kerstin Steiner, Mario Faber, Martin Tengg, Helmut Schwab, Mandana Gruber-Khadjawi and Karl Gruber
Crystal Structure and Catalytic Mechanism of CouO, a Versatile C-Methyltransferase from Streptomyces rishiriensis
PLoS ONE
12,
1-14,
2017
DOI:
https://doi.org/10.1371/journal.pone.0171056
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Elisa Lanfranchi, Tea Pavkov-Keller, Eva-Maria Koehler, Matthias Diepold, Kerstin Steiner, Barbara Darnhofer, Jürgen Hartler, Tom Van Den Bergh, Henk-Jan Joosten, Mandana Gruber-Khadjawi, Gerhard G Thallinger, Ruth Birner-Gruenberger, Karl Gruber, Margit Winkler and Anton Glieder
Enzyme discovery beyond homology
Scientific Reports
7,
2017
DOI:
https://doi.org/10.1038/srep46738
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Thomas Bayer, Thomas Wiesinger, Sofia Milker, Margit Winkler, Marko D. Mihovilovic and Florian Rudroff
In Vivo Synthesis of Polyhydroxylated Compounds from a “Hidden Reservoir” of Toxic Aldehyde Species
ChemCatChem
9,
2919-2923,
2017
DOI:
https://doi.org/10.1002/cctc.201700469
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Elisabeth Ullrich, Petra Heidinger, Christoph Wilhelm Sensen and R. Krause Circulating Nucleic Acids as Early Diagnostic Markers for Sepsis
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Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer-Augustin, Altijana Hromic, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Mink Daniel, Schürmann Martin, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica
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Petra Heidinger, Thorsten Bachler, Jung Soh, Laura Villanova, Stefan Grabuschnig and Christoph Wilhelm Sensen Circulating Nucleic Acids as Early Diagnostic Markers
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Anna Katharina Schweiger, Álvaro Gómez Baraibar, Christoph K. Winkler, Wolfgang Kroutil, Sandy Schmidt and Robert Kourist Exploring the Substrate Scope of a Phenolic Acid Decarboxylase Variant
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Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Anja Högler, Daniel Waltenstorfer, Andreas Winkler, Klaus Zangger, Nadia Dandachi, Ellen Heitzer, Benjamin Bourgeois, Tobias Madl, Rolf Breinbauer, Karl Gruber and Peter Macheroux Stabilization of a cancer associated variant of human NQO1 by the use of small-molecular chaperones
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Anna K. Ressmann, Holly Stolterfoht, Daniel Schwendenwein, Marko D. Mihovilovic, Margit Winkler and Florian Rudroff Whole Cell Substrate Screening of Carboxylic acid Reductases
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Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Anja Högler, Andreas Winkler, Klaus Zangger, Nadia Dandachi, Ellen Heitzer, Benjamin Bourgeois, Tobias Madl, Rolf Breinbauer, Karl Gruber and Peter Macheroux Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones
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Astrid Weninger, Anna Alkofer, Christian Schmid, Monika Pranjic, Margit Winkler and Anton Glieder Combinatorial optimization strategies to increase Human P450 catalytic Activity in whole cell Biotransformations
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Emilia Sofia Strandback, Wolf-Dieter Lienhart, Altijana Hromic-Jahjefendic, Anja Högler, Andreas Winkler, Klaus Zangger, Nadia Dandachi, Ellen Heitzer, Benjamin Bourgeois, Tobias Madl, Rolf Breinbauer, Karl Gruber and Peter Macheroux Rescuing the stability and activity of a cancer associated variant of human NQO1 by small molecular chaperones
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Thomas Bayer, Sofia Milker, Thomas Wiesinger, Margit Winkler, Marko D. Mihovilovic and Florian Rudroff Substrate funnelling complements flux optimization tools to maximize product titers of in vivo cascades
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Astrid Weninger, Anna Alkofer, Christian Schmid, Elisabeth Höppel, Margit Winkler and Anton Glieder Concurrent optimization strategies for high level protein production: Process, strain and expression engineering
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Thorsten Bachler, Anna Alkofer, Patrycja Gralewska, Astrid Weninger, Anton Glieder, Rolf Breinbauer and Margit Winkler Substrate specificity of CYP505X from Aspergillus fumigatus
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Daniel Schwendenwein, Holly Stolterfoht, Florian Rudroff and Margit Winkler Towards improve expression of Neurospora crassa CAR to create efficient whole cell catalysts for aldehyde preparation
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Holly Stolterfoht, Daniel Schwendenwein, Florian Rudroff, Harald Pichler and Margit Winkler Identification of key residues in Neurospora crassa Carboxylate reductase (CAR)
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Daniel Schwendenwein, Giuseppe Fiume, Harald Pichler and Margit Winkler Carboxylic Acid Reductase mediated Biotransformations
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Katrin Niegelhell, Michael Süßenbacher, Katrin Jammernegg, Thomas Ganner, Daniel Schwendenwein, Helmut Schwab, Franz Stelzer, Harald Plank and Stefan Spirk Phase Separated Bicomponent Biopolymer Thin Films - Enzymatic Patterning and Protein Interaction
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Katrin Niegelhell, Michael Süßenbacher, Katrin Jammernegg, Thomas Ganner, Daniel Schwendenwein, Helmut Schwab, Franz Stelzer, Harald Plank and Stefan Spirk Enzymatic Patterning of Phase Separated Bicomponent Biopolymer Thin Films
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Anna Katharina Schweiger, Álvaro Gómez Baraibar, Christoph K. Winkler, Wolfgang Kroutil, Sandy Schmidt and Robert Kourist Exploring the Substrate Scope of a Phenolic Acid Decarboxylase Variant
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Sandy Schmidt, Kathrin Castiglione and Robert Kourist
Overcoming the incompatibility challenge in chemo-enzymatic and multi-catalytic cascade reactions.
Chemistry - a European Journal
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2017
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Stefanie Böhmer, Katharina Köninger, Alvaro Gomez-Baraibar, Samiro Bojarra, Carolin Mügge, Sandy Schmidt, Marc Nowaczyk and Robert Kourist
Enzymatic Oxyfunctionalization Driven by Photosynthetic Water-Splitting in the Cyanobacterium Synechocystis sp. PCC 6803
Catalysts
7,
2017
DOI:
https://doi.org/10.3390/catal7080240
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Severin Wedde, Philipp Rommelmann, Christian Scherkus, Sandy Schmidt, Uwe T. Bornscheuer, Andreas Liese and Harald Gröger
An alternative approach towards poly-epsilon-caprolactone through a chemoenzymatic synthesis: combined hydrogenation, bio-oxidations and polymerization without the isolation of intermediates
Green Chemistry
19,
2017
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Sandy Schmidt, Tiago Pedroso de Almeida, Dörte Rother and Frank Hollmann
Towards environmentally acceptable synthesis of chiral alpha-hydroxy ketones via oxidase-lyase cascades
Green Chemistry
19,
2017
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Anna Reimer, Severin Wedde, Svenja Staudt, Sandy Schmidt, Diana Höffer, Werner Hummel, Udo Kragl, Uwe T. Bornscheuer and Harald Gröger
Process Development through Solvent Engineering in the Biocatalytic Synthesis of the Heterocyclic Bulk Chemical ε-Caprolactone
Journal of heterocyclic chemistry
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391-396,
2017
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https://doi.org/10.1002/jhet.2595
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Sandy Schmidt, Harald Gröger and Robert Kourist
Durch Trennen verbinden
Nachrichten aus der Chemie
65,
985-988,
2017
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https://doi.org/10.1002/nadc.20174058532
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Daniel Schwendenwein, Philippe Oberhemm, Giuseppe Fiume, Florian Rudroff, Kerstin Steiner, Kinga Rudnicka and Margit Winkler Selective preparation of Aldehydes using carboxylate reductases
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Thorsten Bachler, Jörg Patrick-Rene Eichmann, Astrid Weninger, Anton Glieder, Rolf Breinbauer and Margit Winkler Towards API Metabolite Synthesis by Fungal Cytochrome P450 variants
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Christoph K. Winkler, Markus Plank, Margit Winkler and Kurt Faber Chemo-, regio- and stereoselectivity of carboxylic acid reductases
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Florian W. Krainer, Michaela A. Gerstmann, Barbara Darnhofer, Ruth Birner-Gruenberger and Anton Glieder
Biotechnological advances towards an enhanced peroxidase production in Pichia pastoris
Journal of Biotechnology
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2016
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https://doi.org/10.1016/j.jbiotec.2016.07.012
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Astrid Weninger, Anna-Maria Hatzl, Christian Schmid, Thomas Vogl and Anton Glieder
Combinatorial optimization of CRISPR/Cas9 expression enables precision genome engineering in the methylotrophic yeast Pichia pastoris
Journal of Biotechnology
235,
139-49,
2016
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https://doi.org/10.1016/j.jbiotec.2016.03.027
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Lukas Sturmberger, Paal W Wallace, Anton Glieder and Ruth Birner-Gruenberger
Synergism of proteomics and mRNA sequencing for enzyme discovery
Journal of Biotechnology
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https://doi.org/10.1016/j.jbiotec.2015.12.015
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Florian Krainer, Barbara Darnhofer, Ruth Birner-Gruenberger and Anton Glieder
Recombinant production of a peroxidase-protein G fusion protein in Pichia pastoris
Journal of Biotechnology
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24-27,
2016
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https://doi.org/10.1016/j.jbiotec.2015.12.020
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Gerhard Thallinger Lipid Data Analyzer: Automated Identification of Lipid Structures in High-Throughput LC-MS<sup>n</sup> Data
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Julia Feichtinger, Christoph Fischer, Nicole Borth and Gerhard Thallinger Comprehensive (epi)genome characterisation of CHO cells in response to evolutionary pressures
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Gerhard Thallinger Integrative Analysis of OMICS Data
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Anita Emmerstorfer and Harald Pichler Production of aromatic plant terpenoids in recombinant baker´s yeastBiotechnology of Plant Secondary Metabolism79-89
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Katrin Niegelhell, Michael Süßenbacher, Katrin Jammernegg, Thomas Ganner, Daniel Schwendenwein, Helmut Schwab, Franz Stelzer, Harald Plank and Stefan Spirk
Enzymes as Biodevelopers for Nano- And Micropatterned Bicomponent Biopolymer Thin Films.
Biomacromolecules
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https://doi.org/10.1021/acs.biomac.6b01263
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Bettina Pucher, Tamara Tomin, Katarina Fritz and Ruth Birner-Gruenberger Aberrant gene expression in human lung cancer cells after loss of ATGL
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Emilia Sofia Strandback, Wolf-Dieter Lienhart, Christoph Köberl, Altijana Hromic, Jakob Pletz, Venugopal Gudipati, Karl Gruber, Rolf Breinbauer and Peter Macheroux Towards understanding the structural destabilization of a cancer associated variant of human NQO1
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Tea Pavkov-Keller, Gernot Strohmeier, Matthias Diepold, Wilco Peeters, Natascha Smeets, Martin Schürmann, Karl Gruber, Helmut Schwab and Kerstin Steiner
Discovery and structural characterisation of new fold type IV-transaminases exemplify the diversity of this enzyme fold
Scientific Reports
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2016
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https://doi.org/10.1038/srep38183
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Bastian Daniel, Silvia Wallner, Barbara Steiner, Gustav Oberdorfer, Prashant Kumar, Eric van der Graaff, Thomas Roitsch, Christoph W Sensen, Karl Gruber and Peter Macheroux
Structure of a Berberine Bridge Enzyme-Like Enzyme with an Active Site Specific to the Plant Family Brassicaceae
PLoS ONE
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https://doi.org/10.1371/journal.pone.0156892
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Patrick Hyden, Ariane Pietzka, Anna Lennkh, Andrea Murer, Burkhard Springer, Marion Blaschitz, Alexander Indra, Steliana Huhulescu, Franz Allerberger, Werner Ruppitsch and Christoph W Sensen
Whole genome sequence-based serogrouping of Listeria monocytogenes isolates
Journal of Biotechnology
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https://doi.org/10.1016/j.jbiotec.2016.06.005
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F Busch, N. Hülsemann, J Enoki, K Miyamoto, M Bocola and R Kourist
Semiempirical QM/MM calculations reveal a step-wise proton transfer and an unusual thiolate pocket in the mechanism of the racemizing mutant G74C of arylmalonate decarboxylase
Catalysis Science & Technology
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S L Wilson, C Li, E Ramos-Padrón, C Nesbø, J Soh, C W Sensen, G Voordouw, J Foght and L M Gieg
Oil sands tailings ponds harbour a small core prokaryotic microbiome and diverse accessory communities
Journal of Biotechnology
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Veronika Perz, Altijana Hromic, Georg Steinkellner, Tea Pavkov-Keller, Karl Gruber, Klaus Bleymaier, Sabine Zitzenbacher, Armin Zankel, Claudia Mayrhofer, Carsten Sinkel, Ulf Kueper, Katharina Schlegel, Doris Ribitsch and Georg M. Guebitz
An Esterase from Anaerobic Clostridium hathewayi Can Hydrolyze Aliphatic−Aromatic Polyesters
Environmental Science & Technology
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Elisa Lanfranchi, Eva-Maria Köhler, Matthias Diepold, Tea Pavkov-Keller, Karl Gruber, Kerstin Steiner, Anton Glieder and Margit Winkler A new family of R-selective Hydroxynitrile lyases
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Daniel Schwendenwein, Florian Rudroff, Kerstin Steiner, Philippe Oberhemm, Giuseppe Fiume and Margit Winkler Aldehyde preparation with new fungal carboxylate reductases
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Thomas Bayer, Thomas Wiesinger, Sofia Milker, Margit Winkler, Florian Rudroff and Marko D. Mihovilovic Convergent Carbon Flux via Substrate Funelling for the In Vivo Production of Reactive Aldehyde Species
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Kathrin Heckenbichler, Anna Katharina Schweiger, Alexandra Binter, Peter Macheroux, Karl Gruber and Rolf Breinbauer New “old yellow enzyme”: Reductive C-C bond formation using an engineered enoate reductase
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Marc Nowaczyk and Robert Kourist
Light-driven whole cell biotransformation with recombinant cyanobacteria
Biospektrum
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https://doi.org/10.1007/s12268-016-0754-4
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Bernd Nidetzky and Christoph W Sensen
Special Issue on acib, Dedicated to the Occasion of Prof. Dr. Helmut Schwab's 65th Birthday
Journal of Biotechnology
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Linda Lee, Ye Zhang, Brittany Ozar, Christoph W Sensen and David C Schriemer
Carnivorous Nutrition in Pitcher Plants (Nepenthes spp.) via an Unusual Complement of Endogenous Enzymes
Journal of Proteome Research
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Melanie Hirz, Corinna Odar, Carmen Leithold, Harald Pichler and Helmut Schwab Optimization of Peptide Secretion in P. pastoris
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Bastian Daniel, Peter Macheroux, Silvia Wallner, Barbara Steiner, Karl Gruber and Tea Pavkov-Keller The family of berberine bridge enzyme-like proteins from <i>Arabidopsis thaliana</i>
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Melanie Hirz, Gerald Richter, Tamara Wriessnegger, Günther Zellnig, Erich Leitner and Harald Pichler Sterol-modified P. pastoris: Membrane Protein Expression and Cell Physiology
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Bastian Daniel, Barbara Steiner, Tea Pavkov-Keller, Karl Gruber, Eric van der Graaff, Thomas Roitsch, Silvia Wallner and Peter Macheroux Berberine bridge enzyme-like proteins: a multi-gene family from vascular plants
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Margit Winkler and Christoph K. Winkler
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Monatshefte für Chemie - Chemical Monthly
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https://doi.org/10.1007/s00706-016-1676-z
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Sandra Moser, Tamara Wriessnegger, Anita Emmerstorfer, Erich Leitner, Monika Müller, Iwona Kaluzna, Martin Schurmann, Mink Daniel and Harald Pichler Enhancing cytochrome P450-mediated conversions in P. pastoris
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Christoph Wilhelm Sensen CNA-based Markers for the detection of chronic diseases
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Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer-Augustin, Hromic Altijana, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Mink Daniel, Martin Schurmann, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler Structure-based reaction mechanism of oleate hydratase from Elizabethkingia meningoseptica
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Martial Rey, Menglin Yang, Linda Lee, Ye Zhang, Joey G Sheff, Christoph W Sensen, Hynek Mrazek, Petr Halada, Petr Man, Justin L McCarville, Elena F Verdu and David C Schriemer
Addressing proteolytic efficiency in enzymatic degradation therapy for celiac disease
Scientific Reports
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Anita Emmerstorfer-Augustin, Corinna Odar, Tamara Wriessnegger and Harald Pichler Metabolic engineering of Pichia pastoris for ginsenoside production
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Katrin Weinhandl, Melanie Ballach, Margit Winkler, Ahmad Mudassar, Anton Glieder, Ruth Birner-Gruenberger, Ian Fotheringham and Franck Escalettes
Pichia pastoris mutants as host strains for efficient secretion of recombinant Branched Chain Aminotransferase (BCAT)
Journal of Biotechnology
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Harald Pichler Sterol and terpenoid engineering in yeasts
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Bastian Daniel, Sabine Pils, Barbara Steiner, Silvia Wallner, Tea Pavkov-Keller, Karl Gruber, Jörg Schrittwieser, Michael Fuchs, Wolfgang Kroutil and Peter Macheroux Berberine bridge enzyme-like proteins: From characterization to application
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Daniel Schwendenwein, Giuseppe Fiume, Hansjörg Weber, Florian Rudroff and Margit Winkler
Selective Enzymatic Transformation to Aldehydes in vivo by Fungal Carboxylate Reductase from Neurospora crassa
Advanced Synthesis & Catalysis
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Christoph K. Winkler, Markus Plank, Margit Winkler and Kurt Faber Chemo-, regio- and stereoselectivity of carboxylic acid reductases
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Patrick Hyden, Ariane Pietzka, Franz Allerberger, Burkhard Springer, Christoph Sensen and Werner Ruppitsch
Draft Genome Sequence of a 94-Year-Old Listeria monocytogenes Isolate, SLCC208
Genome Announcements
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https://doi.org/10.1128/genomeA.01572-15
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Daniel Schwendenwein, Florian Rudroff and Margit Winkler Tuning the expression of Neurospora crassa carboxylic acid reductase towards an efficient whole cell catalyst for aldehyde preparation
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Zalina Magomedova, Andreea Grecu, Christoph W Sensen, Helmut Schwab and Petra Heidinger
Characterization of two novel alcohol short-chain dehydrogenases/reductases from Ralstonia eutropha H16 capable of stereoselective conversion of bulky substrates
Journal of Biotechnology
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Giuseppe Fiume, Philippe Oberhemm, Daniel Schwendenwein and Margit Winkler A new fungal carboxylic acid reductase for the preparation of aldehydes from acids
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Eduardo Busto, Michaela Gerstmann, Felix Tobola, Edmund Dittmann, Birgit Wiltschi and Wolfgang Kroutil
Systems biocatalysis: para-alkenylation of unprotected phenols
Catalysis Science & Technology
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https://doi.org/10.1039/c6cy01947a
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Tamara Wriessnegger, Sandra Moser, Anita Emmerstorfer-Augustin, Erich Leitner, Monika Müller, Iwona Kaluzna, Martin Schürmann, Mink Daniel and Harald Pichler
Enhancing cytochrome P450-mediated conversions in P. pastoris through RAD52 over-expression and optimizing the cultivation conditions
Fungal genetics and biology
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Thorsten Bachler, Jörg Patrick-Rene Eichmann, Astrid Weninger, Kerstin Hammer, Sanja Tunjic, Anton Glieder, Rolf Breinbauer and Margit Winkler Expression of fungal cytochrome P450 variants in E. coli and their validation for API metabolite synthesis
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Aline Telzerow, Maria Hakansson, Martin Schurmann, Helmut Schwab and Kerstin Steiner Identification and Characterization of 5 new (R)-selective w-Transaminases
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Myria Bekerle-Bogner, Mandana Gruber-Khadjawi, Helmar Wiltsche, Romana Wiedner, Helmut Schwab and Kerstin Steiner
(R)-Selective Nitroaldol Reaction Catalyzed by Metal-Dependent Bacterial Hydroxynitrile Lyases
ChemCatChem
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2214-2216,
2016
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https://doi.org/10.1002/cctc.201600150
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Astrid Weninger, Anna Alkofer, Raphaela Wimmer, Elisabeth Höppel, Jörg Patrick-Rene Eichmann, Christian Schmid, Margit Winkler and Anton Glieder Concurrent optimization strategies for high level protein production: Protein, strain and expression engineering
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Anton Glieder, Elisa Lanfranchi, Margit Winkler, Karl Gruber and Tea Pavkov-Keller Access and use of fern hydroxynitrile lyase for biocatalysis
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Christoph Wilhelm Sensen Creating gene models for high-value enzymes from plants and fungi
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Harald Pichler Oleate hydratase - structure function relationships and applicationPower of microbes in industry and environment33
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Harald Pichler Oleate hydratases - structure function relationship and application
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Ryan C Smith, Jonas G King, Dingyin Tao, Oana A Zeleznik, Clara Brando, Gerhard G Thallinger and Rhoel R Dinglasan
Molecular profiling of phagocytic immune cells in Anopheles gambiae reveals integral roles for hemocytes in mosquito innate immunity
Molecular & Cellular Proteomics
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https://doi.org/10.1074/mcp.M116.060723
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Peter Ulz, Gerhard G Thallinger, Martina Auer, Ricarda Graf, Karl Kashofer, Stephan W Jahn, Luca Abete, Gunda Pristauz, Edgar Petru, Jochen B Geigl, Ellen Heitzer and Michael R Speicher
Inferring expressed genes by whole-genome sequencing of plasma DNA
Nature Genetics
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Minoska Valli, Nadine E Tatto, Armin Peymann, Clemens Gruber, Nils Landes, Heinz Ekker, Gerhard G Thallinger, Diethard Mattanovich, Brigitte Gasser and Alexandra B Graf
Curation of the genome annotation of Pichia pastoris (Komagataella phaffii) CBS7435 from gene level to protein function
FEMS Yeast Research
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https://doi.org/10.1093/femsyr/fow051
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Marcia Ferreira Antunes, Fabian K. Eggimann, Matthias Kittelmann, Stephan Lütz, Steven P. Hanlon, Beat Wirz, Thorsten Bachler and Margit Winkler
Human xanthine oxidase recombinant in E. coli: A whole cell catalyst for preparative drug metabolite synthesis
Journal of Biotechnology
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Robert Krause, Bettina Halwachs, Gerhard Thallinger, Ingeborg Klymiuk, Gregor Gorkiewicz, Martin Hoenigl, Jürgen Prattes, Thomas Valentin, Katharina Heidrich, Walter Buzina, Helmut J F Salzer, Jasmin Rabensteiner, Florian Prüller, Reinhard B Raggam, Andreas Meinitzer, Christine Moissl-Eichinger, Christoph Högenauer, Franz Quehenberger, Karl Kashofer and Ines Zollner-Schwetz
Characterisation of Candida within the Mycobiome/Microbiome of the Lower Respiratory Tract of ICU Patients
PLoS ONE
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https://doi.org/10.1371/journal.pone.0155033
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Karin Koch, Altijana Hromic, Marija Sorokina, Manuel Reisinger, Karl Gruber and Peter Macheroux The flavodoxin-like proteins Pst2 and Ycp4 from Saccharomyces cerevisiae belong to the FMN-dependent NAD(P)H:quinone oxidoreductases
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Natalia Gomez-Escobar, Nasser Almobadel, Othman Alzahrani, Julia Feichtinger, Vicente Planells-Palop, Zafer Alshehri, Gerhard G Thallinger, Jane A Wakeman and Ramsay J McFarlane
Translin and Trax differentially regulate telomere-associated transcript homeostasis
Oncotarget
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https://doi.org/10.18632/oncotarget.9278
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Anita Emmerstorfer, Sandra Moser and Harald Pichler
Screening for improved isoprenoid biosynthesis in microorganisms
Journal of Biotechnology
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https://doi.org/10.1016/j.jbiotec.2016.03.051
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Julia Feichtinger, Inmaculada Hernández, Christoph Fischer, Michael Hanscho, Norbert Auer, Matthias Hackl, Vaibhav Jadhav, Martina Baumann, Peter M Krempl, Christian Schmidl, Matthias Farlik, Michael Schuster, Angelika Merkel, Andreas Sommer, Simon Heath, Daniel Rico, Christoph Bock, Gerhard G Thallinger and Nicole Borth
Comprehensive genome and epigenome characterization of CHO cells in response to evolutionary pressures and over time
Biotechnology and Bioengineering
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Chen Meng, Oana Alina Zeleznik, Gerhard G Thallinger, Bernhard Küster, Amin M Gholami and Aedín C Culhane
Dimension reduction techniques for the integrative analysis of multi-omics data
Briefings in Bioinformatics
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Thomas Vogl, Lukas Sturmberger, Thomas Kickenweiz, Richard Wasmayer, Christian Schmid, Anna-Maria Hatzl, Michaela Agnes Gerstmann, Julia Pitzer, Marlies Wagner, Gerhard G Thallinger, Martina Geier and Anton Glieder
A Toolbox of Diverse Promoters Related to Methanol Utilization
ACS Synthetic Biology
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Martin Tengg, Harald Stecher, Lisa Offner, Katharina Plasch, Felix Anderl, Hansjörg Weber, Helmut Schwab and Mandana Gruber
Methyltransferases
ChemCatChem
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2016
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Elisa Lanfranchi, Tea Pavkov-Keller, Kerstin Steiner, Karl Gruber, Margit Winkler and Anton Glieder Scent of bitter almond and a pinch of –omics: discovering a novel hydroxynitrile lyase
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Christian Scherkus, Sandy Schmidt, Uwe T. Bornscheuer, Harald Gröger, Selin Kara and Andreas Liese
A Fed-Batch Synthetic Strategy for a Three-Step Enzymatic Synthesis of Poly-ϵ-caprolactone
ChemCatChem
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Katrin Niegelhell, Michael Süßenbacher, Katrin Jammernegg, Thomas Ganner, Daniel Schwendenwein, Helmut Schwab, Harald Plank and Stefan Spirk Enzymatic Treatment for Patterning of Bicomponent Biopolymer Thin Films
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Patrick Hyden, C. Grim, Ariane Tatjana Pietzka, Marion Blaschitz, Alexander Indra, Christoph Wilhelm Sensen, Franz Allerberger, Thomas Rattei and Werner Ruppitsch Comparison of SNP based and cgMLST based typing of Listeria monocytogenes isolates from Seeliger's historical "Special Culture Collection".
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Ariane Tatjana Pietzka, Patrick Hyden, Andrea Murer, Anna Lennkh, Franz Allerberger, Burkhard Springer, Christoph Wilhelm Sensen and Werner Ruppitsch Comparison of PFGE and NGS based typing of Listeria monocytogenes isolates
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Ariane Tatjana Pietzka, Patrick Hyden, Andrea Murer, Anna Lennkh, Franz Allerberger, Burkhard Springer, Christoph Wilhelm Sensen and Werner Ruppitsch Typing of Listeria monocytogenes - PFGE versus Whole Genome Sequencing
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Patrick Hyden, C. Grim, Marion Blaschitz, Alexander Indra, Christoph Wilhelm Sensen, Franz Allerberger, Thomas Rattei and Werner Ruppitsch Comparison of SNP based and cgMLST based typing of Listeria monocytogenes isolates from Seeliger's historical "Special Listeria Culture Collection"
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Margit Winkler Selective preparation of Aldehydes using carboxylate reductases
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Filippo Fiorentini, Martina Geier, Claudia Binda, Margit Winkler, Kurt Faber, Mélanie Hall and Andrea Matteiv
Biocatalytic Characterization of Human FMO5: Unearthing Baeyer-Villiger Reactions in Humans
ACS Chemical Biology
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Elisa Lanfranchi, Köhler Eva-Maria, Matthias Diepold, Tea Pavkov-Keller, Karl Gruber, Kerstin Steiner, Anton Glieder and Margit Winkler A new family of R-selective Hydroxynitrile lyases
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Elisa Lanfranchi, Margit Winkler, Tea Pavkov-Keller, Eva-Maria Köhler, Matthias Diepold, Barbara Darnhofer, Kerstin Steiner, Gerhard Thallinger, Ruth Birner-Grünberger, Sander van Pelt, Karl Gruber and Anton Glieder The unique hydroxynitrile lyase from fern
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Romana Wiedner, Bettina Kothbauer, Tea Pavkov-Keller, Mandana Gruber, Karl Gruber, Helmut Schwab and Kerstin Steiner
Improving the Properties of Bacterial R-selective Hydroxynitrile Lyases for Industrial Applications
ChemCatChem
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Katharina Schmoelzer, Tibor Czabany, Christiane Luley, Tea Pavkov-Keller, Doris Ribitsch, Helmut Schwab, Karl Gruber, Hansjörg Weber and Bernd Nidetzky
Complete switch from α-2,3- to α-2,6-regioselectivity in Pasteurella dagmatis β-D-galactoside sialyltransferase by active-site redesign
Chemical Communications
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Elisa Lanfranchi, Eva-Maria Köhler, Barbara Darnhofer, Kerstin Steiner, Ruth Birner-Grünberger, Anton Glieder and Margit Winkler
Bioprospecting for Hydroxynitrile Lyases by Blue Native PAGE Coupled HCN Detection
Current biotechnology
4,
111-117,
2015
DOI:
https://doi.org/10.2174/2211550104666150506225048
Alternative link: Link
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Martina Geier, Christoph Brandner, Gernot A Strohmeier, Mélanie Hall, Franz Stefan Hartner and Anton Glieder
Engineering Pichia pastoris for improved NADH regeneration
Beilstein Journal of Organic Chemistry
11,
1741-8,
2015
DOI:
https://doi.org/10.3762/bjoc.11.190
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Astrid Weninger, Anton Glieder and Thomas Vogl
A toolbox of endogenous and heterologous nuclear localization sequences for the methylotrophic yeast Pichia pastoris
FEMS Yeast Research
15,
2015
DOI:
https://doi.org/10.1093/femsyr/fov082
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Magali Tanghe, Barbara Danneels, Andrea Camattari, Anton Glieder, Isabel Vandenberghe, Bart Devreese, Ingeborg Stals and Tom Desmet
Recombinant Expression of Trichoderma reesei Cel61A in Pichia pastoris
Molecular Biotechnology
57,
1010-7,
2015
DOI:
https://doi.org/10.1007/s12033-015-9887-9
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Jürgen Hartler, Alexander Triebl, Martin Trötzmüller, Andreas Ziegl, Gerald Rechberger, Friedrich Spener, Harald Köfeler and Gerhard Thallinger Lipid Data Analyzer (LDA) 2: Flexible and Automatic Identification of Lipid Structures in High-Throughput LC-MSn Data from Various Instruments
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Elisa Lanfranchi, Kerstin Steiner, Barbara Darnhofer, Ruth Birner-Grünberger, Margit Winkler and Anton Glieder Non-homologous enzyme discovery: the hydroxynitrile lyases case
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Kerstin Steiner, Anton Glieder and Mandana Gruber Cyanohydrin Formation / Henry ReactionSience of Synthesis1-5
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Petra Köfinger, Steffen Gruber and Helmut Schwab
Versatile plasmid-based expression systems for Gram-negative bacteria-General essentials exemplified with the bacterium Ralstonia eutropha H16.
New Biotechnology
32,
552-558,
2015
DOI:
https://doi.org/10.1016/j.nbt.2015.03.015
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Günther Daum, Claudia Schmidt, Martina Zandl, Lisa Klug, Isabella Klein, Martina Korber and Karin Athenstaedt The regulatory network of yeast triacylglycerol lipases
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Man-Ling Wong, Dongshan An, Sean Caffrey, Jung Soh, Xiaoli Dong, Christoph Wilhelm Sensen, Thomas Oldenburg, Stephen R. Larter and Gerrit Voordouw
Roles of Thermophiles and Fungi in Bitumen Degradation in Mostly Cold Oil Sands Outcrops
Applied and Environmental Microbiology
81,
6825-6838 ,
2015
DOI:
https://doi.org/10.1128/AEM.02221-15
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Jürgen Hartler LipidHomeEncyclopedia of Lipidomics1-3
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B. Tan, Jane Fowler, N.A. Laban, Xiaoli Dong, Christoph Wilhelm Sensen, Julia Foght and Lisa M. Gieg
Comparative analysis of metagenomes from three methanogenic hydrocarbon-degrading enrichment cultures with 41 environmental samples.
The ISME Journal
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1-18,
2015
DOI:
https://doi.org/10.1038/ismej.2015.22
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Katharina Dokulil, Tea Pavkov-Keller, Karl Gruber and Margit Winkler 7-Cyano-7-deazaguanine synthase: a reverse Nitrilase?
Show publication in PURE
Elisa Lanfranchi, Margit Winkler, Tea Pavkov-Keller, Eva-Maria Köhler, Matthias Diepold, Barbara Darnhofer, Kerstin Steiner, Gerhard Thallinger, Ruth Birner-Grünberger, Sander Van Pelt, Karl Gruber and Anton Glieder Hydroxynitrile lyase from fern: A Unique Biocatalyst
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Jürgen Hartler MassBankEncyclopedia of Lipidomics1-3
Alternative link: Link
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Tamara Wriessnegger, Anita Emmerstorfer, Sandra Moser, Miriam Wimmer-Teubenbacher, Peter Andreas Augustin, Matthias Engleder, Erich Leitner, Günther Zellnig, Monika Müller, Iwona Kaluzna, Daniel Mink, Martin Schürmann, Helmut Schwab and Harald Pichler APPLYING CYTOCHROME P450 ENZYMES FOR FLAVOUR&FRAGRANCE BIOSYNTHESIS IN YEASTS
Alternative link: Link
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Mario Faber, Tea Pavkov-Keller, Kerstin Steiner, Martin Tengg, Helmut Schwab, Karl Gruber and Mandana Gruber Elucidation of the structure and mechanism of CouO, a small molecule C-Methyltransferase from streptomyces rishiriensis
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Corinna Odar, Margit Winkler and Birgit Wiltschi
Fluoro amino acids: A rarity in nature, yet a prospect for protein engineering
Biotechnology Journal
10,
427-446,
2015
DOI:
https://doi.org/10.1002/biot.201400587
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Jürgen Hartler LIPID MAPS: Tools and DatabasesEncyclopedia of Lipidomics
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Katharina Schmoelzer, Tibor Czabany, Christiane Luley, Tea Pavkov-Keller, Doris Ribitsch, Helmut Schwab, Karl Gruber, Hansjörg Weber and Bernd Nidetzky Complete switch from alpha2,3- to alpha2,6-regioselectivity in Pasteurella dagmatis beta-D-galactoside sialyltransferase by active-site redesign
Alternative link: Link
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Ivan Hajnal, Kurt Faber, Helmut Schwab, Melanie Hall and Kerstin Steiner
Oxidative Alkene Cleavage Catalysed by Manganese-Dependent Cupin TM1459 from Thermotoga maritima
Advanced Synthesis & Catalysis
357,
3309-3316,
2015
DOI:
https://doi.org/10.1002/adsc.201500608
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Katharina Schmoelzer, Tibor Czabany, Christiane Luley, Tea Pavkov-Keller, Doris Ribitsch, Helmut Schwab, Karl Gruber, Hansjörg Weber and Bernd Nidetzky Complete switch from alpha2,3- to alpha2,6-regioselectivity in Pasteurella dagmatis beta-D-galactoside sialyltransferase by active-site redesign
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Anita Emmerstorfer, Miriam Wimmer-Teubenbacher, Tamara Wriessnegger, Erich Leitner, Monika Müller, Iwona Kaluzna, Martin Schürmann, Daniel Mink, Günther Zellnig, Helmut Schwab and Harald Pichler
Over-expression of ICE2 stabilizes cytochrome P450 reductase levels in Saccharomyces cerevisiae and Pichia pastoris
Biotechnology Journal
10,
623-635,
2015
DOI:
https://doi.org/10.1002/biot.201400780
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Ryan A. Groves, Jillian M. Hagel, Ye Zhang, Kilpatrick Korey, Levy Asaf, Marsolais Frederic, Lewinsohn Efraim, Christoph Wilhelm Sensen and Peter J. Facchini
Transcriptome Profiling of Khat (Catha edulis) and Ephedra sinica Reveals Gene Candidates Potentially Involved in Amphetamine-Type Alkaloid Biosynthesis.
PLoS ONE
10,
1-21,
2015
DOI:
https://doi.org/doi: 10.1371/journal.pone.0119701
Alternative link: Link
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Julia Pitzer, Bob Van Hove, Aaron M. Love, Parayil Kumaran Ajikumar, Marjan De Mey and Anton Glieder Novel DNA and RNA elementsSynthetic Biology65-99
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Bettina Halwachs, Gerhard Thallinger, Christoph Högenauer and Gregor Gorkiewicz Deriving patterns of gastrointestinal dysbiosis
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Jakov Ivkovic, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and Synthesis of Inhibitors of DPP3
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Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer, Altijana Hromic, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Daniel Mink, Martin Schürmann, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler ON THE REACTION MECHANISM OF THE ELIZABETHKINGIA MENINGOSEPTICA OLEATE HYDRATASE
Alternative link: Link
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Bastian Daniel, Barbara Steiner, Tea Pavkov-Keller, Andela Dordic, Alexander Gutmann, Bernd Nidetzky, Christoph Wilhelm Sensen, Eric van der Graaff, Silvia Wallner, Karl Gruber and Peter Macheroux The berberine bridge enzyme-like superfamily: A multi gene family involved in lignification, drought and pathogen response
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Tibor Czabany, Katharina Schmoelzer, Christiane Luley, Doris Ribitsch, Helmut Schwab and Bernd Nidetzky Expression of human sialyltransferase in yeast
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Florian Krainer, Simona Capone, Martin Jäger, Thomas Vogl, Michaela Agnes Gerstmann, Anton Glieder, Christoph Herwig and Oliver Spadiut
Optimizing cofactor availability for the production of recombinant heme peroxidase in Pichia pastoris.
Microbial Cell Factories
14,
1-9,
2015
DOI:
https://doi.org/10.1186/s12934-014-0187-z
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Matthias Engleder, Tea Pavkov-Keller, Anita Emmerstorfer, Hromic Altijana, Sabine Schrempf, Georg Steinkellner, Tamara Wriessnegger, Erich Leitner, Gernot Strohmeier, Iwona Kaluzna, Mink Daniel, Schürmann Martin, Silvia Wallner, Peter Macheroux, Karl Gruber and Harald Pichler
Structure-based mechanism of oleate hydratase from Elizabethkingia meningoseptica
ChemBioChem
16,
1730-1734,
2015
DOI:
https://doi.org/10.1002/cbic.201500269
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Peter Andreas Augustin, Eva Gerstmann, Altijana Hromic, Karl Gruber and Peter Macheroux Biochemical investigations on the human dimethylglycine dehydrogenase
Alternative link: Link
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Kathrin Heckenbichler, Alexandra Binter, Tea Pavkov-Keller, Georg Steinkellner, Kerstin Steiner, Karl Gruber and Peter Macheroux Identification and characterization of Tth-X and Pho-Y, novel members of the OYE family
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M. Bartsch, S.K. Gaßmeyer, K. Igarashi, M. Miyamoto, M. Rögner, M. Nowaczyc and R. Kourist
Expression of enantioselective enzymes in cyanobacteria
Microbial Cell Factories
14,
53,
2015
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Robert Kourist
A New Class of Enzymes Discovered: A Non-Heme Oxidase Produces Medium-Chain 1-Alkenes
Angewandte Chemie - International Edition
54,
4156-8,
2015
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https://doi.org/10.1002/anie.201500466
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Bastian Daniel, Tea Pavkov-Keller, Barbara Steiner, Andela Dordic, Alexander Gutmann, Bernd Nidetzky, Christoph Wilhelm Sensen, Eric van der Graaff, Silvia Wallner, Karl Gruber and Peter Macheroux Structural and biochemical characterization of a monolignol oxidoreductase from A. thaliana implies a link between the berberine bridge enzyme-like family and cell wall metabolism
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Thorsten Masuch, Anna Kusnezowa, Sebastian Nilewski, José T Bautista, Robert Kourist and Lars I Leichert
A combined bioinformatics and functional metagenomics approach to discovering lipolytic biocatalysts
Frontiers in Microbiology
6,
2015
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Ioannis Zachos, Sarah Katharina Gaßmeyer, Daniel Bauer, Volker Sieber, Frank Hollmann and Robert Kourist
Photobiocatalytic decarboxylation for olefin synthesis
Chemical Communications
51,
1918-1921,
2015
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Armin Erlacher, Tomislav Cernava, Massimiliano Cardinale, Jung Soh, Christoph Wilhelm Sensen, Martin Grube and Gabriele Berg
Rhizobiales as functional and endosymbiontic members in the lichen symbiosis of Lobaria pulmonaria L.
Frontiers in Microbiology
6,
2015
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https://doi.org/10.3389/fmicb.2015.00053
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Shosuke Yoshida, Junichi Enoki, Robert Kourist and Kenji Miyamoto
Engineered hydrophobic pocket of (S)-selective arylmalonate decarboxylase variant by simultaneous saturation mutagenesis to improve catalytic performance
Bioscience, Biotechnology and Biochemistry
79,
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2015
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https://doi.org/10.1080/09168451.2015.1060844
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MA Pribasnig, I Mrak, GF Grabner, U Taschler, O Knittelfelder, B Scherz, T. Eichmann, C Heier, L Grumet, J Kowaliuk, M Romauch, S Holler, F Anderl and R Zimmermann
α/β Hydrolase Domain-Containing 6 (ABHD6) Degrades the Late Endosomal/Lysosomal Lipid Bis(monoacylglycero)phosphate
The Journal of Biological Chemistry
290,
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2015
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https://doi.org/10.1074/jbc.M115.669168
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Margit Winkler, Thorsten Bachler, Martina Geier, Steven P Hanlon, Fabian K. Eggimann, Diogo Rodrigues, Marcia Ferreira Antunes, Matthias Kittelmann, Anton Glieder, Beat Wirz and Stephan Lütz Biotransformations for drug metabolite synthesis
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Margit Winkler, Thorsten Bachler, Martina Geier, Anton Glieder, Steven P Hanlon, Fabian K. Eggimann, Diogo Rodrigues, Marcia Antunes, Matthias Kittelmann, Beat Wirz and Stephan Lütz Drug Metabolizing Enzymes: From Heterologous Expression to Drug Metabolite Synthesis
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Atsuko Ikeda, Tetsuya Muneoka, Suguru Murakami, Ayaka Hirota, Yukari Yabuki, Takefumi Karashima, Kota Nakazono, Masahiro Tsuruno, Harald Pichler, Katsuhiko Shirahige, Yukiko Kodama, Toshi Shimamoto, Keiko Mizuta and Kouichi Funato
Sphingolipids regulate telomere clustering by affecting transcriptional levels of genes involved in telomere homeostasis
Journal of Cell Science
128,
2454-2467,
2015
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https://doi.org/10.1242/jcs.164160
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Margit Winkler Enzyme catalyzed reduction of carboxylic acids
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Bastian Daniel, Tea Pavkov-Keller, Barbara Steiner, Angela Dodic, Alexander Gutmann, Bernd Nidetzky, Christoph Wilhelm Sensen, Eric van der Graaff, Silvia Wallner, Karl Gruber and Peter Macheroux
Oxidation of monolignols by members of the berberine bridge enzyme family suggests a role in plant cell wall metabolism
The Journal of Biological Chemistry
290,
18770-18781,
2015
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Thomas Eichmann, Lukas Grumet, Ulrike Taschler, Jürgen Hartler, Christoph Heier, Aaron Woblistin, Laura Pajed, Manfred Kollroser, Gerald Rechberger, Gerhard G. Thallinger, Rudolf Zechner, Guenter Haemmerle, Robert Zimmermann and Achim Lass
ATGL and CGI-58 are lipid droplet proteins of the hepatic stellate cell line HSC-T6
Journal of Lipid Research
56,
1972-1984,
2015
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https://doi.org/10.1194/jlr.M062372
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Stefan Radl, Florian Krainer, Thomas Puffitsch and Christoph Kloss Biot Number Effects on the Local Heat and Mass Transfer Rate in Fixed and Fluidized Beds
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Thomas Vogl, Mudassar Ahmad, Florian Krainer, Helmut Schwab and Anton Glieder
Restriction site free cloning (RSFC) plasmid family for seamless, sequence independent cloning in Pichia pastoris
Microbial Cell Factories
14,
1-15,
2015
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https://doi.org/10.1186/s12934-015-0293-6
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Martina Geier, Thorsten Bachler, Steven P Hanlon, Fabian K Eggimann, Matthias Kittelmann, Hansjörg Weber, Stephan Lütz, Beat Wirz and Margit Winkler
Human FMO2-based microbial whole-cell catalysts for drug metabolite synthesis
Microbial Cell Factories
14,
1-10,
2015
DOI:
https://doi.org/10.1186/s12934-015-0262-0
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Florian Krainer and Anton Glieder
An updated view on horseradish peroxidases: recombinant production and biotechnological applications.
Applied Microbiology and Biotechnology
99,
1611-1625,
2015
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https://doi.org/10.1007/s00253-014-6346-7
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Tomislav Cernava, Ines Aschenbrenner, Jung Soh, Stephan Fuchs, Katharina Riedel, Christoph Wilhelm Sensen, Martin Grube and Gabriele Berg Functioning of lichen symbioses is supported by a diversified bacterial microbiome
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Christian Lembacher-Fadum, Jakov Ivkovic, Shalinee Jha, Prashant Kumar, Karl Gruber, Peter Macheroux and Rolf Breinbauer Design and Synthesis of Inhibitors of Dipeptidyl Peptidase-III
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UM Tran, U. Rajarajacholan, Jung Soh, TS Kim, S. Thalappilly, Christoph Wilhelm Sensen and Karl Riabowol
LincRNA-p21 acts as a mediator of ING1b-induced apoptosis
Cell Death & Disease
6,
e1668-e1668,
2015
DOI:
https://doi.org/10.1038/cddis.2015.15
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Margit Winkler, Katharina Dokulil, Hansjörg Weber, Tea Pavkov-Keller and Birgit Wilding
The Nitrile forming Enzyme 7-Cyano-7-deazaguanine Synthase from Geobacillus kaustophilus: A reverse Nitrilase?
ChemBioChem
16,
2373-2378,
2015
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https://doi.org/10.1002/cbic.201500335
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Margit Winkler
Drug Metabolite Synthesis with Human Enzymes
International pharmaceutical industry
7,
32-36,
2015
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Tomislav Cernava, Ines Aschenbrenner, Armin Erlacher, Jung Soh, Stephan Fuchs, Katharina Riedel, Christoph Wilhelm Sensen, Martin Grube and Gabriele Berg Deciphering functional roles and beneficial contributions of the lichen-associated bacterial microbiome
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Martina Geier, Pia Carina Fauland, Thomas Vogl and Anton Glieder
Compact multi-enzyme pathways in P. pastoris
Chemical Communications
15,
1643-1646,
2015
DOI:
https://doi.org/10.1039/c4cc08502g
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Bettina Halwachs, René Snajder, Gregor Gorkiewicz and Gerhard Thallinger Decontaminator: detection and removal of contaminating sequences of unknown source
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Harald Pichler Biotechnology of Cellular Membranes - Biosynthesis, Interactions and Functions of Hydrophobic Compounds
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Jillian M. Hagel, Jeremy S. Morris, Eun-Jeong Lee, Isabel Desgagne-Penix, Crystal D. Bross, Limei Chang, Xue Chen, Scott C. Farrow, Ye Zhang, Jung Soh, Christoph Wilhelm Sensen and Peter J. Facchini
Transcriptome analysis of 20 taxonomically related benzylisoquinoline alkaloid-producing plants.
BMC Plant Biology
15,
227-243,
2015
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https://doi.org/10.1186/s12870-015-0596-0
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Sandy Schmidt, Christian Scherkus, Jan Muschiol, Ulf Menyes, Till Winkler, Werner Hummel, Harald Gröger, Andreas Liese, Hans Georg Herz and Uwe T. Bornscheuer
Eine Enzymkaskade zur Synthese von ε-Caprolacton und dessen Oligomeren
Angewandte Chemie
127,
2825-2828,
2015
DOI:
https://doi.org/10.1002/ange.201410633
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Ivan Hajnal, Melanie Hall, Matthias Fink, Kurt Faber, Helmut Schwab and Kerstin Steiner Oxidative alkene cleavage activities among proteins with cupin fold
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Kerstin Steiner, Romana Wiedner, Bettina Kothbauer, Mandana Gruber and Helmut Schwab Engineering of cupin hydroxynitrile lyases
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M. Pichler, A. L. Ress, E. Winter, V. Stiegelbauer, M. Karbiener, D. Schwarzenbacher, M. Scheideler, C. Ivan, S. W. Jahn, T. Kiesslich, A. Gerger, T. Bauernhofer, G. A. Calin and G. Hoefler
MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients
British Journal of Cancer
110,
1614-1621,
2014
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https://doi.org/10.1038/bjc.2014.51
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Bettina Halwachs, Andreas Braun, Andrea Camattari, Anton Glieder and Gerhard Thallinger MuteinDB: a database of enzyme variants linked to substrates, products, and enzymatic reaction properties using a standardized input format
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Michael Karbiener, Didier Pisani, Andrea Frontini, Lisa Maria Oberreiter, Eleonore Lang, Alexandros Vegiopoulos, Karin Mössenböck, Gerwin Bernhardt, Florian Hildner, Johannes Grillari, Gérard Ailhaud, Stephan Herzig, Saverio Cinti, Ez-Zoubir Amri and Marcel Scheideler miR-26a and miR-26b as key regulators of human white and brite adipocyte differentiation
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Romana Wiedner, Mandana Gruber-Khadjawi, Helmut Schwab and Kerstin Steiner
Discovery of a novel (R)-selective bacterial cupin HNL from Acidobacterium capsulatum ATCC 51196 by a sequence-based approach
Computational and Structural Biotechnology Journal
10,
58-62,
2014
DOI:
https://doi.org/10.1016/j.csbj.2014.07.002
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Kerstin Steiner and Helmut Schwab The potential of enzymes with cupin fold in biocatalysis
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Bernd Albrecht, Barbara Petschacher, Holly Stolterfoht, Katharina Littringer, Martin Lehmann, Hans-Peter Hohmann and Harald Pichler Characterizing microbial and mammalian acyl-transferases in a cholesterol-producing yeast strain
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Romana Wiedner, Bettina Kothbauer, Tea Pavkov-Keller, Mandana Gruber, Simone Petek, Karl Gruber, Helmut Schwab and Kerstin Steiner Engineered bacterial hydroxynitrile lyases, a promising new source of sustainable biocatalysts
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Tibor Czabany, Katharina Schmoelzer, Doris Ribitsch, Christiane Luley, Helmut Schwab and Bernd Nidetzky Mechanism and application of bacterial sialyltransferase
Alternative link: Link
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Martina Geier, Christoph Brandner and Anton Glieder Pichia pastoris with improved NADH regeneration: A novel platform strain for whole-cell biocatalysis
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Alexander Deutsch, Beate Rinner, Kerstin Wenzl, Martin Pichler, Katharina Troppan, Elisabeth Steinbauer, Daniela Schwarzenbacher, Sonja Reitter, Julia Feichtinger, Sascha Tierling, Andreas Prokesch, Marcel Scheideler, Anne Krogsdam, Gerhard Thallinger, Helmut Schaider, Christine Beham-Schmid and Peter Neumeister
NR4A1-mediated apoptosis suppresses lymphomagenesis and is associated with a favorable cancer-specific survival in patients with aggressive B-cell lymphomas
Blood
123,
2367-2377,
2014
DOI:
https://doi.org/10.1182/blood-2013-08-518878
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Elisa Lanfranchi, Anton Glieder and Margit Winkler Novel enzymes for Biocatalysis
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Filippo Fiorentini, Melanie Hall, Margit Winkler, Martina Geier, Claudia Binda, Kurt Faber and Andrea Mattevi Preliminary characterization of hFMO5. A human Bayer-Villiger Monooxygenase?
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Kerstin Steiner, Melanie Hall, Ivan Hajnal and Helmut Schwab NOVEL OXIDATIVE ACTIVITIES AMONG PROTEINS WITH CUPIN FOLD
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Steven P. Hanlon, Matthias Kittelmann and Margit Winkler SEMI-PREPARATIVE SCALE DRUG METABOLITE SYNTHESIS WITH HUMAN FLAVIN MONOOXYGENASESPractical Methods in Biocatalysis and Biotransformations135-139
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Thorsten Bachler, Marcia Antunes, Fabian K. Eggimann, Matthias Kittelmann, Stephan Lütz, Steven Hanlon, Beat Wirz, Andrea Camattari and Margit Winkler Human Xanthin Oxidase: Expression In E. coli and Drug Metabolite Synthesis
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Michael Karbiener, Didier Pisani, Andrea Frontini, Lisa Maria Oberreiter, Eleonore Lang, Alexandros Vegiopoulos, Karin Mössenböck, Gerwin Bernhardt, Florian Hildner, Johannes Grillari, Gérard Ailhaud, Stephan Herzig, Saverio Cinti, Ez-Zoubir Amri and Marcel Scheideler MicroRNA-26 family is required for human adipogenesis and drives characteristics of brown adipocytes
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Andrea Mellitzer, Claudia Ruth, Claes Gustafson, Mark Welch, Ruth Birner-Gruenberger, Roland Weis, Thomas Purkarthoer and Anton Glieder
Synergistic modular promoter and gene optimization to push cellulase secretion by Pichia pastoris beyond existing benchmarks
Journal of Biotechnology
191,
187-195,
2014
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https://doi.org/10.1016/j.jbiotec.2014.08.035
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Aleksandra Mitrovic and Anton Glieder Discovery of fungal enzymes and pathwaysFungal Bio-Molecules: Sources, Applications and Recent Developments51-61
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Martina Geier, Thorsten Bachler, Fabian Eggimann, Diogo Rodrigues, Steven Hanlon, Beat Wirz, Matthias Kittelmann, Stephan Lütz, Anton Glieder and Margit Winkler Generating a Platform of Human Non-CYP Drug Metabolizing Enzymes for API Modification
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Florian Krainer, Robert Pletzenauer, Laura Rossetti, Christoph Herwig, Anton Glieder and Oliver Spadiut
Purification and basic biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris.
Protein expression and purification
95,
104-112,
2014
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https://doi.org/doi: 10.1016/j.pep.2013.12.003
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Tamara Wriessnegger, Peter Andreas Augustin, Matthias Engleder, Erich Leitner, Monika Müller, Iwona Kaluzna, Martin Schürmann, Daniel Mink, Günther Zellnig, Helmut Schwab and Harald Pichler
Production of the sesquiterpenoid (+)-nootkatone by metabolic engineering of Pichia pastoris
Metabolic Engineering
24,
18-29,
2014
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https://doi.org/10.1016/j.ymben.2014.04.001
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Michael Karbiener, Christina Glantschnig and Marcel Scheideler
Hunting the needle in the haystack - A guide to obtain biologically meaningful microRNA targets
International Journal of Molecular Sciences
15,
20266-20289,
2014
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https://doi.org/10.3390/ijms151120266
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Ludger Wessjohann, Martin Dippe, Martin Tengg and Mandana Gruber Methyltransferases in biocatalysisCascade Biocatalysis: Stereoselective and Environmentally Friendly Reactions
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Ahmad Mudassar, Melanie Hirz, Harald Pichler and Helmut Schwab
Protein expression in Pichia pastoris: recent achievements and perspectives for heterologous protein production
Applied Microbiology and Biotechnology
98,
5301-5317,
2014
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https://doi.org/10.1007/s00253-014-5732-5
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Ronald Gstir, Simon Schafferer, Marcel Scheideler, Matthias Misslinger, Matthias Griehl, Nina Daschil, Christian Humpel, Gerald J. Obermair, Claudia Schmuckermair, Joerg Striessnig, Bernhard E. Flucher and Alexander Hüttenhofer
Generation of a neuro-specific microarray reveals novel differentially expressed noncoding RNAs in mouse models for neurodegenerative diseases
RNA
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https://doi.org/10.1261/rna.047225.114
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Doris Ribitsch, Sabine Zitzenbacher, Peter Andreas Augustin, Katharina Schmoelzer, Christiane Luley, Marco Thomann, Christine Jung, Harald Sobek, Rainer Müller, Bernd Nidetzky and Helmut Schwab
High-quality production of human α-2,6-sialyltransferase in Pichia pastoris requires control over N-terminal truncations by host-inherent protease activities
Microbial Cell Factories
13,
138-149,
2014
DOI:
https://doi.org/10.1186/s12934-014-0138-8
Alternative link: Link
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Petra Köfinger, Zalina Magomedova, Christina Zach, Steffen Gruber and Helmut Schwab Homologous and heterologous expression of dehydrogenases and oxidoreductases of Ralstonia eutropha H16
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Barbara Petschacher, Nicole Staunig, Monika Mueller, Martin Schuermann, Daniel Mink, Stefaan Wildemann, Karl Gruber and Anton Glieder
Cofactor Specificity Engineering of Streptococcus mutans NADH Oxidase 2 for NAD (P)+ Regeneration in Biocatalytic Oxidations
Computational and Structural Biotechnology Journal
9,
1-11,
2014
DOI:
https://doi.org/10.5936/csbj.201402005
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Tamara Wriessnegger, Anita Emmerstorfer, Melanie Hirz, Peter Andreas Augustin, Matthias Engleder, Gerald Richter and Harald Pichler Heterologous expression of membrane proteins in engineered yeasts - (+)-nootkatone production in yeasts
Show publication in PURE
Christiane Luley, Katharina Schmoelzer, Doris Ribitsch, Tibor Czabany, [No Value] Deja Kokot, Andrzej Franciszek Lyskowski, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis carries a natural Ser-to-Thr substitution
Show publication in PURE
Julia Pitzer New promoters and terminators for Pichia pastoris
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Margit Winkler, Martina Geier, Thorsten Bachler, Steven Hanlon, Matthias Kittelmann, Anton Glieder, Stephan Lütz and Beat Wirz Human flavin monooxygenase 2: Heterologous expression in E. coli and API modification
Show publication in PURE
Tomislav Cernava, Ines Aschenbrenner, Jung Soh, Stephan Fuchs, Christian Lassek, Uwe Wegner, Katharina Riedel, Christoph W. Sensen, Martin Grube and Gabriele Berg Longevity and sustainability of lichen symbioses are supported by a stable and versatile microbiome
Alternative link: Link
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Matthias Hackl, Vaibhav Jadhav, Gerald Klanert, Michael Karbiener, Marcel Scheideler, Johannes Grillari and Nicole Borth
Analysis of microRNA transcription and post-transcriptional processing by Dicer in the context of CHO cell proliferation
Journal of Biotechnology
190,
76–84,
2014
DOI:
https://doi.org/10.1016/j.jbiotec.2013.12.018
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Margit Winkler, Kamilla Napora-Wijata, Birgit Wilding and Norbert Klempier Unconventional Enzymatic Reductions: Nitriles and Carboxylates as Substrates
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Tea Pavkov-Keller, Alexandra Binter, Georg Steinkellner, Christian C. Gruber, Kerstin Steiner, Christoph Winkler, Helmut Schwab, Kurt Faber, Peter Macheroux and Karl Gruber Structural and biochemical characterization of two novel enzymes with promiscuous ene-reductase activity
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Aleksandra Mitrovic, Karlheinz Flicker, Georg Steinkellner, Karl Gruber, Christoph Reisinger, Christoph Schirrmacher, Andrea Camattari and Anton Glieder
Thermostability improvement of endoglucanase Cel7B from Hypocrea pseudokoningii
Journal of Molecular Catalysis B
103,
16-23,
2014
DOI:
https://doi.org/10.1016/j.molcatb.2013.12.009
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Katharina Schmoelzer, Christiane Luley, Tibor Czabany, Doris Ribitsch, Helmut Schwab, Hansjörg Weber and Bernd Nidetzky
Mechanistic study of CMP-Neu5Ac hydrolysis by α2,3-sialyltransferase from Pasteurella dagmatis
FEBS Letters
588,
2978-2984,
2014
DOI:
https://doi.org/10.1016/j.febslet.2014.05.053
Alternative link: Link
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Steffen Gruber, Jeremias Hagen, Helmut Schwab and Petra Köfinger
Versatile and stable vectors for efficient gene expression in Ralstonia eutropha H16
Journal of Biotechnology
186,
74-82,
2014
DOI:
https://doi.org/10.1016/j.jbiotec.2014.06.030
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Thomas Vogl, Gerhard Thallinger, Günther Zellnig, David Drew, James Cregg, Anton Glieder and Maria Elisabeth Freigaßner
Towards improved membrane protein production in Pichia pastoris: general and specific transcriptional response to membrane protein overexpression
New Biotechnology
31,
538-552,
2014
DOI:
https://doi.org/10.1016/j.nbt.2014.02.009
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Katrin Weinhandl, Margit Winkler, Anton Glieder, Ian Fotheringham, Franck Escalettes and Andrea Camattari Extracellular transaminases for biocatalysis
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Thomas Brück, Robert Kourist and Bernhard Loll
Production of macrocyclic sesqui‐and diterpenes in heterologous microbial hosts: A systems approach to harness Nature’s molecular diversity
ChemCatChem
6,
1142-1165,
2014
DOI:
https://doi.org/10.1002/cctc.201300733
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Michael Karbiener, Didier Pisani, Andrea Frontini, Lisa Maria Oberreiter, Eleonore Lang, Alexandros Vegiopoulos, Karin Mössenböck, Gerwin Bernhardt, Florian Hildner, Johannes Grillari, Gérard Ailhaud, Stephan Herzig, Saverio Cinti, Ez-Zoubir Amri and Marcel Scheideler miR-26a and miR-26b as key regulators of human white and brite adipocyte differentiation
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Tamara Wriessnegger, Anita Emmerstorfer, Peter Andreas Augustin, Matthias Engleder, Monika Müller, Iwona Kaluzna, Helmut Schwab and Harald Pichler (+)-Nootkatone production in yeasts
Show publication in PURE
Holly Stolterfoht, Barbara Petschacher, Katharina Littringer, Florian Ungerböck, Corinna Odar, Martin Lehmann, Hans-Peter Hohmann and Harald Pichler Characterizing the Sterol Specificity of Microbial and Mammalian Acyltransferases
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Robert Kourist, Jan-Karl Guterl, Kenji Miyamoto and Volker Sieber
Enzymatic decarboxylation—an emerging reaction for chemicals production from renewable resources
ChemCatChem
6,
689-701,
2014
DOI:
https://doi.org/10.1002/cctc.201300881
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Tamara Wriessnegger, Anita Emmerstorfer, Monika Müller, Iwona Kaluzna, Helmut Schwab and Harald Pichler (+)-Nootkatone production in yeasts
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Katrin Weinhandl, Margit Winkler, Anton Glieder and Andrea Camattari
Carbon source dependent promoters in yeasts
Microbial Cell Factories
13,
5-21,
2014
DOI:
https://doi.org/10.1186/1475-2859-13-5
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R Kourist, F. Hollmann and G. S. Nguyen
Lipases as Sustainable Biocatalysts for the Sustainable Industrial Production of Fine Chemicals and Cosmetics
JSM Biotechnology & Biomedical Engineering
2,
1029,
2014
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Diogo Rodrigues, Matthias Kittelmann, Fabian Eggimann, Thorsten Bachler, Sandra Abad, Andrea Camattari, Anton Glieder, Margit Winkler and Stephan Lütz
PRODUCTION OF RECOMBINANT HUMAN ALDEHYDE OXIDASE IN E. COLI AND OPTIMIZATION OF ITS APPLICATION FOR PREPARATIVE SYNTHESIS OF OXIDIZED DRUG METABOLITES
ChemCatChem
6,
1028-1042,
2014
DOI:
https://doi.org/10.1002/CCTC.201301094
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Margit Winkler, Kamilla Napora-Wijata, Birgit Wilding and Norbert Klempier Enzymatic Reductions of unconventioal substrates: Carboxylates and Nitriles
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Eva-Maria Köhler, Elisa Lanfranchi, Kerstin Steiner, Barbara Darnhofer, Ruth Birner-Grünberger, Anton Glieder and Margit Winkler Bioprospecting for new hydroxynitrile lyases using blue native PAGE coupled in-gel activity assay
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Georg Steinkellner, Christian C. Gruber, Tea Pavkov-Keller, Alexandra Binter, Kerstin Steiner, Christoph Winkler, Andrzej Lyskowski, Orsolya Schwamberger, Monika Oberer, Helmut Schwab, Kurt Faber, Peter Macheroux and Karl Gruber
Identification of promiscuous ene-reductase activity by mining structural databases using active site constellations
Nature Communications
5,
1-9,
2014
DOI:
https://doi.org/10.1038/ncomms5150
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Martina Geier, Thomas Vogl, Lukas Sturmberger, Christian Schmid, Birgit Wiltschi and Anton Glieder New tools for pathway generation employing the concepts of synthetic biology
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Michael Karbiener, Didier Pisani, Andrea Frontini, Lisa Maria Oberreiter, Eleonore Lang, Alexandros Vegiopoulos, Karin Mössenböck, Gerwin Bernhardt, Torsten Mayr, Florian Hildner, Johannes Grillari, Gerard Ailhaud, Stephan Herzig, Saverio Cinti, Ez-Zoubir Amri and Marcel Scheideler
MicroRNA-26 family is required for human adipogenesis and drives brown adipocytes characteristics
Stem Cells
32,
1578-1590,
2014
DOI:
https://doi.org/10.1002/stem.1603
Alternative link: Link
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Gerlinde Offenmüller, Katrin Weinhandl, Melanie Ballach, Margit Winkler, Anton Glieder, Ian Fotheringham, Franck Escalettes and Andrea Camattari Pichia pastoris for efficient production of extracellular transaminases
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L Hilterhaus and R Kourist Microbial Lactone Synthesis Based on Renewable Resources
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Ronald Gstir, Simon Schafferer, Marcel Scheideler, M Misslinger, Matthias Griehl, N Daschil, C Humpel, GJ Obermair, C Schuckermair, J Striessnig, BE Flucher and Alexander Hüttenhofer
Generation of a neuro-specific microarray reveals novel differentially expressed noncoding RNAs in mouse models for neurodegenerative diseases.
RNA
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1929-1943,
2014
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https://doi.org/10.1261/rna.047225.114
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Katharina Schmoelzer, Doris Ribitsch, Tibor Czabany, Christiane Luley, Deja Kokot, Andrzej Franciszek Lyskowski, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution
Show publication in PURE
Oliver Spadiut, Simona Capone, Florian Krainer, Anton Glieder and Christoph Herwig
Microbials for the production of monoclonal antibodies and antibody fragments
Trends in Biotechnology
32,
54-60,
2014
DOI:
https://doi.org/10.1016/j.tibtech.2013.10.002
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Thomas Vogl Synthetic promoters enabling novel gene co-expression strategies
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Ryan Lauchli, Julia Pitzer, Rebekah Z. Kitto, Karolina Z. Kalbarczyk and Kersten S. Rabe
Improved selectivity of an engineered multi-product terpene synthase
Organic & biomolecular chemistry
12,
4013-4020,
2014
DOI:
https://doi.org/10.1039/c4ob00479e
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Anita Emmerstorfer, Tamara Wriessnegger, Melanie Hirz and Harald Pichler
Overexpression of membrane proteins from higher eukaryotes in yeasts
Applied Microbiology and Biotechnology
98,
7671-7698,
2014
DOI:
https://doi.org/10.1007/s00253-014-5948-4
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Elisa Lanfranchi, Eva-Maria Köhler, Kerstin Steiner, Anton Glieder and Margit Winkler Blue Native PAGE: bioprospecting for new hydroxynitrile lyases
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Florian W. Krainer, Robert Pletzenauer, Laura Rossetti, Christoph Herwig, Anton Glieder and Oliver Spadiut
Purification and basic biochemical characterization of 19 recombinant plant peroxidase isoenzymes produced in Pichia pastoris
Protein Expression and Purification
95,
104-112,
2014
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https://doi.org/10.1016/j.pep.2013.12.003
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Laura Näätsaari, Florian Krainer, Michael Schubert, Anton Glieder and Gerhard G. Thallinger
Peroxidase gene discovery from the horseradish transcriptome
BMC Genomics
15,
227-227,
2014
DOI:
https://doi.org/10.1186/1471-2164-15-227
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Michael Karbiener, Didier Pisani, Andrea Frontini, Lisa Maria Oberreiter, Eleonore Lang, Alexandros Vegiopoulos, Karin Mössenböck, Gerwin Bernhardt, Florian Hildner, Johannes Grillari, Gérard Ailhaud, Stephan Herzig, Saverio Cinti, Ez-Zoubir Amri and Marcel Scheideler MicroRNA-26 family is required for human adipogenesis and drives brown adipocyte characteristics
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Katrin Weinhandl, Margit Winkler, Anton Glieder and Andrea Camattari Extracellular transaminases for biocatalysisNew BiotechnologyS198-S198
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Margit Winkler, Kamilla Napora-Wijata, Birgit Wilding and Norbert Klempier Unconventional Enzymatic Reductions: Nitriles and Carboxylates as SubstratesNew BiotechnologyS1-S2
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Dietmar Rieder, Christian Ploner, Anne M. Krogsdam, Gernot Stocker, Maria Fischer, Marcel Scheideler, Christian Dani, Ez Zoubir Amri, Waltraud G. Müller, James G. McNally and Zlatko Trajanoski
Co-expressed genes prepositioned in spatial neighborhoods stochastically associate with SC35 speckles and RNA polymerase II factories
Cellular and Molecular Life Sciences
71,
1741-1759,
2014
DOI:
https://doi.org/10.1007/s00018-013-1465-3
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Florian Krainer, McLean Kirsty, Joseph Hosford, Lu Shin Wong, Andrew W Munro and Anton Glieder Characterization of recombinant horseradish peroxidase isoenzymes from Pichia pastoris
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Margit Winkler, Martina Geier, Thorsten Bachler, Steven P Hanlon, Matthias Kittelmann, Anton Glieder, Stephan Lütz and Beat Wirz Human flavin monooxygenase 2: Heterologous expression in E. coli and API modificationNew BiotechnologyS82-S82
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Michael Karbiener and Marcel Scheideler
MicroRNA functions in brite/brown fat - novel perspectives towards anti-obesity strategies
Computational and Structural Biotechnology Journal
11,
101-105,
2014
DOI:
https://doi.org/10.1016/j.csbj.2014.09.005
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Wolf-Dieter Lienhart, Venugopal Gudipati, Michael K. Uhl, Alexandra Binter, Sergio A. Pulido, Robert Saf, Klaus Zangger, Karl Gruber and Peter Macheroux
Collapse of the native structure caused by a single amino acid exchange in human NAD(P)H:quinone oxidoreductase1
The FEBS Journal
281,
4691-4704,
2014
DOI:
https://doi.org/10.1111/febs.12975
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Marcel Scheideler, Michael Karbiener, Eleonore Lang, Lisa Maria Oberreiter, Christina Glantschnig, Didier Pisani, Gérard Ailhaud and Ez-Zoubir Amri MicroRNA functions in human fat cell development - Novel perspectives towards anti-obesity strategiesBIT´s Annual World Congress of Molecular & Cell Biology - 2014124-124
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Shuke Wu, Yongzheng Chen, Yi Xu, Aitao Li, Qisong Xu, Anton Glieder and Zhi Li
Enantioselective trans-dihydroxylation of aryl olefins by cascade biocatalysis with recombinant escherichia coli coexpressing monooxygenase and epoxide hydrolase
ACS Catalysis
4,
409-420,
2014
DOI:
https://doi.org/10.1021/cs400992z
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Romana Wiedner, Bettina Kothbauer, Mandana Gruber, Helmut Schwab and Kerstin Steiner Engineering of cupin hydroxynitrile lyases
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Florian Krainer, Kirsty McLean, Joseph Hosford, Lu Shin Wong, Andrew W Munro and Anton Glieder Characterization of recombinant horseradish peroxidase isoenzymes from Pichia pastoris
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Tomislav Cernava, Ines Aschenbrenner, Katharina Riedel, Jung Soh, Christoph W. Sensen, Martin Grube and Gabriele Berg Deciphering a functional network of symbiotic sustain with the microbiome of lichens by comparative omics
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Kerstin Steiner, Andrzej Franciszek Lyskowski, Christian Gruber, Georg Steinkellner, Martin Schurmann, Helmut Schwab and Karl Gruber Crystal structure of an (R)-selective ω-transaminase from Aspergillus terreus
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Thomas Vogl, Claudia Ruth, Julia Pitzer, Thomas Kickenweiz and Anton Glieder
Synthetic Core Promoters for Pichia pastoris
ACS Synthetic Biology
3,
188–191,
2014
DOI:
https://doi.org/10.1021/sb400091p
Alternative link: Link
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Martin Pichler, Anna Ress, Elke Winter, Verena Stiegelbauer, Michael Karbiener, Daniela Schwarzenbacher, Marcel Scheideler, Cristina Ivan, Stephan Jahn, Tobias Kiesllich, Armin Gerger, Thomas Bauernhofer, George Calin and Gerald Höfler
MiR-200a regulates epithelial to mesenchymal transition-related gene expression and determines prognosis in colorectal cancer patients
British Journal of Cancer
110,
1614-1621,
2014
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Andreas Maccani, Matthias Hackl, Christian Leitner, Nadine E. Tatto, Michael Karbiener, Marcel Scheideler, Johannes Grillari, Diethard Mattanovich, Renate Kunert, Nicole Borth, Reingard Grabherr and Wolfgang Ernst
Identification of microRNAs specific for high producer CHO cell lines using steady-state cultivation
Applied Microbiology and Biotechnology
98,
7535-7548,
2014
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Julia Pitzer Novel mono- and bidirectional promoters in three different yeasts
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Andrea Camattari, Gerlinde Offenmüller, Katrin Weinhandl, Melanie Ballach, Margit Winkler, Ian Fotheringham, Franck Escalettes and Anton Glieder Secretion of transaminase in Pichia pastoris
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Kamila Napora, Gernot Strohmeier and Margit Winkler
Biocatalytic reduction of carboxylic acids
Biotechnology Journal
9,
822-843,
2014
DOI:
https://doi.org/10.1002/biot.201400012
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Florian Krainer, Kirsty McLean, Joseph Hosford, Lu Shin Wong, Andrew W Munro and Anton Glieder Characterization of recombinant horseradish peroxidase isoenzymes from Pichia pastoris
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Matthias Diepold, Tea Pavkov-Keller, Elisa Lanfranchi, Anton Glieder, Kerstin Steiner, Margit Winkler and Karl Gruber Structural studies on the hydroxynitrile lyase from Davallia tyermanii
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Andrzej Franciszek Lyskowski, Christian Gruber, Georg Steinkellner, M Schuermann, Helmut Schwab, Karl Gruber and Kerstin Steiner
Crystal structure of an (R)-selective ω-transaminase from Aspergillus terreus (R)-selective ω-transaminase from Aspergillus terre
PLoS ONE
9,
1-9,
2014
DOI:
https://doi.org/10.1371/journal.pone.0087350
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Thorsten Bachler, Steven P. Hanlon, Matthias Kittelmann, Martina Geier, Andrea Camattari, Anton Glieder, Beat Wirz, Stephan Lütz and Margit Winkler Human Flavin Monooxygenases as a Tool for Drug Metabolite Synthesis
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Thomas Vogl and Anton Glieder
Regulation of Pichia pastoris promoters and its consequences for protein production
New Biotechnology
30,
385-404,
2013
DOI:
https://doi.org/10.1016/j.nbt.2012.11.010
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Kamila Napora, Manoj N. Sonavane, Jacek Plewka, Dorota K. Pomorska, Karen Robins, Antonio Osorio-Lozada, Kerstin Steiner, Helmut Schwab and Margit Winkler Carboxylate reductase - a novel route for 3-hydroxytyrosol production
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Birgit Wilding, Barbara Petschacher, Margit Winkler, Gerlinde Offenmüller, Georg Steinkellner, Andrzej Franciszek Lyskowski, Regina Kratzer, Karl Gruber, Bernd Nidetzky and Norbert Klempier Enzymatic Nitrile Reduction
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Ivan Hajnal, Andrzej Franciszek Lyskowski, Ulf Hanefeld, Karl Gruber, Helmut Schwab and Kerstin Steiner
Biochemical and structural characterization of a novel bacterial manganese-dependent hydroxynitrile lyase
The FEBS Journal
280,
5815-5828,
2013
DOI:
https://doi.org/10.1111/febs.12501
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Thorsten Bachler, Diogo F. Rodrigues, Matthias Kittelmann, Martina Geier, Sandra Abad, Steven P. Hanlon, Andrea Camattari, Stephan Lütz, Beat Wirz and Margit Winkler Towards drug metabolite production on the multi-miligram scale: Generation of an efficient aldehyde oxidase (AOX1) based biocatalyst
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Enrique Herrero Acero, Doris Ribitsch, Karolina Hårnvall, Georg Steinkellner, Karl Gruber, Helmut Schwab and Georg Gübitz Increasing polyesterase activity towards synthetic polymers by diverse molecular approaches
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Doris Ribitsch, Orcal Yebra Antonio, Sabine Zitzenbacher, Jing Wu, Susanne Nowitsch, Georg Steinkellner, Katrin Julia Greimel, Doliška Aleš, Gustav Oberdorfer, Christian Gruber, Karl Gruber, Helmut Schwab, Stana-Kleinschek Karin, Enrique Herrero Acero and Georg Gübitz
Fusion of binding-domains to Thermobifida cellulosilytica cutinase to tune sorption characteristics and enhancing PET hydrolysis
Biomacromolecules
14,
1769–1776,
2013
DOI:
https://doi.org/10.1021/bm400140u
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Kerstin Steiner, Ivan Hajnal and Helmut Schwab Cupins, a versatile family of metalloenzymes
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Martina Geier, Andreas Braun, Patrick Fladischer, Piotr Stepniak, Florian Rudroff, Christoph Hametner, Marko Mihovilovic and Anton Glieder
Double site saturation mutagenesis of the human cytochrome P450 2D6 results in regioselective steroid hydroxylation
The FEBS Journal
280,
3094-108,
2013
DOI:
https://doi.org/10.1111/febs.12270
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Enrique Herrero Acero, Doris Ribitsch, Annemarie Marold, Katrin Julia Greimel, Georg Steinkellner, Karl Gruber, Helmut Schwab and Georg Gübitz The role of surface amino acids on cutinases is a key to tune hydrolysis of polyethylene terephthalate
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Kamila Napora, Tanja Wrodnigg, Patrick Kosmus, Martin Thonhofer, Manoj N. Sonavane, Dorota K. Pomorska, Thomas Prossliner, Karen Robins and Margit Winkler Mannitol dehydrogenase as a tool for enzymatic oxidation of lipophilic substrates: alcohols and sugar alcohols
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Katrin Weinhandl, Jacek Plewka, Margit Winkler, Anton Glieder, Ian Fotheringham and Andrea Camattari Secretive expression of bacterial BCAT in Pichia pastoris
Alternative link: Link
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Tibor Czabany, Katharina Schmoelzer, Doris Ribitsch, Christiane Luley, Deja Kokot, Andrzej Franciszek Lyskowski, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis PdST carries a natural Ser-to-Thr substitution
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Florian W. Krainer, Christoph Gmeiner, Lukas Neutsch, Markus Windwarder, Robert Pletzenauer, Christoph Herwig, Friedrich Altmann, Anton Glieder and Oliver Spadiut
Knockout of an endogenous mannosyltransferase increases the homogeneity of glycoproteins produced in Pichia pastoris
Scientific Reports
3,
3279-3291,
2013
DOI:
https://doi.org/10.1038/srep03279
Alternative link: Link
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Elisa Lanfranchi, Kerstin Steiner, Barbara Darnhofer, Ruth Birner-Grünberger, Anton Glieder and Margit Winkler A new hydroxynitrile lyase from fern: from the plant to the sequence
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Martina Geier and Anton Glieder Protein Engineering Using Eukaryotic Expression SystemsProtein Engineering Handbook - Volume 347-72
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Birgit Wilding, Barbara Petschacher, Margit Winkler, Gerlinde Offenmüller, Regina Kratzer, Georg Steinkellner, Andrzej Franciszek Lyskowski, Karl Gruber, Bernd Nidetzky and Norbert Klempier Exploring the Active Binding Site of Nitrile Reductases
Alternative link: Link
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Tamara Wriessnegger, Melanie Hirz, Gerald Richter and Harald Pichler Functional expression of human Na,K-ATPase α3β1 isoform in a cholesterol producing Pichia pastoris strain
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Kamila Napora, Manoj N. Sonavane, Jacek Plewka, Dorota K. Pomorska, Karen Robins, Antonio Osorio-Lozada, Kerstin Steiner, Helmut Schwab and Margit Winkler The natural way to a natural product - microbial production of 3-hydroxytyrosol
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Martina Geier, Manuela Killinger, Birgit Wiltschi, Mandana Gruber-Khadjawi, Kateryna Lypetska, Gernot Strohmeier, Rolf Breinbauer, Nikolaus Turrini, Kurt Faber and Anton Glieder ACIB and CHEM21: Towards greener and more sustainable pharmaceutical manufacturing processes
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Petra Köfinger, Zalina Magomedova, Christina Zach and Helmut Schwab Homologous and heterologous expression of dehydrogenases and oxidoreductases of Ralstonia eutropha H16
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Romana Wiedner, Bettina Kothbauer, Kerstin Steiner, Mandana Gruber and Helmut Schwab Discovery of new and improved hydroxynitrile lyases belonging to the cupin superfamily
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Martina Geier, Anna-Maria Hatzl, Andrea Mellitzer and Anton Glieder Integrative expression vectors for stable pathway construction in the yeast Schizosaccharomyces pombe
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Christine Winkler, Mudassar Ahmad, Peter Neugebauer, Helmut Schwab and Harald Pichler Probing the secretory pathway of the yeast Pichia pastoris
Alternative link: Link
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Katharina Tauber, Michael Fuchs, Johann H. Sattler, Julia Pitzer, Desiree Pressnitz, Dominik Koszelewski, Kurt Faber, Jan Pfeffer, Thomas Haas and Wolfgang Kroutil
Artificial Multi-Enzyme Networks for the Asymmetric Amination of sec-Alcohols
Chemistry - a European Journal
19,
4030-4035,
2013
DOI:
https://doi.org/10.1002/chem.201202666
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Tamara Wriessnegger, Anita Emmerstorfer, Monika Müller, Iwona Kaluzna, Helmut Schwab and Harald Pichler Terpenoid production in yeasts
Alternative link: Link
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Reina Wada, Takashi Kumon, Robert Kourist, Hiromichi Ohta, Daisuke Uemura, Shosuke Yoshida and Kenji Miyamoto
Thermally driven asymmetric domino reaction catalyzed by a thermostable esterase and its variants
Tetrahedron Letters
54,
1921-1923,
2013
DOI:
https://doi.org/10.1016/j.tetlet.2013.01.080
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Barbara Petschacher, Katharina Littringer, Florian Ungerböck, Corinna Odar, Holly Stolterfoht, Martin Lehmann, Hans-Peter Hohmann and Harald Pichler Sterol specificity of homologous and heterologous acyltransferases expressed in S. cerevisiae
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Melanie Hirz, Gerald Richter, Tamara Wriessnegger and Harald Pichler Functional expression of a human membrane transporter in a cholesterol-producing Pichia pastoris strain
Alternative link: Link
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Aashrita Rajagopalan, Markus Schober, Anita Emmerstorfer, Lucas Hammerer, Anna Migglautsch, Birgit Seisser, Silvia M Glück, Frank Niehaus, Jürgen Eck, Harald Pichler, Karl Gruber and Wolfgang Kroutil
Enzymatic aerobic alkene cleavage catalyzed by a Mn3+-dependent proteinase A homologue
ChemBioChem
14,
2427-2430,
2013
DOI:
https://doi.org/10.1002/cbic.201300601
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Melanie Hirz, Gerald Richter, Erich Leitner, Tamara Wriessnegger and Harald Pichler
A novel cholesterol-producing Pichia pastoris strain is an ideal host for functional expression of human Na,K-ATPase α3β1 isoform
Applied Microbiology and Biotechnology
97,
9465-9478,
2013
DOI:
https://doi.org/10.1007/s00253-013-5156-7
Alternative link: Link
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Katrin Weinhandl, Margit Winkler, Anton Glieder, Ian Fotheringham, Franck Escalettes and Andrea Camattari Bacterial transaminases for chiral amine synthesis - Expression and Secretion in Pichia pastoris
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Tamara Wriessnegger, Anita Emmerstorfer, Matthias Engleder, Monika Müller, Ivona Kaluzna, Helmut Schwab and Harald Pichler De novo production of flavor compounds by engineered yeasts
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Katharina Schmoelzer, Doris Ribitsch, Tibor Czabany, Christiane Luley, Deja Kokot, Andrzej Franciszek Lyskowski, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky Characterization of a multifunctional alpha2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution
Alternative link: Link
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Kerstin Steiner, Ivan Hajnal and Helmut Schwab Cupins as scaffolds for novel activities
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Mandana Gruber, Lisa Offner and Martin Tengg Biocatalytic Thiol Alkylation
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Katharina Schmoelzer, Doris Ribitsch, Tibor Czabany, Christiane Luley, Deja Kokot, Andrzej Franciszek Lyskowski, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky
Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis
Glycobiology
23,
1293-1304,
2013
DOI:
https://doi.org/10.1093/glycob/cwt066
Alternative link: Link
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Martina Geier, Christian Schmid and Anton Glieder Exploiting recombinant Pichia pastoris for drug metabolite synthesis: Towards an efficient CYP3A4-based whole-cell catalyst
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Gerlinde Offenmüller, Katrin Weinhandl, Margit Winkler, Anton Glieder, Ian Fotheringham, Franck Escalettes and Andrea Camattari Secretion of transaminases in Pichia pastoris: a basic module for efficient synthesis of chiral amines
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Kerstin Steiner, Martin Schurmann, Julia Midl, Stefaan De Wildeman, Peter Remler and Helmut Schwab A medium-throughput-screening method for the detection of the conversion of ketones by omega-transaminases
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Florian Krainer, Laura Näätsaari, Gerhard Thallinger, Christoph Herwig and Oliver Spadiut New horseradish peroxidase isoenzymes and their production in Pichia pastoris
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N. Mayer, M. Schweiger, M. Romauch, G.F. Grabner, T.O. Eichmann, E. Fuchs, J. Ivkovic, C. Heier, I. Mrak, A. Lass, G. Höfler, C. Fledelius, Rudolf Zechner, Robert Zimmermann and R. Breinbauer
Development of small-molecule inhibitors targeting adipose triglyceride lipase
Nature Chemical Biology
9,
785-787,
2013
DOI:
https://doi.org/10.1038/nchembio.1359
Alternative link: Link
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Felix G. Eikmeyer, Petra Köfinger, Andrea Poschenel, Sebastian Jünemann, Martha Zakrzewski, Stefan Heinl, Elisabeth Mayrhuber, Reingard Grabherr, Alfred Pühler, Helmut Schwab and Andreas Schlüter
Metagenome analyses reveal the influence of the inoculant Lactobacillus buchneri CD034 on the microbial community involved in grass ensiling
Journal of Biotechnology
167,
334-343,
2013
DOI:
https://doi.org/10.1016/j.jbiotec.2013.07.021
Alternative link: Link
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Kamila Napora, Tanja Wrodnigg, Patrick Kosmus, Martin Thonhofer, Karen Robins and Margit Winkler
Yarrowia lipolytica dehydrogenase/reductase: An enzyme tolerant for lipophilic compounds and carbohydrate substrates
Bioorganic & Medicinal Chemistry Letters
23,
3393-3395,
2013
DOI:
https://doi.org/10.1016/j.bmcl.2013.03.064
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Mandana Gruber, Lisa Offner and Martin Tengg Biocatalytic Thiol Alkylation
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Martin Tengg, Harald Stecher, Peter Remler, Helmut Schwab and Mandana Gruber Methyltransferase NovO - a Versatile Catalyst for Enzymatic Friedel-Crafts Alkylation
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Enrique Herrero Acero, Doris Ribitsch, Anita Dellacher, Sabine Zitzenbacher, Annemarie Marold, Georg Steinkellner, Karl Gruber, Helmut Schwab and Georg Gübitz
Surface engineering of a cutinase from Thermobifida cellulosilytica for improved polyester hydrolysis
Biotechnology and Bioengineering
110,
2581–2590,
2013
DOI:
https://doi.org/10.1002/bit.24930
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Katharina Schmoelzer, Doris Ribitsch, Tibor Czabany, Christiane Luley, Deja Kokot, Andrzej Franciszek Lyskowski, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky Characterization of a multifunctional α2,3-sialyltransferase from Pasteurella dagmatis, carrying a natural Ser-to-Thr substitution
Alternative link: Link
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Christine Winkler, Mudassar Ahmad, Peter Neugebauer, Helmut Schwab and Harald Pichler Probing the secretory pathway of the yeast Pichia pastorisBook of abstracts38-38
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Tamara Wriessnegger, Anita Emmerstorfer, Monika Müller, Iwona Kaluzna, Helmut Schwab and Harald Pichler Terpenoid production in yeastsBook of abstracts26-26
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Birgit Wilding, Margit Winkler, Barbara Petschacher, Regina Kratzer, Sigrid Egger, Georg Steinkellner, Andrzej Franciszek Lyskowski, Bernd Nidetzky, Karl Gruber and Norbert Klempier
Targeting the Substrate Binding Site of E. coli Nitrile Reductase QueF by Modeling, Substrate and Enzyme Engineering
Chemistry - a European Journal
19,
7007-7012,
2013
DOI:
https://doi.org/10.1002/chem.201300163
Alternative link: Link
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Mandana Gruber, Lisa Offner and Martin Tengg Biocatalytic Thiol Alkylation
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Elisa Lanfranchi, Kerstin Steiner, Anton Glieder, Ivan Hajnal, Roger A. Sheldon, Sander van Pelt and Margit Winkler
Mini-Review: Recent Developments in Hydroxynitrile Lyases for Industrial Biotechnology
Recent Patents on Biotechnology
7,
197-206,
2013
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Birgit Wilding, Barbara Petschacher, Margit Winkler, Regina Kratzer, Georg Steinkellner, Andrzej Franciszek Lyskowski, Karl Gruber, Bernd Nidetzky and Norbert Klempier Biological nitrile reduction – exploring a remarkable reaction
Alternative link: Link
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Elisa Lanfranchi, Pomorska Dorota Katarzyna, Steiner Kerstin, Helmut Schwab, Anton Glieder, Weis Rolan and Winkler Margit Recombinant hydroxynitrile lyase: high level expression in Pichia pastoris
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Thomas Vogl, Franz Stefan Hartner and Anton Glieder
New opportunities by synthetic biology for biopharmaceutical production in Pichia pastoris
Current Opinion in Biotechnology
24,
1094-1101,
2013
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https://doi.org/10.1016/j.copbio.2013.02.024
Alternative link: Link
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Alfred M Engel, Harald Sobek, Michael Greif, Sebastian Malik, Marco Thomann, Christine Jung, Dietmar Reusch, Doris Ribitsch, Sabine Zitzenbacher, Christiane Luley, Katharina Schmoelzer, Tibor Czabany, Bernd Nidetzky, Helmut Schwab and Rainer Mueller Rec. ST6Gal-I variants to control enzymatic activity in processes of in vitro glycoengineering
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Kateryna Fesko, Kerstin Steiner, Rolf Breinbauer, Helmut Schwab, Martin Schürmann and Gernot Strohmeier
Investigation of one-enzyme systems in the w-transaminase-catalyzed synthesis of chiral amines
Journal of Molecular Catalysis B
96,
103-110,
2013
DOI:
https://doi.org/10.1016/j.molcatb.2013.06.015
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Katharina Schmoelzer, Doris Ribitsch, Tibor Czabany, Christiane Luley, Deja Kokot, Andrzej Franciszek Lyskowski, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky A newly discovered multifunctional alpha2,3-sialyltransferase from Pasteurella dagmatis carries a natural Ser-to-Thr substitution
Alternative link: Link
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Georg Steinkellner, Christian Gruber, Kerstin Steiner, C. Winkler, Tea Pavkov-Keller, Alexandra Binter, A. Lyskowski, O. Schwamberger, Monika Oberer, Helmut Schwab, Kurt Faber, Peter Macheroux and Karl Gruber Novel enone-reductases identified by database mining for catalytic promiscuity
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Melanie Hirz, Gerald Richter, Tamara Wriessnegger and Harald Pichler Functional expression of a human membrane transporter in a cholesterol-producing Pichia pastoris strains
Alternative link: Link
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Christine Winkler, Ahmad Mudassar, Peter Neugebauer, Helmut Schwab and Harald Pichler Probing the secretory pathway of the yeast Pichia pastoris
Alternative link: Link
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Katharina Schmoelzer, Doris Ribitsch, Tibor Czabany, Christiane Luley, Deja Kokot, Andrzej Franciszek Lyskowski, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky A newly discovered multifunctional α2,3-sialyltransferase from Pasteurella dagmatis PdST carries a natural Ser-to-Thr substitution
Alternative link: Link
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Martina Geier, Christian Schmid and Anton Glieder
First functional expression of cytochrome P450 3A4 in Pichia pastoris
Chimica Oggi
31,
24-27,
2013
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Tamara Wriessnegger, Peter Augustin, Anita Emmerstorfer, Ariane Fankl, Monika Müller, Iwona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler Pichia pastoris as whole-cell biocatalyst for (+)-nootkatone production
Alternative link: Link
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Tamara Wriessnegger, Peter Augustin, Monika Müller, Ivona Kaluzna, Helmut Schwab and Harald Pichler Engineering of the yeast Pichia pastoris for high-level production of (+)-nootkatone
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Christine Winkler
Organaktivitäten im Schüttelkolben: Rekombinante menschliche Enzyme für die Pharmaindustrie
TU Graz Research
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32-35,
2012
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Mandana Gruber, Harald Stecher, Martin Tengg and Helmut Schwab Friedel-Crafts Alkylation catalyzed by Methyltransferases
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Stefan Heinl, Daniel Wibberg, Felix G. Eikmeyer, Rafael Szczepanowski, Jochen Blom, Burkhard Linke, Alexander Goesmann, Reingard Grabherr, Helmut Schwab, Alfred Pühler and Andreas Schlüter
Insights into the completely annotated genome of Lactobacillus buchneri CD034, a strain isolated from stable grass silage
Journal of Biotechnology
161,
153-166,
2012
DOI:
https://doi.org/10.1016/j.jbiotec.2012.03.007
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Mandana Gruber, Harald Stecher, Martin Tengg and Helmut Schwab Friedel-Crafts Alkylation catalyzed by Methyltransferases
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Enrique Herrero Acero, Katrin Julia Greimel, Annemarie Marold, Doris Ribitsch, Druzhinina Irina, Georg Gübitz and Christian P Kubicek NEW ENZYMATIC APPROACHES FOR POLYMER MODIFICATION
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Kerstin Steiner, Ivan Hajnal, Romana Wiedner, Andrzej Franciszek Lyskowski, Christian Gruber, Georg Steinkellner, Karl Gruber, Ulf Hanefeld and Helmut Schwab Characterisation of bacterial hydroxynitrile lyases with a cupin fold
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Tamara Wriessnegger, Peter Augustin, Anita Emmerstorfer, Monika Müller, Ivona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler (+)-Nootkatone production in yeasts
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Laura Näätsaari, Beate Mistlberger, Claudia Ruth, Tanja Hajek, Franz Stefan Hartner and Anton Glieder
Deletion of the Pichia pastoris KU70 homologue facilitates platform strain generation for gene expression and synthetic biology
PLoS ONE
7,
e39720,
2012
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https://doi.org/10.1371/journal.pone.0039720
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Andrea Mellitzer, Roland Weis, Anton Glieder and Karlheinz Flicker
Expression of lignocellulolytic enzymes in Pichia pastoris
Microbial Cell Factories
11,
61,
2012
DOI:
https://doi.org/10.1186/1475-2859-11-61
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Andrea Mellitzer, Anton Glieder, Roland Weis, Christoph Reisinger and Karlheinz Flicker
Sensitive high-throughput screening for the detection of reducing sugars
Biotechnology Journal
7,
155-62,
2012
DOI:
https://doi.org/10.1002/biot.201100001
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Mandana Gruber, Harald Stecher, Martin Tengg and Helmut Schwab Friedel-Crafts Alkylation catalyzed by Methyltransferases
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Mandana Gruber, Harald Stecher, Martin Tengg, Peter Remler and Helmut Schwab Alternative Cofactors for AdoMet-dependent Methyltransferases
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Margit Winkler, Anton Glieder and Kerstin Steiner C–X Bond Formation: Hydroxynitrile lyases: From Nature to ApplicationComprehensive Chirality350-371
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Birgit Wilding, Margit Winkler, Regina Kratzer, Margaretha Schiller, Gerlinde Offenmüller, Sigrid Egger, Georg Steinkellner, Andrzej Franciszek Lyskowski, Karl Gruber, Bernd Nidetzky and Norbert Klempier Enzymatic Nitrile Reduction
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Enrique Herrero Acero, Doris Ribitsch, Katrin Julia Greimel, Anita Dellacher, Sabine Zitzenbacher, Annemarie Marold, Rosario Diaz Rodriguez, Gibson Stephen Nyanhongo, Helmut Schwab and Georg Gübitz
Two-step enzymatic functionalisation of polyamide with phenolics
Journal of Molecular Catalysis B
79,
54-60,
2012
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Bettina Halwachs, Gregor Gorkiewicz and Gerhard Thallinger High-throughput characterization and comparison of microbial communitiesComputational Medicine37-57
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Margit Winkler and David O'Hagan Synthesis of Fluorinated Neurotransmitter AnaloguesFluorine in Pharmaceutical and Medicinal Chemistry : From Biophysical Aspects to Clinical Applications299-331
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Bettina Halwachs and Gerhard Thallinger High-Throughput Characterization of Fungal Communities
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Mandana Gruber, Harald Stecher, Martin Tengg and Helmut Schwab Friedel-Crafts Alkylation catalyzed by Methyltransferases
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Kerstin Steiner and Helmut Schwab
Recent advances in rational approaches for enzyme engineerings in rational approaches for enzyme engineering
Computational and Structural Biotechnology Journal
2,
1-12,
2012
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https://doi.org/10.5936/csbj.201209010
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Birgit Wilding, Margit Winkler, Regina Kratzer, Barbara Petschacher, Sigrid Egger, Georg Steinkellner, Andrzej Franciszek Lyskowski, Gerlinde Offenmüller, Margaretha Schiller, Bernd Nidetzky, Karl Gruber and Norbert Klempier Investigations of the substrate scope of nitrile reductase queF
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Zahid Hussain, Romana Wiedner, Kerstin Steiner, Tanja Hajek, Manuela Avi, Bianca Hecher, Angela Sessitsch and Helmut Schwab
Characterization of two bacterial hydroxynitrile lyases with high similarity to cupin superfamily proteins
Applied and Environmental Microbiology
78,
2053-2055,
2012
DOI:
https://doi.org/10.1128/AEM.06899-11
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Anita Emmerstorfer, Monika Müller, Iwona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler S. cerevisiae as Whole-Cell Biocatalyst for Terpenoid Production
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Tamara Wriessnegger, Melanie Hirz, Gerald Richter and Harald Pichler Yeast membrane engineering for improved protein expression
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Tamara Wriessnegger, Peter Andreas Augustin, M. Müller, I. Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler The yeast Pichia pastors as whole cell biocatalyst for the production of terpenoid compounds
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Enrique Herrero Acero, Doris Ribitsch, Annemarie Marold, Katrin Julia Greimel, Georg Steinkellner, Karl Gruber, Helmut Schwab and Georg Gübitz Molecular Approaches to Increase Polyesterase Activity of Cutinase
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Martin Tengg, Harald Stecher, Peter Remler, Inge Eiteljörg, Mandana Gruber and Helmut Schwab
Molecular characterization of the C-Methyltransferase NovO of Streptomyces spheroides, a valuable enzyme for performing Friedel-Crafts alkylation
Journal of Molecular Catalysis B
84,
2-8,
2012
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https://doi.org/10.1016/j.molcatb.2012.03.016
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Kerstin Steiner, Ivan Hajnal, Romana Wiedner, Andrzej Franciszek Lyskowski, Christian Gruber, Georg Steinkellner, Karl Gruber, Ulf Hanefeld and Helmut Schwab Characterisation of bacterial hydroxynitrile lyases
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Doris Ribitsch, Sabine Zitzenbacher, Peter Andreas Augustin, Katharina Schmoelzer, Tibor Czabany, Christiane Luley, Bernd Nidetzky and Helmut Schwab Expression of mammalian glycosyltransferases in yeast
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Katharina Schmoelzer, Deja Kokot, Tibor Czabany, Christiane Luley, Doris Ribitsch, Sabine Zitzenbacher, Peter Andreas Augustin, Andrzej Franciszek Lyskowski, Bernd Nidetzky and Helmut Schwab A novel multifunctional sialyltransferase PdST from Pasteurella dagmatis
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Margit Winkler
Organ Function in Shake Flasks: Recombinant Human Enzymes for the Pharmaceutical Industry
TU Graz Research
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32-35,
2012
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Enrique Herrero Acero, Doris Ribitsch, Rosario Diaz Rodriguez, Katrin Julia Greimel, Annemarie Marold, Helmut Schwab and Georg Gübitz Enzymatic functionalization of synthetic polymers via double enzymatic reaction
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Tanja Knaus, Markus Schober, Bernhard Kepplinger, Martin Faccinelli, Julia Pitzer, Kurt Faber, Peter Macheroux and Ulrike Wagner
Structure and mechanism of an inverting alkylsulfatase from Pseudomonas sp. DSM6611 specific for secondary alkyl sulfates
The FEBS Journal
279,
4374-4384,
2012
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https://doi.org/10.1111/febs.12027
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Florian Krainer, Christian Dietzsch, Tanja Hajek, Christoph Herwig, Oliver Spadiut and Anton Glieder
Recombinant protein expression in Pichia pastoris strains with an engineered methanol utilization pathway
Microbial Cell Factories
11,
22-35,
2012
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https://doi.org/10.1186/1475-2859-11-22
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Regina Kratzer, Katharina Teresa Christina Mädje and Bernd Nidetzky Host cell and expression engineering for development of an E. coli ketoreductase catalyst: Enhancement of formate dehydrogenase activity for regeneration of NADH
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Henrike Brundiek, Stefan Saß, Andrew Evitt, Robert Kourist and Uwe T Bornscheuer
The short form of the recombinant CAL-A-type lipase UM03410 from the smut fungus Ustilago maydis exhibits an inherent trans-fatty acid selectivity
Applied Microbiology and Biotechnology
94,
141-50,
2012
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https://doi.org/10.1007/s00253-012-3903-9
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Kenji Miyamoto, Robert Kourist, Shosuke Yoshida and Hiromichi Ohta Asymmetric decarboxylation of arylmalonates and racemization of profens by arylmalonate decarboxylase and its variants
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Martina Geier 100% double site saturation by individual expression of 400 muteins in Pichia pastoris
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Doris Ribitsch, Enrique Herrero Acero, Katrin Julia Greimel, Inge Eiteljörg, Eva Trotscha, Giuliano Freddi, Helmut Schwab and Georg Gübitz
Characterization of a new cutinase from Thermobifida alba regarding PET-surface hydrolysis
Biocatalysis and Biotransformation
30,
2-9,
2012
DOI:
https://doi.org/10.3109/10242422.2012.644435
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Andreas Braun, Bettina Halwachs, Martina Geier, Katrin Weinhandl, Michael Guggemos, Jan Marienhagen, Anna Joel Ruff, Ulrich Schwaneberg, Daniel E. Torres Pazmiño, Vincent Rabin, Gerhard Thallinger and Anton Glieder
MuteinDB: the mutein database linking substrates, products and enzymatic reactions directly with genetic variants of enzymes
Database - The Journal of Biological Databases and Curation
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bas028-bas028,
2012
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https://doi.org/10.1093/database/bas028
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Andrea Camattari, Katrin Weinhandl, Margit Winkler and Anton Glieder A robust multi-enzymatic assay for in vivo transaminase high-throughput screening
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Henrike B Brundiek, Andrew S. Evitt, Robert Kourist and Uwe T. Bornscheuer
Creation of a lipase highly selective for trans fatty acids by protein engineering
Angewandte Chemie - International Edition
51,
412-414,
2012
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https://doi.org/10.1002/anie.201106126
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Jessica Rehdorf, Geoffrey A Behrens, Giang-Son Nguyen, Robert Kourist and Uwe T Bornscheuer
Pseudomonas putida esterase contains a GGG(A)X-motif confering activity for the kinetic resolution of tertiary alcohols
Applied Microbiology and Biotechnology
93,
1119-26,
2012
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https://doi.org/10.1007/s00253-011-3464-3
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Doris Ribitsch, Sonja Heumann, W. Karl, Jochen Gerlach, R. Leber, Ruth Birner-Grünberger, Karl Gruber, Inge Eiteljörg, Peter Remler, Petra Siegert, J. Lange, Karl-Heinz Maurer, Gabriele Berg, Georg Gübitz and Helmut Schwab
Extracellular serine proteases from Stenotrophomonas maltophilia: screening, isolation and heterologous expression in E.coli.
Journal of Biotechnology
157,
140-147,
2012
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https://doi.org/10.1016/j.jbiotec.2011.09.025
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Doris Ribitsch, Enrique Herrero Acero, Katrin Julia Greimel, Anita Dellacher, Sabine Zitzenbacher, Annemarie Marold, Rosario Diaz Rodriguez, Georg Steinkellner, Karl Gruber, Helmut Schwab and Georg Gübitz
A New Esterase from Thermobifida halotolerans Hydrolyses Polyethylene Terephthalate (PET) and Polylactic Acid (PLA)
e-Polymers
4,
617-629,
2012
DOI:
https://doi.org/10.3390/polym4010617
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Kamila Napora, Natalia Pankiewicz, Manoj N. Sonavane, Stefan Krahulec, Patricia Wildberger, Andrea Camattari, Harald Pichler, Manuela Avi and Margit Winkler Recombinant expression and characterization of a zinc-dependent alcohol dehydrogenase from Yarrowia lipolytica
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Andreas Braun, Martina Geier, Bruno Buehler, Andreas Schmid, Stephan Mauersberger and Anton Glieder
Steroid biotransformations in biphasic systems with Yarrowia lipolytica expressing human liver cytochrome P450 genes
Microbial Cell Factories
11,
106,
2012
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https://doi.org/10.1186/1475-2859-11-106
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Steven P. Hanlon, Andrea Camattari, Sandra Abad, Anton Glieder, Beat Wirz, Matthias Kittelmann, Stephan Lütz and Margit Winkler
Expression of recombinant human flavin monooxygenase and moclobemide-N-oxide synthesis on multi-mg scale
Chemical Communications
48,
6001-6003,
2012
DOI:
https://doi.org/10.1039/c2cc17878h
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Anita Emmerstorfer, M. Müller, I. Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler Saccharomyces cerevisiae as whole-cell biocatalyst for terpenoid production
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Birgit Wilding, Margit Winkler, Regina Kratzer, Barbara Petschacher, Anton Glieder and Norbert Klempier
NITRILE REDUCTASE FROM GEOBACILLUS KAUSTOPHILUS: A POTENTIAL CATALYST FOR A NEW NITRILE BIOTRANSFORMATION REACTION
Advanced Synthesis & Catalysis
354,
2191-2198,
2012
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Ingund Rosales Rodriguez Identification and isolation of GPI anchored proteins from Pichia pastoris and their potential for surface display of recombinant proteins
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Anton Glieder, Andrea Camattari, Thorsten Bachler and Margit Winkler Expression of Recombinant Human Flavin Monooxygenases and application for N-oxidation of Moclobemide
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Kamila Napora, Natalia Pankiewicz, Manoj N. Sonavane, Stefan Krahulec, Patricia Wildberger, Andrea Camattari, Harald Pichler, Manuela Avi and Margit Winkler Recombinant expression and characterization of a zinc-dependent alcohol dehydrogenase from Yarrowia lipolytica.
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Andrzej Lyskowski, Martin Tengg, Georg Steinkellner, Helmut Schwab, Mandana Gruber and Karl Gruber
Crystallisation of the novel S-adenosyl-L-methionine dependent C-methyltransferase CouO from Streptomyces rishiriensis and preliminary diffraction data analysis. Acta Crystallogr., Sect. F: Struct. Biol. Cryst. Commun.
Acta Crystallographica Section F: Structural Biology and Crystallization Communications
68,
698-700,
2012
DOI:
https://doi.org/10.1107/S1744309112017137
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Harald Pichler and Tamara Wriessnegger Pichia pastoris as whole-cell biocatalyst for (+)-nootkatone productionPichia 201248-48
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Katrin Weinhandl, Margit Winkler, Anton Glieder and Andrea Camattari
A novel multi-enzymatic high throughput assay for transaminase activity
Tetrahedron
68,
7586-7590,
2012
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https://doi.org/10.1016/j.tet.2012.06.058
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Birgit Wilding, Cornelia Hojnik, Margit Winkler and Norbert Klempier Synthesis of 7-deazaguanine analogues including a novel biotransformation step
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Martina Geier, Andreas Braun, Anita Emmerstorfer, Harald Pichler and Anton Glieder
Production of human cytochrome P450 2D6 drug metabolites with recombinant microbes--a comparative study
Biotechnology Journal
7,
1346-1358,
2012
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https://doi.org/10.1002/biot.201200187
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Margit Winkler and Andrea Camattari Recombinant Human Flavin Monooxygenases: Expression and Moclobemide N-oxide Synthesis on Semi-Preparative ScaleNew BiotechnologyS236-S237
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Christine Winkler, Harald Pichler and Helmut Schwab Random mutagenesis in Pichia pastoris by resistance cassette transformation
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Enrique Herrero Acero, Elke Scholz, Anita Dellacher, Doris Ribitsch, Georg Steinkellner, Karl Gruber, Helmut Schwab and Georg Gübitz The role of surficial aminoacids on polyester hydrolysis by cutinases
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Katharina Schmoelzer, Deja Kokot, Tibor Czabany, Christiane Luley, Doris Ribitsch, Sabine Zitzenbacher, Peter Andreas Augustin, Bernd Nidetzky and Helmut Schwab Identification, cloning, expression and characterization of a novel multifunctional sialyltransferase from Pasteurella dagmatis
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Kerstin Steiner, Andrzej Franciszek Lyskowski, Ivan Hajnal, Georg Steinkellner, Helmut Schwab and Karl Gruber
Crystallization of a novel metal-containing cupin from Acidobacterium sp. and preliminary diffraction data analysis
Acta Crystallographica Section F: Structural Biology and Crystallization Communications
68,
451-454,
2012
DOI:
https://doi.org/10.1107/S1744309112006550
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Birgit Wilding, Margit Winkler, Regina Kratzer, Gerlinde Offenmüller, Georg Steinkellner, Andrzej Franciszek Lyskowski, Karl Gruber, Bernd Nidetzky and Norbert Klempier Enzymatic Nitrile Reduction
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Margit Winkler and Andrea Camattari Recombinant Human Flavin Monooxygenases: Expression and Moclobemide N-oxide Synthesis on Semi-Preparative Scale
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Enrique Herrero Acero, Doris Ribitsch, Rosario Diaz Rodriguez, Katrin Julia Greimel, Annemarie Marold, Helmut Schwab and Georg Gübitz Enzymatic functionalization of synthetic polymers via two-step enzymatic functionalisation
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Christoph Sygmund, Alexander Gutmann, Iris Krondorfer, Magdalena Kujawa, Anton Glieder, Beate Pscheidt, Dietmar Haltrich, Clemens Peterbauer and Roman Kittl
Simple and efficient expression of Agaricus meleagris pyranose dehydrogenase in Pichia pastoris
Applied Microbiology and Biotechnology
94,
695-704,
2012
DOI:
https://doi.org/DOI:10.1007/s00253-011-3667-7
Alternative link: Link
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Domen Zafred, Andy Nandy, Silvia Wallner, Andrea Camattari, Peter Macheroux and Walter Keller Phl p 4, an exciting allergen
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Ingund Rosales Rodriguez Identification of the alpha mating factor from the improved draft genome sequence of Pichia pastoris CBS7435 and investigating its ability for secretory heterologous protein expression
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Martin Trinker, Andreas Braun, Amin El-Heliebi, Christine Winkler, Orsolya Schwamberger, Georg Steinkellner, Karl Gruber, Ruud Luiten, Wolfgang Skranc, Oliver May, Helmut Schwab and Harald Pichler PLE - reintroducing a valuable biocatalyst into industrial processes
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Georg Steinkellner, Christian Gruber, Tea Pavkov-Keller, Andrzej Franciszek Lyskowski, Orsolya Schwamberger, Kerstin Steiner, Christoph Winkler, Helmut Schwab, Kurt Faber and Karl Gruber Catalophore: Mining of structural databases using 3D-templates
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Doris Ribitsch, Sonja Heumann, Eva Trotscha, Enrique Herrero Acero, Katrin Julia Greimel, Inge Eiteljörg, Peter Remler, Regina Maria Leber, Sigrid Deller, Giuliano Freddi, I. Donelli, K.H. Maurer, P. Siegert, T. Weber, Helmut Schwab and Georg Gübitz
Hydrolysis of polyethyleneterephthalate by para-nitrobenzylesterase from Bacillus subtilis
Biotechnology Progress
27,
951-960,
2011
DOI:
https://doi.org/DOI: 10.1002/btpr.610
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Martin Tengg, Harald Stecher, Peter Remler, Helmut Schwab and Mandana Gruber Methyltransferase NovO - a Versatile Catalyst for Enzymatic Friedel-Crafts Alkylation
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Birgit Wilding, Margit Winkler, Barbara Petschacher, Regina Kratzer, Margaretha Schiller, Sigrid Egger, Bernd Nidetzky, Georg Steinkellner, Andrzej Franciszek Lyskowski, Karl Gruber and Norbert Klempier Nitrile Reduction using Nitrile Reductase
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Andreas Küberl, Jessica Schneider, Gerhard Thallinger, Ingund Anderl, Daniel Wibberg, Tanja Hajek, Sebastian Jaenicke, Karina Brinkrolf, Alexander Goesmann, Rafael Szczepanowski, Alfred Pühler, Helmut Schwab, Anton Glieder and Harald Pichler
High-quality genome sequence of Pichia pastoris CBS7435
Journal of Biotechnology
154,
312-320,
2011
DOI:
https://doi.org/10.1016/j.jbiotec.2011.04.014
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Birgit Wilding, Barbara Petschacher, Margit Winkler, Sigrid Egger, Regina Kratzer, Margaretha Schiller, Bernd Nidetzky, Georg Steinkellner, Andrzej Lyskowski, Karl Gruber and Norbert Klempier Enzymatic Nitrile Reduction
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Sandra Abad, Jozef Nahalka, Margit Winkler, Gabriele Bergler, Robert Speight, Anton Glieder and Bernd Nidetzky
HIGH LEVEL EXPRESSION OF RHODOTORULA GRACILIS D-AMINO ACID OXIDASE IN PICHIA PASTORIS
Biotechnology Letters
33,
557-563,
2011
DOI:
https://doi.org/10.1007/S10529-010-0456-9
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Karim Engelmark Cassimjee, Robert Kourist, Diana Lindberg, Marianne Wittrup Larsen, Nguyen Hong Thanh, Mikael Widersten, Uwe T Bornscheuer and Per Berglund
One-step enzyme extraction and immobilization for biocatalysis applications.
Molecular Biotechnology
6,
463-469,
2011
DOI:
https://doi.org/10.1002/biot.201000357
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Susanne Herter, Giang-Son Nguyen, Mark L Thompson, Fabian Steffen-Munsberg, Frieder Schauer, Uwe T Bornscheuer and Robert Kourist
Comparative analysis of tertiary alcohol esterase activity in bacterial strains isolated from enrichment cultures and from screening strain libraries.
Applied Microbiology and Biotechnology
90,
929-939,
2011
DOI:
https://doi.org/10.1007/s00253-011-3124-7
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R Kourist and U T Bornscheuer
Biocatalytic synthesis of optically active tertiary alcohols
Applied Microbiology and Biotechnology
91,
505-17,
2011
DOI:
https://doi.org/10.1007/s00253-011-3418-9
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Robert Kourist, Pablo Domínguez de María and Kenji Miyamoto
Biocatalytic strategies for the asymmetric synthesis of profens – recent trends and developments
Green Chemistry
,
2607-2618,
2011
DOI:
https://doi.org/10.1039/c1gc15162b
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Birgit Wilding, Norbert Klempier, Barbara Petschacher, Margit Winkler, Sigrid Egger, Regina Kratzer, Bernd Nidetzky, Georg Steinkellner, Andrzej Lyskowski and Karl Gruber Enzymatic Nitrile Reduction using wild type and mutant Nitrile Reductase QueF
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R Kourist and K.‚ Miyamoto
Protein engineering of arylmalonate decarboxylase G74C, an artificial racemase
Biotechnology International
23,
6-9,
2011
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Yusuke Miyauchi, Robert Kourist, Daisuke Uemura and Kenji Miyamoto
Dramatically improved catalytic activity of an artificial (S)-selective arylmalonate decarboxylase by structure-guided directed evolution.
Chemical Communications
47,
7503-7505,
2011
DOI:
https://doi.org/10.1039/c1cc11953b
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Giang-Son Nguyen, Mark L. Thompson, Gideon Grogan, Uwe T. Bornscheuer and Robert Kourist
Identification of novel esterases for the synthesis of sterically demanding chiral alcohols by sequence-structure guided genome mining
Journal of Molecular Catalysis B
70,
88-94,
2011
DOI:
https://doi.org/10.1016/j.molcatb.2011.02.009
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Enrique Herrero Acero, Doris Ribitsch, Georg Steinkellner, Karl Gruber, Katrin Julia Greimel, Inge Eiteljörg, Eva Trotscha, R. Wei, W. Zimmermann, M. Zinn, A. Cavaco-Paulo, G. Freddi, Helmut Schwab and Georg Gübitz
Enzymatic Surface Hydrolysis of PET. Effect of Structural Diversity on Kinetic Properties of Cutinases from Thermobifida
Macromolecules
44,
4632-4640,
2011
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Petra Köfinger, Christian Wels, Shiprad Joshi, Sabine Damm, Elisabeth Steinbauer, Christine Beham-Schmid, Sasa Frank, Helmut Bergler and Helmut Schaider
The cadherin switch in melanoma instigated by HGF is mediated through epithelial-mesenchymal transition regulators.
Pigment cell & melanoma research
24,
382-385,
2011
DOI:
https://doi.org/10.1111/j.1755-148X.2010.00807.x
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Cleiton M Souza, Tatjana M Schwabe, Harald Pichler, Birgit Ploier, Erich Leitner, Xue Li Guan, Markus W Wenk, Isabelle Riezman and Howard Riezman
A stable yeast strain efficiently producing cholesterol instead of ergosterol is functional for tryptophan uptake, but not weak organic acid resistance
Metabolic Engineering
13,
555-569,
2011
DOI:
https://doi.org/10.1016/j.ymben.2011.06.006
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Barbara Petschacher, Monika Müller, Nicole Staunig, Stefaan DeWildeman, Karl Gruber and Anton Glieder Creation of a generally applicable NAD(P)+ regeneration system from a NADH specific NADH oxidase
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Ivan Hajnal, Kerstin Steiner and Helmut Schwab Characterization and engineering of cupin dioxygenases
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Katharina Schmoelzer, Tibor Czabany, Christiane Luley, Doris Ribitsch, Sabine Zitzenbacher, Helmut Schwab and Bernd Nidetzky Production of a hypothetical sialyltransferase from P. dagmatis: Cloning, expression, purification and setup of a screening assay
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Matthias Schittmayer, Anton Glieder, Michael Karl Uhl, Andreas Winkler, Simone Zach, Jörg Schrittwieser, Wolfgang Kroutil, Peter Macheroux, Karl Gruber, Spiros Kambourakis, J. David Rozzell and Margit Winkler
Old Yellow Enzyme catalyzed dehydrogenation of saturated ketones
Advanced Synthesis & Catalysis
252,
268-274,
2011
DOI:
https://doi.org/10.1002/adsc.201000862
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Birgit Wilding, Carina Hasenöhrl, Gary Black, Justin Perry, Margit Winkler and Norbert Klempier PREPARATION OF AN ENANTIOENRICHED TAXOL SIDECHAIN PRECURSOR BY NITRILASE AND NITRILE HYDRATASE
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Andrea Hasmann, Anita Eberl, Konstantin Schneider, K.-U. Schoening, F. Kaufmann, Anton Glieder, J. Kovac, Artur Cavaco-Paulo, Eva Wehrschütz-Sigl and Georg Gübitz
Hydroxylation of polypropylene using the monooxygenase mutant 139-3 from Bacillus megaterium BM3
Biocatalysis and Biotransformation
,
1-6,
2011
DOI:
https://doi.org/10.3109/10242422.2012.645367
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Georg Steinkellner, Christian Gruber, Tea Pavkov-Keller, Andrzej Franciszek Lyskowski, Orsolya Schwamberger, Kerstin Steiner, Christoph Winkler, Helmut Schwab, Kurt Faber and Karl Gruber Identification of two enone-reductases by database mining using 3D active site templates
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Kerstin Steiner, Ivan Hajnal, Andrzej Franciszek Lyskowski, Georg Steinkellner, Karl Gruber and Helmut Schwab Characterisation of bacterial hydroxynitrile lyases with high homology to cupin superfamily proteins
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Tamara Wriessnegger, Peter Augustin, Anita Emmerstorfer, Monika Müller, Iwona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler Pichia pastoris as Whole-Cell Biocatalyst for (+)-Nootkatone Production
Alternative link: Link
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Anita Emmerstorfer, Tamara Wriessnegger, Peter Augustin, Monika Müller, Iwona Kaluzna, Peter Macheroux, Helmut Schwab and Harald Pichler Heterologous Expression of CYP71D55 in S. cerevisiae for (+)-Nootkatone Production
Alternative link: Link
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Harald Stecher, Martin Tengg, Peter Remler, Helmut Schwab, Herfried Griengl and Mandana Gruber Biocatalytic Friedel-Crafts Alkylation
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Julia Feichtinger Development of a Bioinformatic Analytical Approach to Identify Novel Cancer Testis Antigens Involved in Meiosis
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Kerstin Steiner, Ivan Hajnal, Andrzej Franciszek Lyskowski, Georg Steinkellner, Karl Gruber and Helmut Schwab Cupins as scaffolds for novel activities
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Christian Wels, Shiprad Joshi, Petra Köfinger, Helmut Bergler and Helmut Schaider
Transcriptional Activation of ZEB1 by Slug Leads to Cooperative Regulation of the EMT like Phenotype in Melanoma
The Journal of Investigative Dermatology
131,
1877-1885,
2011
DOI:
https://doi.org/10.1038/jid.2011.142
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Andrea Camattari, Margit Winkler, Katrin Weinhandl and Anton Glieder Expression of a branched chain aminotransferase (BCAT) in Pichia pastoris: high throughput screening and process development
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Harald Stecher, Martin Tengg, Peter Remler, Helmut Schwab, Herfried Griengl and Mandana Gruber Biocatalytic Friedel-Crafts Alkylation
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Julia Feichtinger Development of a Bioinformatic Analytical Approach to Identify and Characterise Novel Cancer Testis Antigens.
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Helmut Schwab, Sabine Feichtenhofer and Romana Wiedner Converting enzyme function and enantioselectivity of enzymes
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Kirsten Schroer, Klaus Peter Luef, Franz Stefan Hartner, Anton Glieder and Beate Pscheidt
Engineering the Pichia pastoris methanol oxidation pathway for improved NADH regeneration during whole-cell biotransformation
Metabolic Engineering
12,
8-17,
2010
DOI:
https://doi.org/10.1016/j.ymben.2009.08.006
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Helmut Schwab, Sabine Feichtenhofer and Romana Wiedner Hydroxynitrile lyases: Converting enzyme function and enantioselectivity
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Christine Winkler, Harald Pichler and Helmut Schwab Insights into the Secretory System of the Yeast Pichia pastoris
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Martin Koller, Aid Atlic, Miguel Miranda de Sousa Dias, Angelika Reiterer and Gerhart Braunegg Microbial PHA Production from Waste Raw MaterialsPlastics from Bacteria: Natural Functions and Applications85-119
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Elena Fernández-Álvaro, Robert Kourist, Julia Winter, Dominique Böttcher, Klaus Liebeton, Christian Naumer, Jürgen Eck, Christian Leggewie, Karl-Erich Jaeger, Wolfgang Streit and Uwe T Bornscheuer
Enantioselective kinetic resolution of phenylalkyl carboxylic acids using metagenome-derived esterases.
Microbial Biotechnology
3,
59-64,
2010
DOI:
https://doi.org/10.1111/j.1751-7915.2009.00141.x
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Ulrike Schreiner, Bianca Hecher, Sascha Obrowsky, Kerstin Waich, Norbert Klempier, Georg Steinkellner, Karl Gruber, J. David Rozzell, Anton Glieder and Margit Winkler
Directed evolution of Alcaligenes faecalis nitrilase
Enzyme and Microbial Technology
47,
140-146,
2010
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Doris Ribitsch, W Karl, Ruth Birner-Grünberger, Karl Gruber, Inge Eiteljörg, Peter Remler, Susanne Wieland, Petra Siegert, Karl Maurer and Helmut Schwab
Engineering of choline oxidase from Arthrobacter nicotianae for potential use as biological bleach in detergents.
Applied Microbiology and Biotechnology
87,
1743-1752,
2010
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M Gall, R Kourist, M Schmidt and U T Bornscheuer
The role of the GGGX motif in determining the activity and enantioselectivity of pig liver esterase towards tertiary alcohols
Biocatalysis and Biotransformation
28,
201-208,
2010
DOI:
https://doi.org/10.3109/10242421003753803
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Sandra Abad, Kerstin Kitz, Astrid Hörmann, Ulrike Schreiner, Franz Stefan Hartner and Anton Glieder
Real time PCR based determination of gene copy numbers in Pichia pastoris
Biotechnology Journal
5,
10-10,
2010
DOI:
https://doi.org/10.1002/biot.200900233
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Robert Kourist, Henrike Brundiek and Uwe T. Bornscheuer
Protein engineering and discovery of lipases
European Journal of Lipid Science and Technology
112,
64-74,
2010
DOI:
https://doi.org/10.1002/ejlt.200900143
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R Kourist, H Jochens, S Bartsch, R Kuipers, S K Padhi, M Gall, D Böttcher, H J Joosten and U T Bornscheuer
The alpha/beta-hydrolase fold 3DM database (ABHDB) as a tool for protein engineering
ChemBioChem
11,
1635-1643,
2010
DOI:
https://doi.org/10.1002/cbic.201000213
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Giang-Son Nguyen, Robert Kourist, Monica Paravidino, Anke Hummel, Jessica Rehdorf, Romano V. a. Orru, Ulf Hanefeld and Uwe T. Bornscheuer
An Enzymatic Toolbox for the Kinetic Resolution of 2-(Pyridin- x -yl)but-3-yn-2-ols and Tertiary Cyanohydrins
European Journal of Organic Chemistry
,
2753-2758,
2010
DOI:
https://doi.org/10.1002/ejoc.201000193
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Matthias Theurer, Peter Fischer, Angelika Baro, Giang Son Nguyen, Robert Kourist, Uwe Bornscheuer and Sabine Laschat
Formation of chiral tertiary homoallylic alcohols via Evans aldol reaction or enzymatic resolution and their influence on the Sharpless asymmetric dihydroxylation
Tetrahedron
66,
3814-3823,
2010
DOI:
https://doi.org/10.1016/j.tet.2010.03.048
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Martin Tengg, Harald Stecher, Peter Remler, Helmut Schwab, Herfried Griengl and Mandana Gruber Characterization of two Methyltransferases for Novel Biocatalytic C-C Bond Formation
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Barbara Petschacher, Nicole Staunig, Karl Gruber, Anton Glieder, Stefaan DeWildeman, Natascha Sereinig, Monika Müller and Oliver May Changing the cofactor specificity of an NADH oxidase for efficient NADP+ recycling
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Laura Näätsaari, Florian Krainer, Michael Schubert, Gerhard Thallinger and Anton Glieder Identification of horseradish peroxidase isoenzymes and their heterologous expression in Pichia pastoris
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Martin Tengg, Harald Stecher, Peter Remler, Helmut Schwab, Herfried Griengl and Mandana Gruber Characterization of two Methyltransferases for Novel Biocatalytic C-C Bond Formation
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Sandra Abad, Jozef Nahalka, Gabriele Bergler, S. Alison Arnold, Robert Speight, I. Fotheringhan, Bernd Nidetzky and Anton Glieder
Stepwise engineering of a Pichia pastoris D-amino acid whole cell catalyst
Microbial Cell Factories
9,
24-24,
2010
DOI:
https://doi.org/10.1186/1475-2859-9-24
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Laura Näätsaari, Florian Krainer and Anton Glieder PRODUCTION, CHARACTERIZATION AND ENGINEERING OF HORSERADISH PEROXIDASE ISOENZYMES
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Sabine Damm, Petra Köfinger, Martina Stefan, Christian Wels, Gabor Mehes, Eva Richtig, Helmut Kerl, Marcus Otte and Helmut Schaider
HGF-promoted motility in primary human melanocytes depends on CD44v6 regulated via NF-kappa B, Egr-1, and C/EBP-beta
The Journal of Investigative Dermatology
,
1893-1903,
2010
DOI:
https://doi.org/10.1038/jid.2010.45
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Margit Winkler, Ulrike Schreiner, Robert Speight, Sandra Abad, Thorsten Bachler, Ian Archer, Ian Fotheringham and Anton Glieder Development of a tailored D-Amino Acid Oxidase Expressing Whole Cell Biocatalyst
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Ulrike Schreiner, Georg Steinkellner, Anton Glieder, J. David Rozzell and Margit Winkler
IMPROVED FITNESS OF ARABIDOPSIS THALIANA NITRILASE 2
ChemCatChem
2,
263-267,
2010
DOI:
https://doi.org/10.1002/cctc.200900212
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Doris Ribitsch, W Karl, Ruth Birner-Grünberger, Karl Gruber, Inge Eiteljörg, Peter Remler, Susanne Wieland, Petra Siegert, Karl Maurer and Helmut Schwab
C-terminal truncation of a metagenome-derived detergent protease for effective expression in E. coli.
Journal of Biotechnology
150,
408-416,
2010
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Claudia Ruth and Anton Glieder
Perspectives on synthetic promoters for biocatalysis and biotransformation
ChemBioChem
11,
761-765,
2010
DOI:
https://doi.org/10.1002/cbic.200900761
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Zahid Hussain, Romana Wiedner, Kerstin Steiner, Tanja Hajek, Manuela Avi, Bianca Hecher, Birgit Krenn, Angela Sessitsch and Helmut Schwab Characterisation of two bacterial hydroxynitrile lyases with high homology to cupin superfamily proteins
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Ulrike Schreiner, Norbert Klempier, J. David Rozzell, Anton Glieder and Margit Winkler Engineered Alcaligenes faecalis nitrilases
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Daniel E Torres Pazmiño, Margit Winkler, Anton Glieder and Marco W Fraaije
Monooxygenases as biocatalysts: classification, mechanistic aspects and biotechnological applications
Journal of Biotechnology
146,
9-24,
2010
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Martina Geier Expression and Characterization of Cytochrome P450 2D6 Variants in Pichia pastoris
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Helmut Schwab, Romana Wiedner and Sabine Feichtenhofer Hydroxynitrile lyases: Converting enzyme function and enantioselectivity
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Harald Stecher, Martin Tengg, Peter Remler, Helmut Schwab, Herfried Griengl and Mandana Gruber Biocatalytic Friedel-Crafts Alkylation
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Katharina Teresa Christina Mädje Optimisation of internal cofactor regeneration by host and expression engineering for the whole-cell bioreduction of carbonyl substrates
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Harald Pichler, Martin Kietzmann, Andreas Braun, Amin El-Heliebi, Christine Winkler, Orsolya Szabo, Georg Steinkellner, Karl Gruber, Ruud Luiten, Wolfgang Skranc, Oliver May and Helmut Schwab Pig Liver Esterase - Re-introducing a Valuable Biocatalyst into Industrial Processes
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Norbert Klempier, Birgit Wilding and Margit Winkler Biotransformation of Purine and Pyrimidine Carbonitriles
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